Beta-Adrenergic Agonists [PDF]
Pharmaceuticals, 2010 Inhaled β2-adrenoceptor (β2-AR) agonists are considered essential bronchodilator drugs in the treatment of bronchial asthma, both as symptoms-relievers and, in combination with inhaled corticosteroids, as disease-controllers.
Giovanni Barisione +3 more
doaj +3 more sources
Functional alteration of the beta-adrenergic receptor during desensitization of mammalian adenylate cyclase by beta-agonists. [PDF]
Proceedings of the National Academy of Sciences, 1984 Exposure of several mammalian cell lines to isoproterenol resulted in a desensitization of the beta-adrenergic receptor-adenylate cyclase system in membranes isolated from the cells. Under the experimental conditions chosen, desensitization was accompanied by a minimal loss of beta-receptors.
S, Kassis, P H, Fishman
openaire +3 more sources
Inverted Variant of Takotsubo Syndrome Caused by Inhaled Adrenergic Beta-2 Agonists [PDF]
European Journal of Case Reports in Internal Medicine, 2018 Takotsubo syndrome (TS) is an acute and reversible clinical syndrome characterized by transient hypokinesis of the left ventricular (LV) apex. Variant forms of LV dysfunction have been reported, including inverted Takotsubo syndrome (ITS), which ...
Marta de Sousa +4 more
doaj +4 more sources
Beta-Adrenergic Receptors and Mechanisms in Asthma: The New Long-Acting Beta-Agonists
Allergology International, 1996 The objective is to review β-adrenergic receptors and mechanisms in the immediate and late bronchial reaction in asthma and the new long-acting β-agonist.
Robert G Townley
doaj +2 more sources
Advancements in Beta-Adrenergic Therapy and Novel Personalised Approach for Portal Hypertension: A Narrative Review [PDF]
LifeLiver cirrhosis is a chronic progressive disease marked by the transition from a compensated to a decompensated stage, associated with severe complications.
Raluca-Ioana Avram +11 more
doaj +2 more sources
Bitter Taste Receptors for Asthma Therapeutics [PDF]
Frontiers in Physiology, 2019 Clinical management of asthma and chronic obstructive pulmonary disease (COPD) has primarily relied on the use of beta 2 adrenergic receptor agonists (bronchodilators) and corticosteroids, and more recently, monoclonal antibody therapies (biologics ...
Ajay P. Nayak +3 more
doaj +3 more sources
In Silico Multitarget Profiling of Non-Selective Beta-Blockers Highlights Their Potential as Key Agents in Breast Cancer Adjuvant Therapy via ADRB2, ERBB2, and NPYR Receptors [PDF]
Current Issues in Molecular BiologyBreast cancer (BC) is associated with multiple molecular factors such as overexpression of the beta-2 adrenergic receptor (ADRB2) and the overproduction of its agonists (norepinephrine and epinephrine).
Felipe Muñoz-González +3 more
doaj +2 more sources
Identifying Ligand Binding Conformations of the β2-Adrenergic Receptor by Using Its Agonists as Computational Probes [PDF]
, 2011 Recently available G-protein coupled receptor (GPCR) structures and biophysical studies suggest that the difference between the effects of various agonists and antagonists cannot be explained by single structures alone, but rather that the conformational
Ashley M. Buckle +64 more
core +12 more sources
Receptor-mediated enhancement of beta adrenergic drug activity by ascorbate in vitro and in vivo. [PDF]
PLoS ONE, 2010 RATIONALE: Previous in vitro research demonstrated that ascorbate enhances potency and duration of activity of agonists binding to alpha 1 adrenergic and histamine receptors.
Patrick F Dillon +4 more
doaj +1 more source
Veterinary Sciences, 2023 Improving beef production efficiency, sustainability, and food security is crucial for meeting the growing global demand for beef while minimizing environmental impact, conserving resources, ensuring economic viability, and promoting animal welfare. Beta-
Alison P. Pfau +7 more
doaj +1 more source