Results 11 to 20 of about 2,390,183 (202)

Transdermal and Topical Drug Administration in the Treatment of Pain [PDF]

open access: yesMolecules, 2018
The comprehensive treatment of pain is multidimodal, with pharmacotherapy playing a key role. An effective therapy for pain depends on the intensity and type of pain, the patients’ age, comorbidities, and appropriate choice of analgesic, its dose and ...
W. Leppert   +3 more
semanticscholar   +5 more sources

Delivery of biologics: Topical administration.

open access: yesBiomaterials, 2023
Biologics are unaffordable to a large majority of the global population because of prohibitively expensive fermentation systems, purification and the requirement for cold chain for storage and transportation. Limitations of current production and delivery systems of biologics were evident during the recent pandemic when 90% are delivered using invasive
R. Kulchar   +5 more
semanticscholar   +5 more sources

Acute Hyperglycemia Due to Topical Corticosteroid Administration

open access: yesCase Reports in Endocrinology, 2019
We present the case of a 71-year-old man with longstanding, previously well-controlled type 1 diabetes who developed acute hyperglycemia. His insulin requirements, via his insulin pump, increased to nearly five times his typical daily dose.
Laura Y. Sue, Anna Milanesi
doaj   +5 more sources

Corneal Infection Therapy with Topical Bacteriophage Administration [PDF]

open access: yesThe Open Ophthalmology Journal, 2015
Staphylococcus aureus is a major pathogen in bacterial keratitis, a vision-threatening disease. Although the incidence of S. aureus keratitis varies worldwide, the increasing trend of resistance to certain antibiotics makes this condition an important ...
A. Fadlallah, E. Chelala, J. Legeais
semanticscholar   +4 more sources

mTHPC pharmacokinetics following topical administration [PDF]

open access: yesSPIE Proceedings, 2006
Measurements of concentration of sensitizers for photodynamic therapy can provide important information in the dosimetry planning and can also give input to the optimal time for treatment. There has been skepticism towards fluorescence techniques for this purpose, as the signal depends on the fluorescence yield and optical properties of the tissue ...
Johansson, Ann   +10 more
openaire   +3 more sources

Topical Administration of Cannabidiol: Influence of Vehicle-Related Aspects on Skin Permeation Process

open access: yesPharmaceuticals, 2020
Cannabidiol (CBD) is a non-psychoactive cannabinoid isolated from Cannabis sativa which, given its claimed beneficial properties and therapeutic potential, has lately aroused considerable attention from the scientific community.
A. Casiraghi   +4 more
semanticscholar   +1 more source

Combined topical and systemic administration with human adipose-derived mesenchymal stem cells (hADSC) and hADSC-derived exosomes markedly promoted cutaneous wound healing and regeneration

open access: yesStem cell research & therapeutics, 2020
Cutaneous wound healing and regeneration have become a recognized health challenge in the world, which causes severe damage to the mental and physical health of patients.
Yang Zhou   +11 more
semanticscholar   +1 more source

Effect of topical ketanserin administration on intraocular pressure. [PDF]

open access: yesBritish Journal of Ophthalmology, 1993
The effect of topical ketanserin on intraocular pressure (IOP) in normotensive and hypertensive eyes was evaluated. The study was performed on 10 healthy volunteers and 10 glaucomatous patients. Systolic arterial blood pressure (SBP), diastolic arterial blood pressure (DBP), heart rate (HR), IOP, tonographic outflow facility, pupil diameter, corneal ...
COSTAGLIOLA, Ciro   +5 more
openaire   +7 more sources

Lipid vesicular gels for topical administration of antioxidants

open access: yesColloids and Surfaces B: Biointerfaces, 2022
The application of a formulation on the skin represents an effective way to deliver bio-active molecules for therapeutical purposes. Moreover, the outermost skin layer, the stratum corneum, can be overcome by employing chemical permeation enhancers and edge activators as components.
Fornasier, Marco   +5 more
openaire   +4 more sources

A Novel First-Line Treatment Alternative for Noncomplicated Idiopathic Granulomatous Mastitis: Combined İntralesional Steroid İnjection with Topical Steroid Administration

open access: yesBreast Care, 2020
Background: Idiopathic granulomatous mastitis (IGM) is a rare form of nonlactational mastitis. Due to the small number of case series and consequently inadequate prospective studies, there is still no consensus on the optimal treatment of IGM.
O. Toktaş   +11 more
semanticscholar   +1 more source

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