Advanced Glycation End Product Recognition by the Receptor for AGEs [PDF]
Structure, 2011 Nonenzymatic protein glycation results in the formation of advanced glycation end products (AGEs) that are implicated in the pathology of diabetes, chronic inflammation, Alzheimer's disease, and cancer. AGEs mediate their effects primarily through a receptor-dependent pathway in which AGEs bind to a specific cell surface associated receptor, the ...
Xue, Jing +9 more
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How Can Diet Affect the Accumulation of Advanced Glycation End-Products in the Human Body?
Foods, 2016 The accumulation of advanced glycation end products (AGEs) is associated with the complications of diabetes, kidney disease, metabolic disorders and degenerative diseases. It is recognized that the pool of glycation products found in the human body comes
Axel Guilbaud +3 more
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A new gender-specific model for skin autofluorescence risk stratification [PDF]
, 2015 Advanced glycation endproducts (AGEs) are believed to play a significant role in the pathophysiology of a variety of diseases including diabetes and cardiovascular diseases.
Ahmad, MS +4 more
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Role of galectin-3 in bone cell differentiation, bone pathophysiology and vascular osteogenesis [PDF]
, 2017 Galectin-3 is expressed in various tissues, including the bone, where it is considered a marker of chondrogenic and osteogenic cell lineages. Galectin-3 protein was found to be increased in the differentiated chondrocytes of the metaphyseal plate ...
Fantauzzi, Claudia Blasetti +3 more
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Cells, 2019 Advanced glycation end products (AGEs) are the end products of the glycation reaction and have a great importance in clinical science for their association with oxidative stress and inflammation, which play a major role in most chronic diseases, such as ...
Margherita Borriello +2 more
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Advanced glycation end product level, diabetes, and accelerated cognitive aging [PDF]
Neurology, 2011 Several studies report that diabetes increases risk of cognitive impairment; some have hypothesized that advanced glycation end products (AGEs) underlie this association. AGEs are cross-linked products that result from reactions between glucose and proteins.
Kristine, Yaffe +10 more
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Insights into the pathogenesis of nicotine addiction. Could a salivary biosensor be useful in Nicotine Replacement Therapy (NRT)? [PDF]
, 2019 Nicotine has gained the attention of the medical community due to its insidious addictive mechanisms which lead to chronic consumption. The multitude of compounds derived from tobacco smoke have local and systemic negative impacts, resulting in a large ...
Alexescu, Teodora G +13 more
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Inhibitory Effect of Tectoridin on the Formation of Advanced Glycation End Products
Shipin gongye ke-jiIt is of great significance to search for advanced glycation end products (AGEs) inhibitors with high activity and low side effects from food-borne natural products for the prevention and improvement of related diseases.
Fangyu GUO +6 more
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Біологічні студії, 2021 Background. Diabetes mellitus intensifies non-enzymatic glycosylation (glycation) of biomolecules under conditions of chronic hyperglycemia and facilitates accumulation of advanced glycation end products.
Kh. Ye. Furtak +2 more
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Assessment of Oral Glycine and Lysine Therapy on Receptor for Advanced Glycation End Products and Transforming Growth Factor Beta Expression in the Kidney of Streptozotocin-Induced Diabetic Rats in Comparison with Normal Rats [PDF]
Journal of Kerman University of Medical Sciences, 2014 Background & Aims: Today, diabetic nephropathy is considered to be one of the most common causes of end stage renal disease. Uncontrolled hyperglycemia, and consequently, production of advanced glycation end products activate pathways which play key ...
Somayeh Sadat Heidary +3 more
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