Results 151 to 160 of about 58,432 (298)

Assessment of Oral Glycine and Lysine Therapy on Receptor for Advanced Glycation End Products and Transforming Growth Factor Beta Expression in the Kidney of Streptozotocin-Induced Diabetic Rats in Comparison with Normal Rats [PDF]

open access: yesJournal of Kerman University of Medical Sciences, 2014
Background & Aims: Today, diabetic nephropathy is considered to be one of the most common causes of end stage renal disease. Uncontrolled hyperglycemia, and consequently, production of advanced glycation end products activate pathways which play key ...
Somayeh Sadat Heidary   +3 more
doaj  

Inhibition of protein glycation and advanced glycation end products by ascorbic acid

open access: yes, 2016
Advanced glycation end products (AGEs) formation is increased in diabetes mellitus, leading to microvascular and macrovascular complications. Recently, much attention has been focused on natural and synthetic inhibitors to delay the onset or progression ...
Zafar, Hira   +3 more
core   +1 more source

Staging concept for aging management: Definition, mechanism, and coping strategies

open access: yesVIEW, EarlyView.
We divided the overall aging stage into “pre‐aging”, “aging compensation”, and “aging disability”. For each stage, we delineate the clinical presentations, biological phenomena, theoretical underpinnings, and key management priorities. Abstract Aging, as a gradual and largely irreversible biological process, characterized by declining organismal ...
Zhonghan Wang   +6 more
wiley   +1 more source

Targeting the AGEs-RAGE axis: pathogenic mechanisms and therapeutic interventions in diabetic wound healing

open access: yesFrontiers in Medicine
Diabetes is a global health problem, with diabetic wounds constituting one of its most severe complications. Advanced glycation end products (AGEs) and their receptor, the receptor for advanced glycation end products (RAGE), play a key role in the ...
Haohui Lin   +7 more
doaj   +1 more source

Preparation of advanced glycation end products in vitro [PDF]

open access: yesNephrology Dialysis Transplantation, 2007
Waanders, Femke   +4 more
openaire   +2 more sources

Interaction of receptor for advanced glycation end products with advanced oxidation protein products induces podocyte injury

open access: yes, 2012
Chronic kidney disease (CKD) is characterized by progressive decline in renal function. Podocyte dropouts contribute to the pathogenesis of diabetic and nondiabetic CKD.
Yamamoto, Yasuhiko, Yamamoto, Hiroshi
core   +1 more source

Biomarkers to predict outcomes in diabetic foot ulcers

open access: yesVIEW, EarlyView.
Studies attempting to predict the healing outcome of diabetic foot ulcers (DFUs) have investigated various biological materials and recovered molecules that may aid in discriminating wounds that will heal and those that will not heal. This graphical abstract captures the commonly studied classes of biomarkers in the context of DFUs.
Julie Okiro   +6 more
wiley   +1 more source

Microbiome–Metabolomics Analysis of the Impacts of Long-Term Dietary Advanced-Glycation-End-Product Consumption on C57BL/6 Mouse Fecal Microbiota and Metabolites

open access: yes, 2018
Thermally processed diets are widely consumed, although advanced-glycation end products (AGEs) are unavoidably formed. AGEs, clusters of protein-cross-linking products, become less digestible because they impair intestinal peptidase proteolysis.
Shanchun Yang (5600822)   +19 more
core   +1 more source

TcALS knockdown accelerates metamorphosis via insulin signaling in Tribolium castaneum

open access: yesInsect Science, EarlyView.
RNAi silencing of TcALS accelerates larva‐to‐pupa metamorphosis in Tribolium castaneum. Abstract Insect metamorphosis is an evolutionary adaptation precisely regulated by nutritional and hormonal cues. The red flour beetle Tribolium castaneum, a major stored‐product pest, serves as an excellent model for studying this process.
Min Li   +8 more
wiley   +1 more source

AKTIVITAS ANTIFOTOOKSIDASI DAN PENGHAMBATAN PEMBENTUKKAN AGEs (ADVANCED GLYCATION END PRODUCTS) EKSTRAK KULIT BUAH PISANG GOROHO (Musa acuminate)

open access: yes, 2018
AKTIVITAS ANTIFOTOOKSIDASI DAN PENGHAMBATAN PEMBENTUKKAN AGEs (ADVANCED GLYCATION END PRODUCTS) EKSTRAK KULIT BUAH PISANG GOROHO (Musa acuminate)Jane Beatrix Rety Kowaas1), Edi Suryanto2), Defny Silvia Wewengkang3)1)Program studi Farmasi FMIPA Unsrat ...
Kowaas, Jane B.R.
core   +1 more source

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