Results 1 to 10 of about 62,789 (373)

In Skeletal Muscle Advanced Glycation End Products (AGEs) Inhibit Insulin Action and Induce the Formation of Multimolecular Complexes Including the Receptor for AGEs*

Journal of Biological Chemistry, 2008
Chronic hyperglycemia promotes insulin resistance at least in part by increasing the formation of advanced glycation end products (AGEs). We have previously shown that in L6 myotubes human glycated albumin (HGA) induces insulin resistance by activating ...
A. Cassese, I. Esposito, F. Fiory, A. Barbagallo, F. Paturzo, P. Mirra, L. Ulianich, Ferdinando Giacco, Claudia Iadicicco, A. Lombardi, F. Oriente, E. van Obberghen, F. Beguinot, P. Formisano, C. Miele   +14 more
semanticscholar   +1 more source

The specific localization of advanced glycation end-products (AGEs) in rat pancreatic islets

Journal of Pharmacological Sciences, 2017
Advanced glycation end-products (AGEs) are produced by non-enzymatic glycation between protein and reducing sugar such as glucose. Although glyceraldehyde-derived AGEs (Glycer-AGEs), one of the AGEs subspecies, have been reported to be involved in the ...
Yuta Morioka, Kiyoshi Teshigawara, Yasuko Tomono, Dengli Wang, Yasuhisa Izushi, Hidenori Wake, Keyue Liu, Hideo Kohka Takahashi, Shuji Mori, Masahiro Nishibori   +9 more
doaj   +1 more source

In Vitro Kinetic Studies of Formation of Antigenic Advanced Glycation End Products (AGEs)

Journal of Biological Chemistry, 1997
Nonenzymatic protein glycation (Maillard reaction) leads to heterogeneous, toxic, and antigenic advanced glycation end products (“AGEs”) and reactive precursors that have been implicated in the pathogenesis of diabetes, Alzheimer's disease, and normal ...
Ashley Booth, R. Khalifah, P. Todd, B. Hudson   +3 more
semanticscholar   +1 more source

Isoferulic Acid, a New Anti-Glycation Agent, Inhibits Fructose- and Glucose-Mediated Protein Glycation in Vitro

Molecules, 2013
The inhibitory activity of isoferulic acid (IFA) on fructose- and glucose-mediated protein glycation and oxidation of bovine serum albumin (BSA) was investigated.
Sirichai Adisakwattana, Catherine B. Chan, Aramsri Meeprom, Weerachat Sompong   +3 more
doaj   +1 more source

Identification of Galectin-3 As a High-Affinity Binding Protein for Advanced Glycation End Products (AGE): A New Member of the AGE-Receptor Complex [PDF]

, 1995
Helen Vlassara, Yong Ming Li, Farhad Imani, Donald Wojciechowicz, Zhi Yang, Fu‐Tong Liu, Anthony Cerami   +6 more
openalex   +1 more source

Pathogenic Role of Advanced Glycation End-Products (Ages): An Overview [PDF]

, 1999
Miriam F. W.eiss
openalex   +1 more source

Food advanced glycation end products as potential endocrine disruptors: An emerging threat to contemporary and future generation

Environment International, 2019
Mankind exposure to chemicals in the past century has increased dramatically throughout environment. There is no question that chemicals interfere with the physiology of biological system.
Guna Ravichandran, Dinesh Kumar Lakshmanan, Karthik Raju, Abbirami Elangovan, Gayathri Nambirajan, Arul Ananth Devanesan, Sivasudha Thilagar   +6 more
doaj   +1 more source

The possible therapeutic role of advanced glycation end-product inhibitors in ischemic stroke

Brain Research Bulletin
The advanced glycation end-products (AGEs) are toxic molecules result from non-enzymatic interactions of sugar with lipids or proteins. AGEs promote the generation of reactive oxygen species that induce the release of pro-inflammatory cytokines, and ...
Nada H. Aljarba, Hayder M. Al-Kuraishy, Ali I. Al-Gareeb, Mustafa M. Shokr, Marios Papadakis, Athanasios Alexiou, Mubarak Alruwaili, Mohammed Alrouji, Mohammed S. Alshammari, Gaber El-Saber Batiha   +9 more
doaj   +1 more source

Advanced glycation end products (AGEs)‐induced expression of TGF‐β1 is suppressed by a protease in the tubule cell line LLC‐PK1 [PDF]

, 2001
Guangsheng Xiang, Reinhard Schinzel, Andreas Simm, Gerald Münch, Katarı́na Šebeková, Michael Kasper, Toshimitsu Niwa, Christoph Schmitz, A. Heidland   +8 more
openalex   +1 more source

Advanced glycation end-product cross-link breakersA novel approach to cardiovascular pathologies related to the aging process [PDF]

, 2004
George L. Bakris, A Bank, D KASS, J NEUTEL, Richard A. Preston, Suzanne Oparil   +5 more
openalex   +1 more source