Results 41 to 50 of about 58,432 (298)
Serum levels of advanced glycation endproducts and other markers of protein damage in early diabetic nephropathy in type 1 diabetes [PDF]
Objective To determine the role of markers of plasma protein damage by glycation, oxidation and nitration in microalbuminuria onset or subsequent decline of glomerular filtration rate (termed “early GFR decline”) in patients with type 1 diabetes ...
Weston Andrew +35 more
core +1 more source
Zinc against advanced glycation end products [PDF]
SummaryAdvanced glycation end products (AGEs) are destructive compounds with pathogenic importance in age‐related chronic diseases. Zinc has antioxidant, anti‐inflammatory and anti‐apoptotic potential. This study aimed to summarize effects of zinc onAGEformation andAGE‐induced damaging agents.
Sorayya Kheirouri +2 more
openaire +2 more sources
Leukocytes in type 1 diabetes mellitus: the changes they undergo and induce
As leukocytes represent cellular and humoral immunity at the same time, they are a vital part of every immune process. This also stands for autoimmune processes and disorders, such as diabetes, specifically type 1 diabetes mellitus.
О. М. Kuchurka +4 more
doaj +1 more source
Advanced Glycation End-Products in Skeletal Muscle Aging
Advanced age causes skeletal muscle to undergo deleterious changes including muscle atrophy, fast-to-slow muscle fiber transition, and an increase in collagenous material that culminates in the age-dependent muscle wasting disease known as sarcopenia ...
Lucas C. Olson +4 more
doaj +1 more source
This record contains raw data related to the article "Modulation of soluble receptor for advanced glycation end products isoforms and advanced glycation end products in long-living individuals" Background: Circulating levels of soluble receptor for ...
Raucci Angela
core +1 more source
Advanced Glycation End Products and Diabetic Complications [PDF]
During long standing hyperglycaemic state in diabetes mellitus, glucose forms covalent adducts with the plasma proteins through a non-enzymatic process known as glycation. Protein glycation and formation of advanced glycation end products (AGEs) play an important role in the pathogenesis of diabetic complications like retinopathy, nephropathy ...
Singh, Varun Parkash +3 more
openaire +2 more sources
Differential effects of glyoxalase 1 overexpression on diabetic atherosclerosis and renal dysfunction in streptozotocin-treated, apolipoprotein E-deficient mice [PDF]
The reactive dicarbonyls, glyoxal and methylglyoxal (MG), increase in diabetes and may participate in the development of diabetic complications. Glyoxal and MG are detoxified by the sequential activities of glyoxalase 1 (GLO1) and glyoxalase 2.
Rabbani, Naila +11 more
core +1 more source
Glycation is a non-enzymatic biochemical reaction between reducing sugars and amino acids, causing the crosslinking and rearrangement of glycated proteins, leading to irreversible formation of Advanced Glycation End products (AGEs).
Alpana Pande +4 more
doaj +1 more source
Advanced glycation end products [PDF]
Aging is the progressive accumulation of damage to an organism over time leading to disease and death. Aging research has been very intensive in the last years aiming at characterizing the pathophysiology of aging and finding possibilities to fight age-related diseases. Various theories of aging have been proposed.
Gkogkolou, Paraskevi, Böhm, Markus
openaire +2 more sources
Background/Purpose: Periodontal disease and diabetes mellitus (DM) are both chronic inflammatory and highly prevalent diseases. A large amount of evidence suggested that the accumulation of oxidative stress plays a significant role in the deterioration ...
Chia-Ming Liu +5 more
doaj +1 more source

