Results 1 to 10 of about 1,382,625 (239)

Neoantigen‐reactive T cell: An emerging role in adoptive cellular immunotherapy [PDF]

MedComm, 2021
Adoptive cellular immunotherapy harnessing the intrinsic immune system for precise treatment has exhibited preliminary success against malignant tumors.
Yicheng Zhu, Youkun Qian, Zhile Li, Yangyang Li, Bin Li   +4 more
doaj   +3 more sources

Adoptive cellular immunotherapy for solid neoplasms beyond CAR-T [PDF]

Molecular Cancer, 2023
In recent decades, immune checkpoint blockade and chimeric antigen receptor T cell (CAR-T) therapy are two milestone achievements in clinical immunotherapy. However, both show limited efficacies in most solid neoplasms, which necessitates the exploration
Qiaofei Liu, Jiayi Li, Huaijin Zheng, Sen Yang, Yuze Hua, Nan Huang, Jorg Kleeff, Quan Liao, Wenming Wu   +8 more
doaj   +3 more sources

Current Situation and Prospect of Adoptive Cellular Immunotherapy for Malignancies [PDF]

Technology in Cancer Research & Treatment, 2023
Adoptive cell immunotherapy (ACT) is an innovative promising treatment for tumors. ACT is characterized by the infusion of active anti-tumor immune cells (specific and non-specific) into patients to kill tumor cells either directly or indirectly by ...
Dong Zhao PhD, Dantong Zhu PhD, Fei Cai MM, Mingzhe Jiang PhD, Xuefei Liu PhD, Tingting Li MM, Zhendong Zheng PhD   +6 more
doaj   +2 more sources

Advances in adoptive cellular immunotherapy and therapeutic breakthroughs in multiple myeloma [PDF]

Experimental Hematology & Oncology
The basic idea of modulating the immune system to better recognize and fight tumor cells has led to the successful introduction of adoptive cellular immunotherapy (ACT).
Jingjing Pu, Ting Liu, Amit Sharma, Liping Jiang, Feng Wei, Xiubao Ren, Ingo G. H. Schmidt-Wolf, Jian Hou   +7 more
doaj   +2 more sources

Blood microbiota diversity determines response of advanced colorectal cancer to chemotherapy combined with adoptive T cell immunotherapy

OncoImmunology, 2021
Human microbiota influence the response of malignancies to treatment with immune checkpoint blockade; however, their impact on other forms of immunotherapy is poorly understood.
Duo Yang, Xiaoli Wang, Xinna Zhou, Jing Zhao, Huabing Yang, Shuo Wang, Michael A. Morse, Jiangping Wu, Yanhua Yuan, Sha Li, Amy Hobeika, Herbert Kim Lyerly, Jun Ren   +12 more
doaj   +2 more sources

Advancements in adoptive CAR immune cell immunotherapy synergistically combined with multimodal approaches for tumor treatment

Bioactive Materials
Adoptive immunotherapy, notably involving chimeric antigen receptor (CAR)-T cells, has obtained Food and Drug Administration (FDA) approval as a treatment for various hematological malignancies, demonstrating promising preclinical efficacy against ...
Yun Chang, Mingyang Chang, Xiaoping Bao, Cheng Dong   +3 more
doaj   +3 more sources

Thapsigargin-Stimulated LAD2 Human Mast Cell Line Is a Potent Cellular Adjuvant for the Maturation of Monocyte-Derived Dendritic Cells for Adoptive Cellular Immunotherapy [PDF]

International Journal of Molecular Sciences, 2021
Pavla Taborska, Dmitry Stakheev, Jiřina Bartůňková   +2 more
exaly   +2 more sources

Adoptive cellular immunotherapy combined with chemotherapy versus chemotherapy alone in Chinese patients with metastatic colorectal cancer: a cost-effectiveness analysis to inform drug pricing [PDF]

Frontiers in Oncology
Huo Liman, Yangyang Duan
exaly   +2 more sources

Associação Brasileira de Hematologia, Hematologia, Hemoterapia e Terapia Celular Consensus on genetically modified cells. Review article: Cell therapy in solid tumors

Hematology, Transfusion and Cell Therapy, 2021
The use of immunotherapy in cancer treatment over the past decade has resulted in significant advances and improvements in cancer patients survival with the use of checkpoint inhibitors.
Mirella Nardo, Tatiane C. Motta, Leandro M. Colli, Mauro P. Avanzi   +3 more
doaj   +1 more source

The Current Application and Future Prospects of Astragalus Polysaccharide Combined With Cancer Immunotherapy: A Review

Frontiers in Pharmacology, 2021
So far, immunotherapy has been shown to have impressive effects on different cancers in clinical trials. All those immunotherapies are generally derived from three main therapeutic approaches: immune checkpoint inhibitors, immune cell vaccination, and ...
Fanming Kong, Fanming Kong, Tianqi Chen, Tianqi Chen, Xiaojiang Li, Xiaojiang Li, Yingjie Jia, Yingjie Jia   +7 more
doaj   +1 more source