Results 171 to 180 of about 51,328 (260)

Advanced Glycation End Products and Genetic Polymorphism in the Pathogenesis of Microvascular Complications in Type 2 Diabetes Mellitus: A Narrative Review. [PDF]

Cureus
Sarangi R, Singh S, Sahoo JP, Satpathy A.   +3 more
europepmc   +1 more source

Causal Effects of Type 2 Diabetes Mellitus on Chronic Periodontitis and the Mediating Role of Oxidative Stress: Evidence From Mendelian Randomization and Mediation Analysis

Oral Diseases, EarlyView.
ABSTRACT Background Type 2 diabetes mellitus (T2DM) is associated with an increased risk of chronic periodontitis, but genetic evidence and oxidative stress‐related pathways remain unclear. Objective This study assessed the genetically inferred association between T2DM and chronic periodontitis, evaluated oxidative stress biomarkers as potential ...
Mengjie Kong, James Kit Hon Tsoi, Kang Li, Cynthia Kar Yung Yiu   +3 more
wiley   +1 more source

Serum advanced glycation end-products as a biomarker of cumulative glycaemic burden and complications in type 2 diabetes: a pilot study. [PDF]

Ann Med
Lin X, Lv D, Meng W, Wang P, Zhang X.
europepmc   +1 more source

Periodontal Therapy–Related Changes in Clinical Parameters, Active‐Matrix Metalloproteinase‐8 and C‐Reactive Protein in Prediabetes and Diabetes

Oral Diseases, EarlyView.
ABSTRACT Objectives This study investigated the effect of nonsurgical periodontal therapy (NSPT) on periodontal clinical parameters, active‐matrix metalloproteinase‐8 (aMMP‐8), high sensitivity C‐reactive protein (hsCRP), and glycated hemoglobin (HbA1c), and their relationships in diabetes and prediabetes patients with periodontitis.
Kehinde Adesola Umeizudike, Olayiwola Ibrahim Olaoye, Ayodele Charles Ogundana, Ismo T. Räisänen, Solomon Olusegun Nwhator, Babatunde Yusuf Alli, Patricia Omowunmi Ayanbadejo, Olufemi Adetola Fasanmade, Timo Sorsa   +8 more
wiley   +1 more source

Serum-Soluble Receptor for Advanced Glycation End Products as a Potential Biomarker in Lung Cancer Patients. [PDF]

J Pers Med
Panagiotou E, Georganta A, Garoflos E, Karaviti E, Karaviti D, Kontogiannis A, Chorianopoulou S, Kotteas E, Syrigos N, Peppa M.   +9 more
europepmc   +1 more source

Osteoarthritis Therapeutics: From Microenvironment Understanding to Regenerative Intervention—Current Advances and Future Perspectives

Orthopaedic Surgery, EarlyView.
This article outlines a paradigm shift in OA therapeutics, OA as a systemic disease of joint microenvironment imbalance. It synthesizes advances in targeting key pathological hubs—immune, metabolic, and senescent—and details novel regenerative strategies using engineered biomaterials and exosomes.
Yongbiao Meng, Shenghua Wu, Quanchun Liu
wiley   +1 more source

Potential for anti‑angiogenic therapy targeting the receptor for advanced glycation end products/VEGF axis in ulcerative colitis (Review). [PDF]

Mol Med Rep
Xu C, Li Y, Hong Y, Zhou D, He K, Wang L, Hong F.   +6 more
europepmc   +1 more source

Artificial Intelligence‐Driven Precision Bisphosphonate Therapy in Osteoporosis: Mechanisms, Clinical Applications, Risks, and Future Directions

Orthopaedic Surgery, EarlyView.
This comprehensive review integrates 17 benchmark studies to illustrate the transition of osteoporosis management toward precision medicine. The schematic highlights three key clinical applications: AI‐driven opportunistic screening from routine CTs, precision pharmacotherapy selection, and the predictive prevention of adverse events like MRONJ ...
Xiang Yao, Yicong Chao, Xiao Gu, Jingtao Peng, Jishan Yuan, Wei Shi, Fuguo Zhang, Qiwen Bao   +7 more
wiley   +1 more source

Association Between Advanced Glycation End-Products and Adherence to the Mediterranean Diet in Individuals with Type 2 Diabetes Mellitus: A Cross-Sectional Study. [PDF]

Nutrients
Patsiliva M, Theodorakopoulou A, Stergioti A, Rebelos E, Liberopoulos E, Anastasiou IA, Tentolouris N.   +6 more
europepmc   +1 more source

Advanced glycation end-products exacerbate myocardial ischemia/reperfusion injury by promoting mitochondrial oxidative damage and PANoptosis in diabetes mellitus. [PDF]

Redox Biol
Yang J, Zhang J, Huang R, Meng K, Liang J, Lin J, Wang J, Wang Y, Gao Y, Qu Y, Hu S, Cao J, Su H, Zhang F, Ge J.   +14 more
europepmc   +1 more source