Results 11 to 20 of about 1,382,625 (239)

In vivo application of recombinant interleukin 2 in the immunotherapy of established cytomegalovirus infection [PDF]

, 1987
We have shown in a murine model system for cytomegalovirus (CMV) disease in the immunocompromised host that in vivo application of recombinant human IL-2 (rhIL-2) can enhance the antiviral effect of a limited number of CD8+T lymphocytes, not only in ...
Reddehase, Matthias J., W Mutter, Koszinowski, Ulrich H., Wolfgang Mutter, J. Reddehase, M J Reddehase, U H Koszinowski, Koszinowski, Ulrich, Mutter, Wolfgang, Ulrich H. Koszinowski   +9 more
core   +2 more sources

Advances in Human Dendritic Cell-Based Immunotherapy Against Gastrointestinal Cancer

Frontiers in Immunology, 2022
Dendritic cells (DCs), the strongest antigen-presenting cells, are a focus for orchestrating the immune system in the fight against cancer. Basic scientific investigations elucidating the cellular biology of the DCs have resulted in new strategies in ...
Ling Ni
doaj   +1 more source

Antibodies Are Not Essential for the Resolution of Primary Cytomegalovirus Infection but Limit Dissemination of Recurrent Virus [PDF]

, 1994
Virus shedding from the epithelial cells of the serous acini of salivary glands is a major source for the horizontal transmission of cytomegalovirus. These cells are, different to other tissues, exempt from CD8 T lymphocyte control. CD4 T lymphocytes are
Crnkovic, Irena, Pavic, Ivica, Koszinowski, Ulrich H., Lucin, Pero, Polic, Bojan, Jonjic, Stipan   +5 more
core   +2 more sources

Immunotherapy for the treatment of multiple myeloma

Frontiers in Immunology, 2022
Despite advances in treatment for multiple myeloma, the majority of patients ultimately develop relapsed disease marked by immune evasion and resistance to standard therapy.
Leora S. Boussi, Zachary M. Avigan, Jacalyn Rosenblatt   +2 more
doaj   +1 more source

The Cellular and Molecular Immunotherapy in Prostate Cancer

Vaccines, 2022
In recent history, immunotherapy has become a viable cancer therapeutic option. However, over many years, its tenets have changed, and it now comprises a range of cancer-focused immunotherapies. Clinical trials are currently looking into monotherapies or
Anirban Goutam Mukherjee, Uddesh Ramesh Wanjari, D. S. Prabakaran, Raja Ganesan, Kaviyarasi Renu, Abhijit Dey, Balachandar Vellingiri, Sabariswaran Kandasamy, Thiyagarajan Ramesh, Abilash Valsala Gopalakrishnan   +9 more
doaj   +1 more source

Promises and Pitfalls of Next-Generation Treg Adoptive Immunotherapy

, 2023
Regulatory T cells (Tregs) are fundamental to maintaining immune homeostasis by inhibiting immune responses to self-antigens and preventing the excessive activation of the immune system.
Ioanna Sakellari, Panayiota Christofi, Nikoleta Psatha, Evangelia Yannaki, Anastasia Papadopoulou, Chrysoula Pantazi   +5 more
core   +1 more source

Immunotherapy of lung cancer: An update [PDF]

, 2006
In Germany lung cancer is the leading cause of cancer-associated death in men. Surgery, chemotherapy and radiation may enhance survival of patients suffering from lung cancer but the enhancement is typically transient and mostly absent with advanced ...
Hatz, R. A., Jauch, Karl-Walter, van den Engel, N.K., Fox, B.A., Grützner, S., Hatz, R.A., Rüttinger, D., Fox, B. A., Jauch, K.-W., Winter, H., van den Engel, N. K., Schendel, D. J., Pohlac, H., Pohla, H., Schlemmer, M., Schendel, D.J.   +15 more
core   +1 more source

Adoptive Immunotherapy in Chimeras with Donor Lymphocytes [PDF]

, 2003
Allogeneic stem cell transplantation has a well-defined indication in the treatment of hematological malignancies. The beneficial immune effect of allogeneic marrow transplantation has long been known, but only recently have methods been developed to ...
Kolb, Hans-Jochem, Roskrow, Marie, Guenther, Wolfgang, Schmid, Christoph, Ledderose, Georg, Weber, Martin, Chen, Xiao, Schleuning, Michael, Woiciechowski, Anja   +8 more
core   +1 more source

T-Cell Dysfunction as a Limitation of Adoptive Immunotherapy: Current Concepts and Mitigation Strategies

, 2021
Over the last decades, cellular immunotherapy has revealed its curative potential. However, inherent physiological characteristics of immune cells can limit the potency of this approach.
Jean-Sébastien Delisle, Valérie Janelle   +1 more
core   +1 more source

Natural killer cell-derived exosomes for cancer immunotherapy: innovative therapeutics art

Cancer Cell International, 2023
Chimeric antigen receptor natural killer cells (CAR-NK) promote off-the-shelf cellular therapy for solid tumors and malignancy.However,, the development of CAR-NK is due to their immune surveillance uncertainty and cytotoxicity challenge was restricted ...
Zahra Hatami, Zahra Sadat Hashemi, Mohamad Eftekhary, Ala Amiri, Vahid Karpisheh, Kaveh Nasrollahi, Reza Jafari   +6 more
doaj   +1 more source