Concerted action of human chorionic gonadotropin and norepinephrine on intracellular-free calcium in human granulosa-lutein cells [PDF]
, 1993 Luteal cells are known to possess receptors for LH/hCG and receptors of the beta-adrenergic type. Interactions of specific agonists with either receptor lead to the activation of adenylate cyclase and subsequently to an increase of cAMP.
Föhr, K. J. +5 more
core +1 more source
Drug Testing and Analysis, EarlyView.Oral administration of salbutamol shows enantioselective disposition in human skeletal muscle, favoring the (S)‐enantiomer with higher relative partitioning of the pharmacologically active (R)‐enantiomer in muscle. This is concerning from an anti‐doping point of view because the anabolic properties demonstrated for salbutamol can potentially be ...
Morten Hostrup +5 more
openalex +2 more sources
β2-adrenergic agonists modulate TNF-α induced astrocytic inflammatory gene expression and brain inflammatory cell populations [PDF]
, 2014 Background: The NF-kappa B signaling pathway orchestrates many of the intricate aspects of neuroinflammation. Astrocytic beta(2)-adrenergic receptors have emerged as potential regulators in central nervous system inflammation and are potential targets ...
Aerts, Joeri L +5 more
core +3 more sources
Prolonged β-Agonist Infusion Does Not Induce Desensitization or Down-Regulation of β-Adrenergic Receptors in Newborn Sheep [PDF]
Pediatric Research, 1992 In adult animals, prolonged beta-agonist exposure leads to down-regulation of beta-adrenergic receptors and desensitization. Prior evidence from our lab suggests that this may not occur in developing animals. To study this, we measured the response to graded epinephrine infusion [2.7, 5.5, 13.6, 27.3 mumol/(kg.min), (0.5, 1.0, 2.5, 5.0 micrograms/(kg ...
Howard Stein +4 more
openaire +3 more sources
Рациональная фармакотерапия в кардиологии, 2022 Aim. To study the structure of antihypertensive drugs prescription in pregnant women in routine practice in Kursk and Chisinau.Material and methods. The study design was observational descriptive cross-sectional.
S. V. Povetkin +6 more
doaj +1 more source
Beta-adrenergic agonists as additive in beef cattle
Boletim de Indústria Animal, 2014 The agonists receptor beta-adrenergic (β-AA) are present in virtually all types of mammalian cells and are stimulated by catecholamines (epinephrine and norepinephrine) produced by the organism itself.
Marcelo Vedovatto +4 more
doaj +1 more source
Adjuvant pharmacological strategies for the musculoskeletal system during long‐term space missions
British Journal of Clinical Pharmacology, EarlyView., 2023 Abstract Despite 2 h of daily exercise training, muscle wasting and bone loss are still present after 6‐month missions to the international space station. Some crew members lose bone much faster than others. In preparation for missions to the Moon and Mars, space agencies are therefore reviewing their countermeasure portfolios.
Friederike Thomasius +2 more
wiley +1 more source
Effects of catecholamines on volemic replacement with saline solution and the impact on heart rate variability in rabbits subjected to hemorrhage. A study by spectral analysis [PDF]
Acta Cirúrgica Brasileira, 2014 PURPOSE: To verify the effects of different catecholamines on volemic expansion and on the autonomic nervous system in rabbits that were subjected to hemorrhage.METHODS: Twenty four rabbits subjected to hemorrhage (with a 25% loss of blood volume) and ...
José Mariano Soares de Moraes +9 more
doaj +1 more source
Beta(2)-adrenergic receptor (ADRB2) gene polymorphisms and risk of COPD exacerbations : the Rotterdam study [PDF]
, 2019 The role of the beta(2)-adrenergic receptor (ADRB2) gene in patients with chronic obstructive pulmonary disease (COPD) is unclear. We investigated the association between ADRB2 variants and the risk of exacerbations in COPD patients treated with inhaled ...
Brusselle, Guy +8 more
core +2 more sources
Trafficking of β2-adrenergic receptors: insulin and β-agonists regulate internalization by distinct cytoskeletal pathways [PDF]
Journal of Cell Science, 2004 Insulin and β-adrenergic agonists stimulate a rapid phosphorylation and sequestration of the β2-adrenergic receptors (β2ARs). Although the expectation was that a common pathway would be involved in the trafficking of the β2AR in response to either hormone, studies reported herein show the existence of unique cytoskeletal requirements for ...
Elena Shumay +3 more
openaire +2 more sources