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Advanced Glycation End Products in Health and Disease
Microorganisms, 2022 Advanced glycation end products (AGEs), formed through the nonenzymatic reaction of reducing sugars with the side-chain amino groups of lysine or arginine of proteins, followed by further glycoxidation reactions under oxidative stress conditions, are ...
V. Prakash Reddy +2 more
doaj +4 more sources
Advanced glycation end-products: a review [PDF]
Diabetologia, 2001 Advanced glycation end-products are a complex and heterogeneous group of compounds that have been implicated in diabetes related complications. At present it is not known if they are the cause or the consequence of the complications observed. We discuss the chemistry of advanced glycated end-product formation and their patho-biochemistry particularly ...
R. Singh +3 more
semanticscholar +4 more sources
Endogenous advanced glycation end products in the pathogenesis of chronic diabetic complications
Frontiers in Molecular Biosciences, 2022 Diabetes is a common metabolic illness characterized by hyperglycemia and is linked to long-term vascular problems that can impair the kidney, eyes, nerves, and blood vessels.
Misganaw Asmamaw Mengstie +7 more
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Advanced Glycation End Products and Psoriasis
Vaccines, 2023 Advanced glycation end products (AGEs) are biologically active compounds formed physiologically throughout a sequence of chemical reactions, to generate highly oxidant-reactive aldehydes that combine covalently to proteins.
Martina Maurelli +2 more
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Advanced Glycation End Products and Diabetic Complications [PDF]
The Korean Journal of Physiology & Pharmacology, 2014 During long standing hyperglycaemic state in diabetes mellitus, glucose forms covalent adducts with the plasma proteins through a non-enzymatic process known as glycation.
Varun Singh +3 more
semanticscholar +4 more sources
Toxicity of advanced glycation end products (Review)
Biomedical Reports, 2021 Advanced glycation end-products (AGEs) are proteins or lipids glycated nonenzymatically by glucose, or other reducing sugars and their derivatives, such as glyceraldehyde, glycolaldehyde, methyloglyoxal and acetaldehyde.
Aleksandra Kuzan
semanticscholar +6 more sources
The Role of Advanced Glycation End Products on Dyslipidemia [PDF]
Metabolites, 2023 Disorders of lipoprotein metabolism and glucose homeostasis are common consequences of insulin resistance and usually co-segregate in patients with metabolic syndrome and type 2 diabetes mellitus (DM).
Jelena Vekic +8 more
doaj +5 more sources
The Role of Advanced Glycation End Products in Diabetic Vascular Complications [PDF]
Diabetes & Metabolism Journal, 2018 In cases of chronic hyperglycemia, advanced glycation end-products (AGEs) are actively produced and accumulated in the circulating blood and various tissues.
Sang Youl Rhee, Young Seol Kim
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Advanced Glycation End-Products in Skeletal Muscle Aging
Bioengineering, 2021 Advanced age causes skeletal muscle to undergo deleterious changes including muscle atrophy, fast-to-slow muscle fiber transition, and an increase in collagenous material that culminates in the age-dependent muscle wasting disease known as sarcopenia ...
Lucas C. Olson +4 more
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Sex-specific differences of advanced glycation end products in diabetes [PDF]
Nutrition & DiabetesAdvanced glycation end products (AGEs) are formed through non-enzymatic glycation reactions and accumulate in tissues, particularly under pathological conditions such as diabetes mellitus.
Michael Hellwig +5 more
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