Results 21 to 30 of about 42,909 (288)

Advanced Glycation End Products and Psoriasis

Vaccines, 2023
Advanced glycation end products (AGEs) are biologically active compounds formed physiologically throughout a sequence of chemical reactions, to generate highly oxidant-reactive aldehydes that combine covalently to proteins.
Martina Maurelli, Paolo Gisondi, Giampiero Girolomoni   +2 more
doaj   +1 more source

Advanced glycation end products [PDF]

Dermato-Endocrinology, 2012
Aging is the progressive accumulation of damage to an organism over time leading to disease and death. Aging research has been very intensive in the last years aiming at characterizing the pathophysiology of aging and finding possibilities to fight age-related diseases. Various theories of aging have been proposed.
Gkogkolou, Paraskevi, Böhm, Markus
openaire   +2 more sources

Advanced glycation end products (AGEs) activate mast cells [PDF]

British Journal of Pharmacology, 2010
BACKGROUND AND PURPOSEAdvanced glycation endproducts (AGEs) represent one of the many types of chemical modifications that occur with age in long‐lived proteins. AGEs also accumulate in pathologies such as diabetes, cardiovascular diseases, neurodegeneration and cancer. Mast cells are major effectors of acute inflammatory responses that also contribute
E, Sick, S, Brehin, P, André, G, Coupin, Y, Landry, K, Takeda, J P, Gies   +6 more
openaire   +2 more sources

Advanced glycation end-products: Mechanics of aged collagen from molecule to tissue [PDF]

, 2017
Concurrent with a progressive loss of regenerative capacity, connective tissue aging is characterized by a progressive accumulation of Advanced Glycation End-products (AGEs).
Andreassen, Ansari, Avery, Bailey, Bedi, Cheng, Del Turco, Dressler, Dyer, Fessel, Fessel, Fessel, Fratzl, Gautieri, Gautieri, Gautieri, Goh, Goh, Grandhee, Gupta, Hansen, Kraft, Lavagnino, Li, Li, Meier, Monnier, Nagaraj, Nair, Reddy, Reigle, Rigoldi, Sasaki, Schnider, Sell, Sell, Sensi, Slatter, Snedeker, Sroga, Su, Su, Svensson, Svensson, Szczesny, Szczesny, Tanaka, Tang, Tang, Thorpe, Toyama, Vashishth, Verzijl, Verzijl, Vesentini, Vincent, Willett, Wu, Yamagishi, Zimmermann   +59 more
core   +2 more sources

Do advanced glycation end products contribute to food allergy?

Frontiers in Allergy, 2023
Sugars can bind non-enzymatically to proteins, nucleic acids or lipids and form compounds called Advanced Glycation End Products (AGEs). Although AGEs can form in vivo, factors in the Western diet such as high amounts of added sugars, processing methods ...
P. K. Smith, C. Venter, L. O’Mahony, R. Berni Canani, O. J. L. Lesslar   +4 more
doaj   +1 more source

A Role for Advanced Glycation End Products in Molecular Ageing

International Journal of Molecular Sciences, 2023
Ageing is a composite process that involves numerous changes at the cellular, tissue, organ and whole-body levels. These changes result in decreased functioning of the organism and the development of certain conditions, which ultimately lead to an increased risk of death.
Katarzyna Zgutka, Marta Tkacz, Patrycja Tomasiak, Maciej Tarnowski   +3 more
openaire   +2 more sources

Advanced Glycation End Products in Age-related Macular Degeneration [PDF]

Archives of Ophthalmology, 1998
To investigate the localization of N epsilon-(carboxymethyl)lysine (CML), a component and major immunologic epitope of advanced glycation end products, in aged eyes and choroidal neovascular membranes (CNVMs) surgically excised from eyes with age-related macular degeneration.Immunohistochemistry for CML was performed using 8 snap-frozen, surgically ...
T, Ishibashi, T, Murata, M, Hangai, R, Nagai, S, Horiuchi, P F, Lopez, D R, Hinton, S J, Ryan   +7 more
openaire   +2 more sources

Advanced glycation end products (AGEs) promote melanogenesis through receptor for AGEs [PDF]

Scientific Reports, 2016
AbstractAccumulation of advanced glycation end products (AGEs) is linked with development or aggravation of many degenerative processes or disorders, including aging and atherosclerosis. AGEs production in skin cells is known to promote stiffness and loss of elasticity through their buildup in connective tissue.
Eun Jung Lee, Ji Young Kim, Sang Ho Oh
openaire   +3 more sources

Oxidative stress, protein glycation and nutrition – interactions relevant to health and disease throughout the lifecycle [PDF]

, 2014
Protein glycation has been studied for over a century now and plays an important role in disease pathogenesis throughout the lifecycle. Strongly related to diabetic complications, glycation of Hb has become the gold standard method for diabetes diagnosis
American Diabetes, Antonis Vlassopoulos, Bhagwat, El-Salem, Emilie Combet, Hao, Hodge, Khaw, Koenig, Maillard, Malickova, Michael E. J. Lean, Monnier, Nicholl, Rothwell, Schmidt, Sell, Vlassara   +17 more
core   +3 more sources

RAGE Signaling in Skeletal Biology [PDF]

, 2019
PURPOSE OF REVIEW: The receptor for advanced glycation end products (RAGE) and several of its ligands have been implicated in the onset and progression of pathologies associated with aging, chronic inflammation, and cellular stress. In particular, the
Davis, Hannah M., Essex, Alyson L., Plotkin, Lilian I.   +2 more
core   +2 more sources