Results 31 to 40 of about 58,432 (298)

Advanced glycation end products, galectin-3, matrix metalloproteinase-9 activity in men with heart failure and concomitant benign prostatic hyperplasia with androgen deficiency

Medičnì Perspektivi, 2021
The aim was to evaluate serum levels of matrix metalloproteinases-9 activity, advanced glycation end products, galectin-3, C-reactive protein in men with heart failure and benign prostatic hyperplasiawith testosterone deficiency.
V.S. Nedzvetsky, O.Yu. Sirenko, V.A. Tkachenko, O.V. Kuryata   +3 more
doaj   +1 more source

Predictive ability of serum advanced glycation end products at 11 to 13 weeks of gestation for early-onset preeclampsiaAJOG Global Reports at a Glance

AJOG Global Reports, 2022
BACKGROUND: Placental hypoxia and resultant oxidative stress have been associated with the development of preeclampsia. Oxidative stress promotes the formation of advanced glycation end products. OBJECTIVE: This study aimed to assess whether serum levels
Minako Goto, MD, Sho-ichi Yamagishi, MD, Takanori Matsui, PhD, Keiko Koide, MD, Hiroko Takita, MD, Mayumi Tokunaka, MD, Akihiko Sekizawa, MD   +6 more
doaj   +1 more source

A comparative study of sulphated polysaccharide effects on advanced glycation end-product uptake and scavenger receptor class A level in macrophages

Diabetes & Vascular Disease Research, 2020
Advanced glycation end-products, especially toxic advanced glycation end-products derived from glyceraldehyde (advanced glycation end-product-2) and glycolaldehyde (advanced glycation end-product-3), are biologically reactive compounds associated with ...
Takashi Nishinaka, Shuji Mori, Yui Yamazaki, Atsuko Niwa, Hidenori Wake, Tadashi Yoshino, Masahiro Nishibori, Hideo Takahashi   +7 more
doaj   +1 more source

Expression of advanced glycation end products and receptors in gingival tissues of patients with noninsulin-dependent diabetes mellitus-associated periodontitis

Journal of Dental Sciences, 2023
Background/purpose: Advanced glycation end products (AGEs) are known to accumulate in the periodontal tissues of patients with diabetes mellitus (DM). Through this study, we aimed to investigate the distribution of AGEs and the receptor of AGEs (RAGE) in
Ya-Han Chang, Chen-Ling Huang, An-Tsz Hsieh, Chia-Ai Jao, Hsein-Kun Lu   +4 more
doaj   +1 more source

Association between advanced glycation end products and impaired fasting glucose : results from the SALIA study [PDF]

, 2015
Advanced glycation end products (AGEs) may contribute to the development of type 2 diabetes and related complications, whereas their role in the early deterioration of glycaemia is unknown.
Annette Peßler, Thomas Henle, Vierkötter, Andrea, Roden, Michael, Juliane Freund, Ursula Krämer, Schulte, Thomas, Michael Hellwig, Tamara Schikowski, Mohammad Vossoughi, Christian Luckhaus, Christian Herder, Tom Teichert, Luckhaus, Christian, Vossoughi, Mohammad, Thomas Schulte, Barbara Hoffmann, Schikowski, Tamara, Krämer, Ursula, Sugiri, Dorothea, Dorothea Sugiri, Hoffmann, Barbara, Hellwig, Michael, Anne Hellwig, Andrea Vierkötter, Henle, Thomas, Michael Roden, Freund, Juliane, Teichert, Tom, Hellwig, Anne, Peßler, Annette, Herder, Christian   +31 more
core   +1 more source

Advanced Glycation End Products and Receptor for Advanced Glycation End Products in AA Amyloidosis

The American Journal of Pathology, 2003
Advanced glycation end products (AGEs) may be involved in either amyloidogenesis or complications related to amyloid. We hypothesized that AGEs may influence the pathogenesis of AA amyloidosis, and investigated the spatial and temporal relationship between AGEs, carboxy methyl lysine (CML), the AGE receptor (RAGE), and AA amyloid in humans and mice ...
Christoph, Röcken, Rosemarie, Kientsch-Engel, Sophie, Mansfeld, Barbara, Stix, Kay, Stubenrauch, Bernd, Weigle, Frank, Bühling, Mona, Schwan, Wolfgang, Saeger   +8 more
openaire   +3 more sources

Advanced Glycation End Products, Soluble Receptor for Advanced Glycation End Products, and Risk of Colorectal Cancer [PDF]

Cancer Epidemiology, Biomarkers & Prevention, 2011
Abstract Background: Advanced glycation end products (AGE) accumulate in human tissue proteins during aging, particularly under hyperglycemia conditions. AGEs induce oxidative stress and inflammation via the receptor for AGEs (RAGE) and soluble RAGE (sRAGE) can neutralize the effects mediated by RAGE–ligand engagement ...
Li, Jiao, Philip R, Taylor, Stephanie J, Weinstein, Barry I, Graubard, Jarmo, Virtamo, Demetrius, Albanes, Rachael Z, Stolzenberg-Solomon   +6 more
openaire   +2 more sources

The critical role of methylglyoxal and glyoxalase 1 in diabetic nephropathy [PDF]

, 2014
The discovery of increased formation of methylglyoxal (MG) by cell metabolism in high glucose concentration in vitro suggested possible relevance to diabetes and diabetes complications (1,2).
Rabbani, Naila, Thornalley, Paul J.
core   +1 more source

A novel monoclonal antibody targeting carboxymethyllysine, an advanced glycation end product in atherosclerosis and pancreatic cancer. [PDF]

PLoS ONE, 2018
Advanced glycation end products are formed by non-enzymatic reactions between proteins and carbohydrates, causing irreversible lysine and arginine alterations that severely affect protein structure and function.
Ulrika Wendel, Nina Persson, Christian Risinger, Eva Bengtsson, Björn Nodin, Lena Danielsson, Charlotte Welinder, Gunilla Nordin Fredrikson, Bo Jansson, Ola Blixt   +9 more
doaj   +1 more source

Non-enzymatic glycoxidation linked with nutrition enhances the tumorigenic capacity of prostate cancer epithelia through AGE mediated activation of RAGE in cancer associated fibroblasts

Translational Oncology, 2022
The molecular implications of food consumption on cancer etiology are poorly defined. The rate of nutrition associated non-enzymatic glycoxidation, a reaction that occurs between reactive carbonyl groups on linear sugars and nucleophilic amino, lysyl and
Bradley A. Krisanits, Pamela Woods, Lourdes M. Nogueira, Demarcus D. Woolfork, Courtney E. Lloyd, Andrew Baldwin, Callan C. Frye, Kendell D. Peterson, Sean D. Cosh, Qi-Jin Guo, Laura S. Spruill, Michael B. Lilly, Kristi Helke, Hong Li, George S. Hanna, Mark T. Hamann, Courtney Thomas, Mahtabuddin Ahmed, Monika B. Gooz, Victoria J. Findlay, David P. Turner   +20 more
doaj   +1 more source