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Παράμετροι οξειδωτικού στρες και γυναικεία γονιμότητα: Ο ρόλος των προϊόντων τελικής γλυκοζυλίωσης ( Advanced glycation end products - AGES) [PDF]

, 2022
Το οξειδωτικό στρες είναι συνέπεια της συμμετοχής του οξυγόνου στην αερόβια αναπνοή των ζωντανών οργανισμών και αποτελεί κατάσταση ανισορροπίας μεταξύ της παραγωγής ενεργών ριζών οξυγόνου (reactive oxygen species - ROS) και της ικανότητας ενδογενών ...
Κούρτη Μαριάνθη, Kourti Marianthi   +1 more
core   +1 more source

Urinary excretion of fluorescent advanced glycation end products (AGEs) in the elderly

The Journal of nutrition, health and aging, 2008
3
Maza Cave, María Pía de la, Bravo, A., Leiva Balich, Laura, Gattas, Vivien, Barrera Acevedo, María, Petermann, M., Garrido, F., Uribarri, Jaime, Hirsch Birn, Sandra, Bunout Barnett, Daniel   +9 more
openaire   +5 more sources

Enhanced expression of receptor for advanced glycation end-products is associated with low circulating soluble isoforms of the receptor in Type 2 diabetes

, 2010
The sRAGE [soluble RAGE (receptor for advanced glycation end-products)] lack the transmembrane and cytoplasmic domain of the full-length receptor and can function as a decoy for RAGE ligands.
D. John Betteridge, Lin Leng, Richard Bucala, Tam, XHL, Bucala, R, Leng, L, Betteridge, DJ, Sammy W. M. Shiu, Kathryn C. B. Tan, Tan, KCB, Xystus H. L. Tam, Shiu, SWM   +11 more
core   +1 more source

The Neutrophil‐To‐Lymphocyte Ratio as an Associated Biomarker of Diabetic Nephropathy in Type 2 Diabetes Mellitus

Journal of Clinical Laboratory Analysis, EarlyView.
Type 2 diabetes mellitus (T2DM) is associated with chronic low‐grade systemic inflammation. This study evaluated the neutrophil‐to‐lymphocyte ratio (NLR) as a practical inflammatory biomarker in T2DM. A cross‐sectional study was conducted in Hodeidah City among 82 participants: 42 T2DM patients and 40 healthy controls.
Yousef A. D. Alkhadem, Abdulmajeed A. A. Almaleki, Ali S. G. Alghamdi, Mohammed S. Al‐Ghamdi, Mohammed H. Mukhtar, Ali B. Al‐Zubaidy, Yahya Alsayaad   +6 more
wiley   +1 more source

Both Ca2+ and Zn2+ are essential for S100A12 protein oligomerization and function [PDF]

, 2009
Background Human S100A12 is a member of the S100 family of EF-hand calcium-modulated proteins that are associated with many diseases including cancer, chronic inflammation and neurological disorders.
Lednev, Igor K., Helmut Wittkowski, Anatoli Ianoul, Igor B Bronstein, Shekhtman, Alexander, Bjoerk, Per, Alexander Shekhtman, Per Bjoerk, Foell, Dirk, Wei He, Igor K Lednev, Olga V Moroz, He, Wei, Burkitt, William I., Xie, Jingjing, Derrick, Peter J., Bronstein, Igor B., Vera Novitskaya, Polyakova, Oxana, Ianoul, Anatoli, Dirk Foell, Will Burkitt, Oxana Polyakova, Moroz, Olga V., Peter J Derrick, Wittkowski, Helmut, Novitskaya, Vera, Jingjing Xie   +27 more
core   +1 more source

MicroRNA‐Mediated Autophagy and Cardiovascular Diseases: Exploring the Crossroads of Atherosclerosis and Beyond

Journal of Clinical Laboratory Analysis, EarlyView.
This graphical abstract illustrates the dynamic bidirectional crosstalk between microRNA biogenesis and autophagy, which serves as a critical regulatory axis in cardiovascular homeostasis. We highlight how specific miRNAs modulate autophagic flux to mitigate vascular inflammation and plaque instability, while concurrently, the autophagic machinery ...
Sepehr Ebrahimi‐Dehkordi, Amir Hossein Barjasteh, Aida Zarei, Sina Bazmi, Sarah Vaseghi, Sara Ashna, Amirreza Solati, Ali Yousefzadeh, Bita Safarzadeh Nasrabad, Zahra Mohammadi, Hamed Haddad Kashani, Mohammad Hossein Pourhanifeh   +11 more
wiley   +1 more source

Advanced Glycation End Products Induce Microglial Activation and Impair Neurodevelopment in Human iPSC-Derived Brain Organoids

Organoids
Advanced Glycation End Products (AGEs) are reactive compounds formed through the non-enzymatic glycation of proteins, lipids, or nucleic acids due to exposure to reducing sugars.
Rika Kumar, Grace Shinn, Jimmy Lin, Qingshun Q. Li, Yiling Hong   +4 more
doaj   +1 more source

Role of advanced glycation end products in mobility and considerations in possible dietary and nutritional intervention strategies

Nutrition & Metabolism, 2018
Advanced glycation end products (AGEs), a group of compounds that are formed by non-enzymatic reactions between carbonyl groups of reducing sugars and free amino groups of proteins, lipids or nucleic acids, can be obtained exogenously from diet or formed
Jie-Hua Chen, Xu Lin, Cuihong Bu, Xuguang Zhang   +3 more
doaj   +1 more source

Gymnema sylvestre: Bioactive constituents, health benefits, and emerging applications in nutraceuticals and functional foods

JSFA reports, EarlyView.
Abstract Gymnema sylvestre (Retz.) R.Br. ex‐Schult., commonly known as “gurmar” or “sugar destroyer,” belongs to the Apocynaceae family and is traditionally used in Ayurveda for diabetes management. This review synthesizes ethnomedicinal evidence with contemporary pharmacological studies, to evaluate the therapeutic properties and mechanistic actions ...
Faiza Saeed, Muhammad Tauseef Sultan, Hassan Raza, Ahmad Mujtaba Noman, Nimra Haroon, Entessar Mohammad Al Jbawi   +5 more
wiley   +1 more source

Molecular mechanisms linking food processing to the human gut microbiome and metabolic health: A critical review

JSFA reports, EarlyView.
Abstract Food processing can improve safety, shelf life, digestibility and sensory quality, but it can also alter the food matrix, remove microbiota‐accessible substrates and introduce additives or heat‐derived compounds that modify host–microbe interactions.
Elijah Kolawole Oladipo, Oluwatosin Tumininu Olasinde, Oluwaseyi Samuel Akinpelu, Babarinde Jesulayomi Mercy, Olakanmi Oluwakemi Deborah, Ojo Oluwalonimi Christiana, Oyeyiola Olawumi Hezekiah, Christian Chibuike Aguoru, Diovu Charles Chinedu, Anyaoha Emmanuel Obinna, Helen Onyeaka   +10 more
wiley   +1 more source