Results 1 to 10 of about 2,411,299 (185)
Delivery of biologics: Topical administration
Biomaterials, 2023 Biologics are unaffordable to a large majority of the global population because of prohibitively expensive fermentation systems, purification and the requirement for cold chain for storage and transportation. Limitations of current production and delivery systems of biologics were evident during the recent pandemic when 90% are delivered using invasive
Rachel J. Kulchar +5 more
openaire +5 more sources
Pharmaceuticals, 2022 Xerostomia is linked to an increased risk of dental caries, oral fungal infections, and speaking/swallowing difficulties, factors that may significantly degrade patients’ life, socially- or emotionally-wise.
Afroditi Kapourani +2 more
doaj +2 more sources
Systemic and topical administration of spermidine accelerates skin wound healing
Cell Communication and Signaling, 2021 Background The skin wound healing process is regulated by various cytokines, chemokines, and growth factors. Recent reports have demonstrated that spermine/spermidine (SPD) promote wound healing through urokinase-type plasminogen activator (uPA)/uPA ...
Daisuke Ito +5 more
doaj +2 more sources
Transdermal and Topical Drug Administration in the Treatment of Pain [PDF]
Molecules, 2018 The comprehensive treatment of pain is multidimodal, with pharmacotherapy playing a key role. An effective therapy for pain depends on the intensity and type of pain, the patients’ age, comorbidities, and appropriate choice of analgesic, its dose and route of administration.
Wojciech Leppert +3 more
openaire +6 more sources
Scientifica, 2022 This research aimed to determine the topical administration effect of the combination of Sargassum duplicatum and Garcinia mangostana extracts to ameliorate diabetic open wound healing.
Dwi Winarni +10 more
doaj +2 more sources
BJS Open, 2019 Background Topical administration of tranexamic acid (TXA) reduces bleeding from surgical wounds similarly to intravenous use, but with negligible risk of adverse systemic events. Topical use is expanding, but is off‐label.
T. A. Eikebrokk +5 more
doaj +2 more sources
Corneal Infection Therapy with Topical Bacteriophage Administration [PDF]
The Open Ophthalmology Journal, 2015 Staphylococcus aureus is a major pathogen in bacterial keratitis, a vision-threatening disease. Although the incidence of S. aureus keratitis varies worldwide, the increasing trend of resistance to certain antibiotics makes this condition an important, global, healthcare concern.
Jean-Marc Legeais +2 more
openaire +4 more sources
Acute Hyperglycemia Due to Topical Corticosteroid Administration
Case Reports in Endocrinology, 2019 We present the case of a 71-year-old man with longstanding, previously well-controlled type 1 diabetes who developed acute hyperglycemia. His insulin requirements, via his insulin pump, increased to nearly five times his typical daily dose.
Laura Y. Sue, Anna Milanesi
doaj +6 more sources
Design of solid lipid nanoparticles for caffeine topical administration [PDF]
Drug Delivery, 2014 Solid lipid nanoparticles (SLN) are drug carriers possessing numerous features useful for topical application. A copious scientific literature outlined their ability as potential delivery systems for lipophilic drugs, while the entrapment of a hydrophilic drug inside the hydrophobic matrix of SLN is often difficult to obtain.To develop SLN intended for
PUGLIA, CARMELO +6 more
openaire +6 more sources
Topical timolol for superficial cutaneous infantile hemangiomas in very preterm infants [PDF]
Vojnosanitetski Pregled, 2021 Introduction. Infantile hemangiomas (IHs) occur 3 to 4 times more frequently in preterm infants than in those born at term. Yet, data about efficacy and safety of topical therapy for IHs in preterm infants, especially in those born with very low ...
Matić Aleksandra +2 more
doaj +1 more source