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Endogenous advanced glycation end products in the pathogenesis of chronic diabetic complications
Frontiers in Molecular Biosciences, 2022 Diabetes is a common metabolic illness characterized by hyperglycemia and is linked to long-term vascular problems that can impair the kidney, eyes, nerves, and blood vessels.
Misganaw Asmamaw Mengstie +7 more
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Advanced Glycation End Products and Psoriasis
Vaccines, 2023 Advanced glycation end products (AGEs) are biologically active compounds formed physiologically throughout a sequence of chemical reactions, to generate highly oxidant-reactive aldehydes that combine covalently to proteins.
Martina Maurelli +2 more
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Advanced Glycation End Products in Health and Disease
Microorganisms, 2022 Advanced glycation end products (AGEs), formed through the nonenzymatic reaction of reducing sugars with the side-chain amino groups of lysine or arginine of proteins, followed by further glycoxidation reactions under oxidative stress conditions, are ...
V. Prakash Reddy +2 more
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The Role of Advanced Glycation End Products in Diabetic Vascular Complications [PDF]
Diabetes & Metabolism Journal, 2018 In cases of chronic hyperglycemia, advanced glycation end-products (AGEs) are actively produced and accumulated in the circulating blood and various tissues.
Sang Youl Rhee, Young Seol Kim
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Advanced Glycation End-Products in Skeletal Muscle Aging
Bioengineering, 2021 Advanced age causes skeletal muscle to undergo deleterious changes including muscle atrophy, fast-to-slow muscle fiber transition, and an increase in collagenous material that culminates in the age-dependent muscle wasting disease known as sarcopenia ...
Lucas C. Olson +4 more
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Sex-specific differences of advanced glycation end products in diabetes [PDF]
Nutrition & DiabetesAdvanced glycation end products (AGEs) are formed through non-enzymatic glycation reactions and accumulate in tissues, particularly under pathological conditions such as diabetes mellitus.
Michael Hellwig +5 more
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Role of advanced glycation end products in cellular signaling
Redox Biology, 2014 Improvements in health care and lifestyle have led to an elevated lifespan and increased focus on age-associated diseases, such as neurodegeneration, cardiovascular disease, frailty and arteriosclerosis.
Christiane Ott +5 more
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Effects of advanced glycation end products on stem cell [PDF]
Frontiers in Cell and Developmental BiologyIn recent years, stem cell therapy has become a pivotal component of regenerative medicine. Stem cells, characterized by their self-renewal capacity and multidirectional differentiation potential, can be isolated from a variety of biological tissues ...
Zetai Zheng +6 more
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Біологічні студії, 2021 Background. Diabetes mellitus intensifies non-enzymatic glycosylation (glycation) of biomolecules under conditions of chronic hyperglycemia and facilitates accumulation of advanced glycation end products.
Kh. Ye. Furtak +2 more
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Advanced Glycation End Products and Diabetes Mellitus: Mechanisms and Perspectives
Biomolecules, 2022 Persistent hyperglycemic state in type 2 diabetes mellitus leads to the initiation and progression of non-enzymatic glycation reaction with proteins and lipids and nucleic acids.
Mariyam Khalid, G. Petroianu, A. Adem
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