Results 101 to 110 of about 87,092 (210)

Advanced glycation end-products induce endoplasmic reticulum stress in human aortic endothelial cells [PDF]

, 2013
Background: Advanced glycation end products (AGEs), the final products of the Maillard reaction, have been shown to impair endothelial proliferation and function, thus contributing to endothelial cell injury present in diabetes, inflammatory and ...
Adamopoulos, Christos, Farmaki, Elena, Kiaris, Hippokratis, Papavassiliou, Athanasios G., Piperi, Christina, Spilioti, Eliana   +5 more
core   +1 more source

The role of S100 proteins and their receptor RAGE in pancreatic cancer [PDF]

, 1925
Pancreatic ductal adenocarcinoma (PDAC) is a devastating disease with low survival rates. Current therapeutic treatments have very poor response rates due to the high inherent chemoresistance of the pancreatic-cancer cells.
Leclerc, Estelle, Vetter, Stefan W.
core   +1 more source

Protective role of vitamin B6 (PLP) against DNA damage in Drosophila models of type 2 diabetes [PDF]

, 2018
Growing evidence shows that improper intake of vitamin B6 increases cancer risk and several studies indicate that diabetic patients have a higher risk of developing tumors.
MF Fenech, M Fenech, F Mitelman, A Aguilera, SF Bunting, SJ Duthie, MJ Shrubsole, YI Kim, JB Mason, CD Cantarella, R Percudani, R Percudani, ML Salvo di, H Hellmann, AA Booth, P Bilski, SA Denslow, BN Ames, L Galluzzi, S Mocellin, L Galluzzi, B Gylling, A Marzio, P Kanellis, SC Lee, M Brownlee, D Bonnefont-Rousselot, Y Hinokio, MT Goodarzi, E Tatsch, P Graham, RS Garofalo, RW Alfa, LP Musselman, SN Thompson, R Ugrankar, R Bohni, M Tatar, JM Murillo-Maldonado, M Lorenzi, A Rezabakhsh, SE Polo, JP Madigan, PA Jeggo, C Merigliano, H Vlassara, H Stopper, N Schupp, S Golbidi, EA Muellenbach, J Colombani, AT Haselton, SK Kim, G Lee, EJ Rulifson, SJ Broughton, T Ikeya, M Fraser, S Nakamura, M Pischetsrieder, S Nakamura, J Blasiak, PT Clayton, M Okada, JE Leklem, HJ Ahn, WA Nix, M Gatti, S Bonaccorsi, FJ Diaz-Benjumea   +69 more
core   +2 more sources

Advanced Glycation End Products Evolution after Pancreas-Kidney Transplantation: Plasmatic and Cutaneous Assessments [PDF]

, 2016
Diabetes mellitus leads to increased Advanced Glycation End Products (AGE) production, which has been associated with secondary diabetic complications. Type 1 diabetic patients undergoing pancreas-kidney transplantation (SPKT) can restore normoglycemia ...
Castro-Henriques, A., Fonseca, R., Gouveia, C., Martins, L., Noronha, I., Oliveira, J., Rodrigues, A., Silva, D., Vizcaíno, J.   +8 more
core   +1 more source

Advanced glycation end products

Atherosclerosis, 2016
Patients with peripheral artery disease (PAD) suffer from widespread atherosclerosis. Partly due to the growing awareness of cardiovascular disease, the incidence of PAD has increased considerably during the past decade. It is anticipated that algorithms to identify high risk patients for cardiovascular events require being updated, making use of novel
de Vos, Lisanne C., Lefrandt, Joop D., Dullaart, Robin P. F., Zeebregts, Clark J., Smit, Andries J.   +4 more
openaire   +1 more source

Matrix modification for enhancing the transport properties of the human cartilage endplate to improve disc nutrition. [PDF]

, 2019
Poor solute transport through the cartilage endplate (CEP) impairs disc nutrition and could be a key factor that limits the success of intradiscal biologic therapies.
Dolor, Aaron, Fields, Aaron J, Lazar, Ann A, Lotz, Jeffrey C, Sampson, Sara L, Szoka, Francis C   +5 more
core   +2 more sources

Advanced glycation end-products and bone fractures [PDF]

IBMS BoneKEy, 2009
Bone does not turn over uniformly, and becomes susceptible to post-translational modification by non-enzymatic glycation (NEG). NEG of bone causes the formation of advanced glycation end-products (AGEs) and this process is accelerated with aging, diabetes and antiresorptive postmenopausal osteoporosis therapy.
openaire   +2 more sources

Association between Moraxella keratitis and advanced glycation end products

Scientific Reports
Diabetes mellitus is recognized as a major predisposing factor for Moraxella keratitis. However, how diabetes mellitus contributes to Moraxella keratitis remains unclear.
Hidenori Inoue, Koji Toriyama, Naoko Takahira, Shinobu Murakami, Hitoshi Miyamoto, Takashi Suzuki, Atsushi Shiraishi   +6 more
doaj   +1 more source

The Anti-AGEing and RAGEing Potential of Isothiocyanates

Molecules
Isothiocyanates (ITCs), found in edible plants such as cruciferous vegetables, are a group of reactive organo-sulfur phytochemicals produced by the hydrolysis of precursors known as glucosinolates.
Bradley A. Krisanits, Bhoomika Kaur, Jed W. Fahey, David P. Turner   +3 more
doaj   +1 more source

Targeting the AGEs-RAGE axis: pathogenic mechanisms and therapeutic interventions in diabetic wound healing

Frontiers in Medicine
Diabetes is a global health problem, with diabetic wounds constituting one of its most severe complications. Advanced glycation end products (AGEs) and their receptor, the receptor for advanced glycation end products (RAGE), play a key role in the ...
Haohui Lin, Yi Yang, Xia Wang, Manhon Chung, Li Zhang, Sa Cai, Xiaohua Pan, Yu Pan   +7 more
doaj   +1 more source