Results 31 to 40 of about 192,780 (192)

The combined use of oral and topical tranexamic acid is a safe, efficient and low-cost method in reducing blood loss and transfusion rates in total knee arthroplasty

Journal of Orthopaedic Surgery, 2017
Aims: The combined (IV (intravenous) + topical) use of tranexamic acid (TXA) has been shown to be a safe method and more effective than single (IV or topical) application.
Deniz Cankaya, Uygar Dasar, Ahmet Burak Satilmis, Serdar Hakan Basaran, Mustafa Akkaya, Murat Bozkurt   +5 more
doaj   +1 more source

Wet wrap dressings as a rescue therapy option for erythrodermic psoriasis [PDF]

Anais Brasileiros de Dermatologia, 2018
: Wet wrap dressings provide an ancillary treatment option for erythrodermic patients. Wet wrap therapy consists of the application of topical corticosteroids on all affected surfaces, followed by the application of a warm moist cotton cloth with a dry ...
Beatriz Regina de Fatima Navrotski, Francielle Melina Nihi, Michael Joseph Camilleri, Felipe Bochnia Cerci   +3 more
doaj   +1 more source

Effect of recombinant human nerve growth factor eye drops in patients with dry eye: a phase IIa, open label, multiple-dose study [PDF]

, 2019
Background: Dry eye disease (DED) affects more than 14% of the elderly population causing decrease of quality of life, high costs and vision impairment.
Allegretti, M., Ferrari, M., Garhoefer, G., Lambiase, A., Mantelli, F., Sacchetti, M., Schmetterer, L., Schmidl, D.   +7 more
core   +1 more source

Transdermal evaluation of caffeine in different formulations and excipients [PDF]

, 2013
Background: The stratum corneum(SC) forms adifficultphysical barrier fordrugs to pass through the skin. Several strategieswere developed to overcome this barrier.Optimization of topical drug formulations by selected excipients may facilitate the ...
Boonen, Jente, Burvenich, Christian, De Spiegeleer, Bart, Mehuys, Els, Peremans, Kathelijne, Remon, Jean Paul, Roche, Nathalie, Veryser, Lieselotte   +7 more
core   +2 more sources

Improved Biosafety and Transdermal Delivery of Aconitine via Diethylene Glycol Monoethyl Ether-Mediated Microemulsion Assisted with Microneedles

Pharmaceutics, 2020
In the current study, diethylene glycol monoethyl ether-mediated microemulsions were combined with microneedles for enhanced transdermal aconitine delivery.
Yongtai Zhang, Hongmei Hu, Qian Jing, Zhi Wang, Zehui He, Tong Wu, Nian-Ping Feng   +6 more
doaj   +1 more source

Central Serous Chorioretinopathy in a 14-year-old atopic boy: a case report

Italian Journal of Pediatrics, 2023
Background Corticosteroids are widely used in medicine. Few cases of central serous chorioretinopathy (CSC) have been reported following topical corticosteroid administration.
Stefano Ranno, Liviana Fontanel, Edoardo Ruggiero, Paolo Nucci, Paolo Radice, Simone Donati   +5 more
doaj   +1 more source

Fungicidal activity plus reservoir effect allow short treatment courses with terbinafine in tinea pedis [PDF]

, 2008
Terbinafine, a synthetic allylamine, exerts fungicidal activity against dermatophytes, the causative pathogens of tinea pedis. As proven in numerous clinical trials, tinea pedis can be effectively and safely treated by topical terbinafine.
Korting, Hans Christian, Schäfer-Korting, Monika, Schöllmann, C.   +2 more
core   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Cytotoxicity and effect on wound re‐epithelialization after topical administration of tranexamic acid

BJS Open, 2019
Background Topical administration of tranexamic acid (TXA) reduces bleeding from surgical wounds similarly to intravenous use, but with negligible risk of adverse systemic events. Topical use is expanding, but is off‐label.
T. A. Eikebrokk, B. S. Vassmyr, K. Ausen, C. Gravastrand, O. Spigset, B. Pukstad   +5 more
doaj   +1 more source

Pharmacogenetics of ophthalmic topical β-blockers [PDF]

, 2008
Glaucoma is the second leading cause of blindness worldwide. The primary glaucoma risk factor is elevated intraocular pressure. Topical β-blockers are affordable and widely used to lower intraocular pressure.
McCarty, Catherine A., Patchett, Richard, Sidjanin, Duska J., Smith, Edward M., Wilke, Russell A.   +4 more
core   +1 more source