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Advanced glycation end products and diabetic retinopathy [PDF]
Journal of Ocular Biology, Diseases, and Informatics, 2012 Studies have established hyperglycemia as the most important factor in the progress of vascular complications. Formation of advanced glycation end products (AGEs) correlates with glycemic control. The AGE hypothesis proposes that hyperglycemia contributes to the pathogenesis of diabetic complications including retinopathy.
Yashodhara, Sharma +4 more
openaire +2 more sources
Journal of the Formosan Medical Association, 2021 Background/Purpose: Periodontal disease and diabetes mellitus (DM) are both chronic inflammatory and highly prevalent diseases. A large amount of evidence suggested that the accumulation of oxidative stress plays a significant role in the deterioration ...
Chia-Ming Liu +5 more
doaj +1 more source
Prevention of Protein Glycation by Natural Compounds [PDF]
, 2015 Non-enzymatic protein glycosylation (glycation) contributes to many diseases and aging of organisms. It can be expected that inhibition of glycation may prolong the lifespan.
Bartosz, Grzegorz +1 more
core +2 more sources
International Archives of Otorhinolaryngology, 2016 Introduction High mobility group box 1 is a versatile protein involved in gene transcription, extracellular signaling, and response to inflammation. Extracellularly, high mobility group box 1 binds to several receptors, notably the receptor for advanced ...
Austin Nguyen +4 more
doaj +1 more source
The Role of Advanced Glycation End Products on Dyslipidemia
Metabolites, 2023 Disorders of lipoprotein metabolism and glucose homeostasis are common consequences of insulin resistance and usually co-segregate in patients with metabolic syndrome and type 2 diabetes mellitus (DM).
Jelena Vekic +8 more
doaj +1 more source
Advanced glycation end products modulate transcriptional regulation in mesangial cells [PDF]
, 1996 Advanced glycation end products modulate transcriptional regulation in mesangial cells. Advanced glycation end products (AGEs) stimulate synthesis of extracellular matrix (ECM) in a receptor-mediated manner on mesangial cells.
Iehara, Noriyuki +4 more
core +1 more source
Advanced Glycation End Products and Diabetic Complications [PDF]
The Korean Journal of Physiology & Pharmacology, 2014 During long standing hyperglycaemic state in diabetes mellitus, glucose forms covalent adducts with the plasma proteins through a non-enzymatic process known as glycation. Protein glycation and formation of advanced glycation end products (AGEs) play an important role in the pathogenesis of diabetic complications like retinopathy, nephropathy ...
Singh, Varun Parkash +3 more
openaire +2 more sources
Dietary interventions to contrast the onset and progression of diabetic nephropathy. a critical survey of new data [PDF]
, 2017 This article is a critical overview of recent contributions on the dietary corrections and the foods that have been claimed to delay or hinder the onset of diabetic nephropathy (DN) and its progression to end-stage renal disease.
Iacobini, Carla +3 more
core +1 more source
A new gender-specific model for skin autofluorescence risk stratification [PDF]
, 2015 Advanced glycation endproducts (AGEs) are believed to play a significant role in the pathophysiology of a variety of diseases including diabetes and cardiovascular diseases.
Ahmad, MS +4 more
core +1 more source
BMC Musculoskeletal Disorders, 2010 Background Levels of pentosidine (representative of advanced glycation end-products) in sera of patients with rheumatoid arthritis are increased when compared with sera of other diagnoses or healthy controls.
Vilím Vladimír +2 more
doaj +1 more source