Results 21 to 30 of about 81,199 (355)

Role of advanced glycation end products in cellular signaling

Redox Biology, 2014
Improvements in health care and lifestyle have led to an elevated lifespan and increased focus on age-associated diseases, such as neurodegeneration, cardiovascular disease, frailty and arteriosclerosis.
Christiane Ott, Kathleen Jacobs, Elisa Haucke, Anne Navarrete Santos, Tilman Grune, Andreas Simm   +5 more
doaj   +2 more sources

Effects of advanced glycation end products on stem cell [PDF]

Frontiers in Cell and Developmental Biology
In recent years, stem cell therapy has become a pivotal component of regenerative medicine. Stem cells, characterized by their self-renewal capacity and multidirectional differentiation potential, can be isolated from a variety of biological tissues ...
Zetai Zheng, Hui Zhou, Wenwen Zhang, Tingyu Wang, Sathiskumar Swamiappan, Xinsheng Peng, Yanfang Zhou   +6 more
doaj   +2 more sources

The effect of Galega officinalis L. extract on the content of the advanced glycation end products and their receptors in rat leukocytes under experimental diabetes mellitus

Біологічні студії, 2021
Background. Diabetes mellitus intensifies non-enzymatic glycosylation (glycation) of biomolecules under conditions of chronic hyperglycemia and facilitates accumulation of advanced glycation end products.
Kh. Ye. Furtak, H. Ya. Hachkova, N. O. Sybirna   +2 more
doaj   +1 more source

A Role for Advanced Glycation End Products in Molecular Ageing

International Journal of Molecular Sciences, 2023
Ageing is a composite process that involves numerous changes at the cellular, tissue, organ and whole-body levels. These changes result in decreased functioning of the organism and the development of certain conditions, which ultimately lead to an ...
K. Zgutka, M. Tkacz, Patrycja Tomasiak, M. Tarnowski   +3 more
semanticscholar   +1 more source

Advanced Glycation End-Products (AGEs): Formation, Chemistry, Classification, Receptors, and Diseases Related to AGEs

Cells, 2022
Advanced glycation end-products (AGEs) constitute a non-homogenous, chemically diverse group of compounds formed either exogeneously or endogeneously on the course of various pathways in the human body.
Aleksandra Twarda-Clapa, Aleksandra Olczak, A. Białkowska, M. Koziołkiewicz   +3 more
semanticscholar   +1 more source

Advanced glycation end products and cognitive impairment in schizophrenia.

PLoS ONE, 2021
Advanced glycation end products play a key role in the pathophysiology of schizophrenia. Cognitive impairment is one of the central features of schizophrenia; however, the association between advanced glycation end products and cognitive impairment ...
Akiko Kobori, Mitsuhiro Miyashita, Yasuhiro Miyano, Kazuhiro Suzuki, Kazuya Toriumi, Kazuhiro Niizato, Kenichi Oshima, Atsushi Imai, Yukihiro Nagase, Akane Yoshikawa, Yasue Horiuchi, Syudo Yamasaki, Atsushi Nishida, Satoshi Usami, Shunya Takizawa, Masanari Itokawa, Heii Arai, Makoto Arai   +17 more
doaj   +1 more source

Advanced Glycation End-Products and Diabetic Neuropathy of the Retina

International Journal of Molecular Sciences, 2023
Diabetic retinopathy is a tissue-specific neurovascular impairment of the retina in patients with both type 1 and type 2 diabetes. Several pathological factors are involved in the progressive impairment of the interdependence between cells that consist ...
T. Oshitari
semanticscholar   +1 more source

Advanced Glycation End-Products and Their Effects on Gut Health

Nutrients, 2023
Dietary advanced glycation end-products (AGEs) are a heterogeneous group of compounds formed when reducing sugars are heated with proteins, amino acids, or lipids at high temperatures for a prolonged period.
Kate Phuong-Nguyen, B. McNeill, K. Aston-Mourney, L. Rivera   +3 more
semanticscholar   +1 more source

Advanced Glycation End Products and Diabetes Mellitus: Mechanisms and Perspectives

Biomolecules, 2022
Persistent hyperglycemic state in type 2 diabetes mellitus leads to the initiation and progression of non-enzymatic glycation reaction with proteins and lipids and nucleic acids.
Mariyam Khalid, G. Petroianu, A. Adem
semanticscholar   +1 more source

Advanced glycation end products modulate electrophysiological remodeling of right ventricular outflow tract cardiomyocytes: A novel target for diabetes‐related ventricular arrhythmogenesis

Physiological Reports, 2022
Diabetes mellitus is associated with cardiovascular disease and cardiac arrhythmia. Accumulation of advanced glycation end products closely correlates with cardiovascular complications through mitochondrial dysfunction or oxidative stress and evoke ...
Yao‐Chang Chen, Yen‐Yu Lu, Wen‐Shiann Wu, Yung‐Kuo Lin, Yi‐Ann Chen, Shih‐Ann Chen, Yi‐Jen Chen   +6 more
doaj   +1 more source