Results 41 to 50 of about 3,239,660 (397)
Adoptive T-Cell Transfer to Treat Lymphangioleiomyomatosis
American Journal of Respiratory Cell and Molecular Biology, 2020 Patients with lymphangioleiomyomatosis (LAM) develop pulmonary cysts associated with neoplastic, smooth muscle-like cells that feature neuroendocrine cell markers. The disease preferentially affects premenopausal women. Existing therapeutics do not cure LAM.
Fei Han +10 more
openaire +3 more sources
Pharmaceutics, 2020 Adoptive cell transfer therapy is a promising anti-tumor immunotherapy in which effector immune cells are transferred to patients to treat tumors. However, one of its main limitations is the inefficient trafficking of inoculated effector cells to the ...
Laura Sanz-Ortega +2 more
doaj +1 more source
Viruses, 2021 The viral antigen (Ag)-specific CD8+ cytotoxic T lymphocytes (CTLs) derived from pluripotent stem cells (PSCs), i.e., PSC-CTLs, have the ability to suppress the human immunodeficiency virus (HIV) infection.
Mohammad Haque +8 more
doaj +1 more source
Adoptive cell transfer therapy for hepatocellular carcinoma
Frontiers in Medicine, 2019 Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide. This malignancy is associated with poor prognosis and high mortality. Novel approaches for prolonging the overall survival of patients with advanced HCC are urgently needed.
Renyu Zhang +6 more
semanticscholar +1 more source
iScience, 2023 Summary: Adoptive transfer of hepatitis B virus (HBV) immunity may occur following allogeneic hematopoietic stem cell transplantation (allo-HSCT). Here, we investigated the adoptive transfer of HBV immunity in 112 patients without HBV surface antibody ...
Jinhua Ren +17 more
doaj
Adoptive Cell Transfer: Is it a Promising Immunotherapy for Colorectal Cancer?
Theranostics, 2018 The last decade has witnessed significant advances in the adoptive cell transfer (ACT) technique, which has been appreciated as one of the most promising treatments for patients with cancer.
Jia-qiao Fan +5 more
semanticscholar +1 more source
Receiving, or ‘Adopting’, Donated Embryos to Have Children: Parents Narrate and Draw Kinship Boundaries [PDF]
, 2018 Existing research suggests that embryo donation (ED) may be seen as similar to adoption by those who donate or receive embryos, or it may not. Our qualitative study explored whether having a child via embryo donation initiated kinship connections between
Golombok +12 more
core +3 more sources
Adoptive Transfer of Ceramide Synthase 6 Deficient Splenocytes Reduces the Development of Colitis
Scientific Reports, 2017 Sphingolipids regulate critical cellular processes including inflammation. Ceramide, which serves a central role in sphingolipid metabolism, is generated by six ceramide synthases (CerS) that differ in substrate specificity.
Matthew J. Scheffel +7 more
semanticscholar +1 more source
Targeting fibroblast activation protein in tumor stroma with chimeric antigen receptor T cells can inhibit tumor growth and augment host immunity without severe toxicity. [PDF]
, 2014 The majority of chimeric antigen receptor (CAR) T-cell research has focused on attacking cancer cells. Here, we show that targeting the tumor-promoting, nontransformed stromal cells using CAR T cells may offer several advantages.
Albelda, Steven M. +13 more
core +2 more sources
Journal of Neuroinflammation, 2022 Background Trimethyltin (TMT) is a potent neurotoxicant that leads to hippocampal neurodegeneration. Regulatory T cells (Tregs) play an important role in maintaining the immune balance in the central nervous system (CNS), but their activities are ...
Seon-Young Park +6 more
doaj +1 more source