Advanced Glycation End Products Acutely Impair Ca2+ Signaling in Bovine Aortic Endothelial Cells [PDF]
, 2013 Post-translational modification of proteins in diabetes, including formation of advanced glycation end products (AGEs) are believed to contribute to vascular dysfunction and disease.
Alicia J. Jenkins +5 more
core +2 more sources
Assessment of Advanced Glycation End Products and Receptors and the Risk of Dementia
JAMA Network Open, 2021 Key Points Question Are advanced glycation end products (AGEs) and their receptor (RAGE) associated with cognition and dementia? Findings In this cohort study among 3889 adults from the general Dutch population, markers of RAGE in plasma were associated ...
Jinluan Chen +7 more
semanticscholar +1 more source
Diabetes, hypertension, and cardiovascular disease: clinical insights and vascular mechanisms [PDF]
, 2018 Hypertension and type 2 diabetes are common comorbidities. Hypertension is twice as frequent in patients with diabetes compared with those who do not have diabetes.
Guzik, Tomasz J. +2 more
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The effects of advanced glycation end‐products on skin and potential anti‐glycation strategies
Experimental DermatologyThe advanced glycation end‐products (AGEs) are produced through non‐enzymatic glycation between reducing sugars and free amino groups, such as proteins, lipids or nucleic acids.
Lingyu Wang, Yanfei Jiang, Chunyue Zhao
semanticscholar +1 more source
Advanced Glycation end products (AGEs) in food: focusing on Mediterranean pasta [PDF]
, 2015 5Advanced glycation end products, also known as glycotoxins, are a diverse group of highly oxidant compounds with pathogenic significance in aged-chronic disease, including diabetes, cardiovascular disease and neurodegenerative disease. They are produced
Abate, Giulia +4 more
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Advanced Glycation End Products in Clinical Nephrology
Kidney and Blood Pressure Research, 2004 As a result of oxidative and carbonyl stress, advanced glycation end products (AGEs) are involved in the pathogenesis of severe and frequent diseases and their fatal vascular/cardiovascular complications, i.e. diabetes mellitus and its complications (nephropathy, angiopathy, neuropathy and retinopathy, renal failure and uremic and dialysis-associated ...
M, Kalousová +4 more
openaire +2 more sources
Insights into the pathogenesis of nicotine addiction. Could a salivary biosensor be useful in Nicotine Replacement Therapy (NRT)? [PDF]
, 2019 Nicotine has gained the attention of the medical community due to its insidious addictive mechanisms which lead to chronic consumption. The multitude of compounds derived from tobacco smoke have local and systemic negative impacts, resulting in a large ...
Alexescu, Teodora G +13 more
core +2 more sources
Advanced Glycation End-products and Atherosclerosis
Annals of Medicine, 1996 The late rearrangements of the covalent nonenzymatic modification of proteins by glucose, called advanced glycation end-products (AGEs), have been shown to accumulate in diabetic and ageing tissues. AGEs elicit a wide range of cell-mediated responses leading to vascular dysfunction, matrix expansion and athero- and glomerulosclerosis.
openaire +2 more sources
Cells, 2021 Systemic lupus erythematosus (SLE) is characterized by abnormal action of the immune system and a state of chronic inflammation. The disease can cause life-threatening complications.
Agnieszka Nowak +5 more
doaj +1 more source
Advanced Glycation End Products Evolution after Pancreas-Kidney Transplantation: Plasmatic and Cutaneous Assessments [PDF]
, 2016 Diabetes mellitus leads to increased Advanced Glycation End Products (AGE) production, which has been associated with secondary diabetic complications. Type 1 diabetic patients undergoing pancreas-kidney transplantation (SPKT) can restore normoglycemia ...
Castro-Henriques, A. +8 more
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