Results 21 to 30 of about 116,589 (255)
Advanced glycation end products: sparking the development of diabetic vascular injury.
Circulation, 2006 Advanced glycation end products (AGEs) are proteins or lipids that become glycated after exposure to sugars. AGEs are prevalent in the diabetic vasculature and contribute to the development of atherosclerosis. The presence and accumulation of AGEs in many different cell types affect extracellular and intracellular structure and function.
Alison H. Goldin +3 more
semanticscholar +3 more sources
Frontiers in Medicine, 2022 Advanced glycation end products (AGEs) are a series of stable compounds produced under non-enzymatic conditions by the amino groups of biomacromolecules and the free carbonyl groups of glucose or other reducing sugars commonly produced by thermally ...
Chun-yu Chen +7 more
semanticscholar +1 more source
Experimental and Molecular Medicine, 2021 Advanced glycation end products (AGEs) are potentially harmful and heterogeneous molecules derived from nonenzymatic glycation. The pathological implications of AGEs are ascribed to their ability to promote oxidative stress, inflammation, and apoptosis ...
W. Rungratanawanich +4 more
semanticscholar +1 more source
AJOG Global Reports, 2022 BACKGROUND: Placental hypoxia and resultant oxidative stress have been associated with the development of preeclampsia. Oxidative stress promotes the formation of advanced glycation end products. OBJECTIVE: This study aimed to assess whether serum levels
Minako Goto, MD +6 more
doaj +1 more source
Zinc against advanced glycation end products [PDF]
Clinical and Experimental Pharmacology and Physiology, 2018 SummaryAdvanced glycation end products (AGEs) are destructive compounds with pathogenic importance in age‐related chronic diseases. Zinc has antioxidant, anti‐inflammatory and anti‐apoptotic potential. This study aimed to summarize effects of zinc onAGEformation andAGE‐induced damaging agents.
Sorayya Kheirouri +2 more
openaire +2 more sources
Advanced glycation end products are associated with pulse pressure in type 1 diabetes: the EURODIAB Prospective Complications Study [PDF]
, 2005 We investigated the associations of pulse pressure (a measure of arterial stiffness) with the early glycation products hemoglobin A1c (HbA1c) and Amadori albumin and the advanced glycation end products pentosidine, Nepsilon-(carboxymethyl)lysine and ...
Bootsma, A.H. +5 more
core +7 more sources
Advanced Glycation End-Products and Diabetic Neuropathy of the Retina
International Journal of Molecular Sciences, 2023 Diabetic retinopathy is a tissue-specific neurovascular impairment of the retina in patients with both type 1 and type 2 diabetes. Several pathological factors are involved in the progressive impairment of the interdependence between cells that consist ...
T. Oshitari
semanticscholar +1 more source
Advanced Glycation End-Products and Their Effects on Gut Health
Nutrients, 2023 Dietary advanced glycation end-products (AGEs) are a heterogeneous group of compounds formed when reducing sugars are heated with proteins, amino acids, or lipids at high temperatures for a prolonged period.
Kate Phuong-Nguyen +3 more
semanticscholar +1 more source
Journal of Dental Sciences, 2023 Background/purpose: Advanced glycation end products (AGEs) are known to accumulate in the periodontal tissues of patients with diabetes mellitus (DM). Through this study, we aimed to investigate the distribution of AGEs and the receptor of AGEs (RAGE) in
Ya-Han Chang +4 more
doaj +1 more source
Advanced glycation end products [PDF]
Dermato-Endocrinology, 2012 Aging is the progressive accumulation of damage to an organism over time leading to disease and death. Aging research has been very intensive in the last years aiming at characterizing the pathophysiology of aging and finding possibilities to fight age-related diseases. Various theories of aging have been proposed.
Gkogkolou, Paraskevi, Böhm, Markus
openaire +2 more sources