Results 1 to 10 of about 81,199 (355)

Association of accumulated advanced glycation end‐products with a high prevalence of sarcopenia and dynapenia in patients with type 2 diabetes

open access: yesJournal of Diabetes Investigation, 2019
Aims/Introduction Advanced glycation end‐products (AGEs), which are a major cause of diabetic vascular complications, accumulate in various tissues under chronic hyperglycemic conditions, as well as with aging in patients with diabetes.
Hiroyasu Mori   +14 more
doaj   +1 more source

Advanced Glycation End Products (AGEs) May Be a Striking Link Between Modern Diet and Health

open access: yesBiomolecules, 2019
The Maillard reaction is a simple but ubiquitous reaction that occurs both in vivo and ex vivo during the cooking or processing of foods under high-temperature conditions, such as baking, frying, or grilling. Glycation of proteins is a post-translational
Vidhu Gill   +4 more
semanticscholar   +1 more source

Association of advanced glycation end products with sarcopenia and frailty in chronic kidney disease

open access: yesScientific Reports, 2020
Prevalence of sarcopenia is high in patients with chronic kidney disease (CKD), especially in those with dialysis. Various pathological conditions related to CKD, such as chronic inflammation, insulin resistance, and endothelial dysfunction, are thought ...
J. Yabuuchi   +11 more
semanticscholar   +1 more source

Advanced Glycation End Products: Building on the Concept of the "Common Soil" in Metabolic Disease.

open access: yesEndocrinology, 2019
The role of advanced glycation end products (AGEs) in promoting and/or exacerbating metabolic dysregulation is being increasingly recognized. AGEs are formed when reducing sugars non-enzymatically bind to proteins or lipids, a process that is enhanced by
Henry H. Ruiz, R. Ramasamy, A. Schmidt
semanticscholar   +1 more source

Advanced glycation end products inhibit the osteogenic differentiation potential of adipose‐derived stem cells by modulating Wnt/β‐catenin signalling pathway via DNA methylation

open access: yesCell Proliferation, 2020
Advanced glycation end products (AGEs) are considered a cause of diabetic osteoporosis. Although adipose‐derived stem cells (ASCs) are widely used in the research of bone regeneration, the mechanisms of the osteogenic differentiation of ASCs from ...
Yong Li   +7 more
semanticscholar   +1 more source

Involvement of Advanced Glycation End Products in the Pathogenesis of Diabetic Retinopathy

open access: yesCellular Physiology and Biochemistry, 2018
Diabetic retinopathy (DR) is a common and devastating microvascular complication of diabetes and a major cause of acquired blindness in young adults. Advanced glycation end products (AGEs) accumulated under hyperglycemic conditions are thought to play an
Jing Xu   +6 more
semanticscholar   +1 more source

Receptor for Advanced Glycation End Products Acts as a Fuel to Colorectal Cancer Development

open access: yesFrontiers in Oncology, 2020
Receptor for advanced glycation end-products (RAGE) is a multiligand binding and single-pass transmembrane protein taken in diverse chronic inflammatory conditions.
Fatemeh Azizian-Farsani   +5 more
semanticscholar   +1 more source

Skin Autofluorescence–Indicated Advanced Glycation End Products as Predictors of Cardiovascular and All‐Cause Mortality in High‐Risk Subjects: A Systematic Review and Meta‐analysis

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Background Chronic deposits of advanced glycation end products produced by enzymatic glycation have been suggested as predictors of atherosclerotic‐related disorders.
Ivan Cavero‐Redondo   +7 more
doaj   +1 more source

Development and Progression of Non-Alcoholic Fatty Liver Disease: The Role of Advanced Glycation End Products

open access: yesInternational Journal of Molecular Sciences, 2019
Non-alcoholic fatty liver disease (NAFLD) affects up to 30% of the adult population and is now a major cause of liver disease-related premature illness and deaths in the world.
Dinali H Fernando   +3 more
semanticscholar   +1 more source

Receptor of advanced glycation end products and cardiovascular risk in elderly with type 2 diabetes mellitus

open access: yesJournal of Biological Research, 2018
The interaction of Advanced Glycation End products (AGEs) and their specific receptor, Receptor for Advanced Glycation End products (RAGE) play an important role in diabetes and vascular complications.
Claudia Borsa   +4 more
doaj   +1 more source

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