Microneedles enhance the efficacy of topical dental anesthesia in male subjects: a randomized controlled trial [PDF]
Brazilian Oral Research: This study aimed to determine whether microneedles (MN) can enhance the efficacy of a commercially available topical anesthetic (EMLA®) when applied to the palatal mucosa.
Stephany Di Carla Santos +5 more
doaj +3 more sources
Cardiovascular Safety Signals of Oral Versus Topical Minoxidil in FAERS: A Disproportionality Analysis (Analytic Cohort 2012–2025) [PDF]
LifeOral minoxidil, including low-dose regimens, is increasingly used off-label for alopecia, but cardiovascular safety remains a clinical concern. We compared cardiovascular adverse event reporting patterns for oral versus topical minoxidil using a ...
Hima Bindu Makkena, Vikas Kasu
doaj +2 more sources
Acute Hyperglycemia Due to Topical Corticosteroid Administration
Case Reports in Endocrinology, 2019 We present the case of a 71-year-old man with longstanding, previously well-controlled type 1 diabetes who developed acute hyperglycemia. His insulin requirements, via his insulin pump, increased to nearly five times his typical daily dose.
Laura Y. Sue, Anna Milanesi
doaj +5 more sources
Topical timolol for superficial cutaneous infantile hemangiomas in very preterm infants [PDF]
Vojnosanitetski Pregled, 2021 Introduction. Infantile hemangiomas (IHs) occur 3 to 4 times more frequently in preterm infants than in those born at term. Yet, data about efficacy and safety of topical therapy for IHs in preterm infants, especially in those born with very low ...
Matić Aleksandra +2 more
doaj +1 more source
A promising alternative for mature skin: the effects of phytoestrogens on human skin and its topical use [PDF]
Revista Brasileira de Cirurgia Plástica, 2023 Skin quality deteriorates with age for various reasons, including hormone deficiencies. In women, the decline in estrogen levels during menopause plays an important role in skin degeneration, with consequent atrophy, collagen reduction, loss of ...
Júnia Lira Carneiro +3 more
doaj +1 more source
Delivery of biologics: Topical administration
Biomaterials, 2023 Biologics are unaffordable to a large majority of the global population because of prohibitively expensive fermentation systems, purification and the requirement for cold chain for storage and transportation. Limitations of current production and delivery systems of biologics were evident during the recent pandemic when 90% are delivered using invasive
Rachel J. Kulchar +5 more
openaire +4 more sources
Topical (S)-ketamine for pain management of postherpetic neuralgia [PDF]
Anais Brasileiros de Dermatologia, 2012 Herpes zoster infection may cause postherpetic neuralgia, which is defined by prolonged pain predominantly mediated by central nervous system hypersensitivity.
Guilherme Antonio Moreira de Barros +4 more
doaj +1 more source
Pharmaceuticals, 2022 Xerostomia is linked to an increased risk of dental caries, oral fungal infections, and speaking/swallowing difficulties, factors that may significantly degrade patients’ life, socially- or emotionally-wise.
Afroditi Kapourani +2 more
doaj +1 more source
Cryoanesthesia with ethyl chloride spray versus 5% lidocaine gel in alleviating oral local anesthetic injection pain for buccal anaesthesia: A randomized clinical (controlled) trial [PDF]
Journal of Dental Research, Dental Clinics, Dental Prospects, 2023 Background. Numbing the area of oral mucosa with cold application prior to administration of regional anesthesia has been widely used by various dentists in alleviating pain caused by needle prick.
Hira Abbasi +5 more
doaj +1 more source
Effects of Rusanda Spa balneotherapy combined with calcipotriol on plaque psoriasis [PDF]
Vojnosanitetski Pregled, 2015 Background/Aim. Treatment of psoriasis is very complex and there are no still universal, nor unique treatment modalities. Apart from conventional treatment, which includes topical calcipotriol (vitamin D3 analogue), balneotherapy is drawing ...
Golušin Zoran +5 more
doaj +1 more source