Results 51 to 60 of about 306,104 (338)
Novel Immunotherapeutic Approach in Gastric Cancer
Acta Medica Bulgarica, 2020 Gastric cancer (GC) is suitable for immunotherapy because 80% of it display microsatellite and chromosomal instability, some mutations and DNA hypermethylation. Therefore, GC is more immunogenic.
Gulubova M. +6 more
doaj +1 more source
Human Vaccines & Immunotherapeutics, 2022 A 74-yr-old man underwent thoracic laparoscopy combined with radical gastrectomy, and the postoperative pathological diagnosis was esophageal and gastric cardia cancer pT3N1M0, pStage IIB. Immunohistochemical staining for HER2 (3+) and PD-L1 (
Wei-Ling Li +5 more
doaj +1 more source
Generation and application of human induced‐stem cell memory T cells for adoptive immunotherapy
Cancer Science, 2018 Adoptive T‐cell therapy is an effective strategy for cancer immunotherapy. However, infused T cells frequently become functionally exhausted, and consequently offer a poor prognosis after transplantation into patients.
T. Kondo +10 more
semanticscholar +1 more source
NMDAR‐Antibody Encephalitis Diagnosed With Primary Central Nervous System Lymphoma: A Case Series
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT N‐methyl‐D‐aspartate receptor‐antibody encephalitis (NMDAR encephalitis) is one of the most common forms of autoimmune encephalitis, with a paraneoplastic relationship described in approximately 38%. Primary central nervous system lymphoma (PCNSL) is a rare hematologic malignancy that is not often considered as the underlying neoplasm in this ...
Soo Hyun Ahn +4 more
wiley +1 more source
Nature Communications, 2018 Adoptive T-cell therapy is a promising therapeutic approach for cancer patients. The use of allogeneic T-cell grafts will improve its applicability and versatility provided that inherent allogeneic responses are controlled.
Yuki Kagoya +8 more
semanticscholar +1 more source
Advanced Biology, EarlyView.Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi +4 more
wiley +1 more source
Journal of Medical Science, 2014 Donor lymphocyte infusion is used to increase the graft versus tumor (GVT) effect after allogeneic hematopoietic cell transplant. The limited spectrum of activity and high risk of graft versus host disease (GVHD) remain major limitations of this approach.
Eliza P. Kwiatkowska-Borowczyk +7 more
doaj +1 more source
Cancer immunotherapies: advances and bottlenecks
Frontiers in Immunology, 2023 Immunotherapy has ushered in a new era in cancer treatment, and cancer immunotherapy continues to be rejuvenated. The clinical goal of cancer immunotherapy is to prime host immune system to provide passive or active immunity against malignant tumors ...
Rui Rui +11 more
doaj +1 more source
Adoptive Immunotherapy in Chimeras with Donor Lymphocytes [PDF]
Acta Haematologica, 2003 Allogeneic stem cell transplantation has a well-defined indication in the treatment of hematological malignancies. The beneficial immune effect of allogeneic marrow transplantation has long been known, but only recently have methods been developed to separate the graft-versus-leukemia (GVL) effect from graft-versus-host disease (GVHD).
Kolb, Hans-Jochem +8 more
openaire +4 more sources
Natural Killer Cells as Allogeneic Effectors in Adoptive Cancer Immunotherapy
Cancers, 2019 Natural killer (NK) cells are attractive within adoptive transfer settings in cancer immunotherapy due to their potential for allogeneic use; their alloreactivity is enhanced under conditions of killer immunoglobulin-like receptor (KIR) mismatch with ...
Kyle B. Lupo, S. Matosevic
semanticscholar +1 more source