Results 71 to 80 of about 8,796,374 (289)

Gut Microbiota‐Derived Indole‐3‐Propionic Acid Alleviates Diabetic Osteoporosis Through Nrf2‐Mediated Ferroptosis Suppression

Advanced Science, EarlyView.
Diabetes‐associated dysbiosis is accompanied by reduced Clostridium abundance, impaired microbial tryptophan metabolism, and lower circulating indole‐3‐propionic acid (IPA). Exogenous IPA improves trabecular microarchitecture and bone formation and restores Nrf2‐associated antioxidant signaling in bone marrow mesenchymal stem cells, limiting iron ...
Jinwu Bai, Qinyong You, Gao Si, Daole Hu, Ao Sun, Shilong Su, Ruideng Wang, Jixing Fan, Shan Gao, Tengjiao Zhu, Chun‐Li Song, Fang Zhou, Yang Lv   +12 more
wiley   +1 more source

Fluorescent serum and urinary advanced glycoxidation end-products in non- diabetic subjects

Biological Research, 2007
Introduction: Advanced glycoxidation end-products (AGEs) are involved in age-related conditions and diabetic complications. Diet intake contributes to their circulating concentrations. Aim: To measure serum and urinary AGEs in non-diabetic volunteers and
MP DE LA MAZA, A BRAVO, L LEIVA, V GATTÁS, M PETERMANN, F GARRIDO, D BUNOUT, S HIRSCH, G BARRERA, M FERNÁNDEZ   +9 more
doaj  

Role of polyphenols in modulating AGEs-RAGE axis in cancer, a review

Bulletin of the National Research Centre
Background and purpose The glycation process produces a great deal of free radicals during its initial and propagation phases. It also produces carbonyl species and reactive dicarbonyl species, the most reactive of which is methylglyoxal (MG), which may ...
Ritu Raina, P. S. K. Sanjana, Saleha Mohammed Razaulla, Ravinder Bhatt, Arif Hussain   +4 more
doaj   +1 more source

Targeting the AGEs-RAGE axis: pathogenic mechanisms and therapeutic interventions in diabetic wound healing

Frontiers in Medicine
Diabetes is a global health problem, with diabetic wounds constituting one of its most severe complications. Advanced glycation end products (AGEs) and their receptor, the receptor for advanced glycation end products (RAGE), play a key role in the ...
Haohui Lin, Yi Yang, Xia Wang, Manhon Chung, Li Zhang, Sa Cai, Xiaohua Pan, Yu Pan   +7 more
doaj   +1 more source

Dietary Maillard reaction products: implications for human health and disease [PDF]

, 2009
When foods are heat processed, the sugars and lipids react with the proteins they contain via the Maillard and related reactions to form a wide range of products.
J. M. AMES, Ames, Jenny
core   +1 more source

Biomimetic Scaffold‐Based 3D Models for Decoding Cancer Biology and Advancing Therapy

Advanced Science, EarlyView.
A timeline of the research history of 3D biomimetic scaffold materials and platforms. With advances in biomimetic materials and 3D scaffold technologies, their functional scope has expanded from mimicking basic physical and biochemical properties to increasingly replicating complex pathophysiological processes.
Haitao Zhao, Yuechen Han, Jie Li, Peng Luo, Lin Qi, Zhiwei Xia, Xiaosong Li, Quan Cheng, Chenshen Huang, Wantao Wu, Hao Zhang   +10 more
wiley   +1 more source

Dietary Phenolics as Reactive Carbonyl Scavengers: Potential Impact on Human Health and Mechanism of Action

Journal of Traditional and Complementary Medicine, 2013
Previous studies have demonstrated that accumulation of reactive carbonyl compounds in human tissue will accelerate the vascular damage in both diabetes and uremia. Moreover, advanced glycation progressively and irreversibly modify the proteins over time
Chi-Tang Ho, Mingfu Wang
doaj   +1 more source

The liver‐brain axis: A multidimensional regulatory network implicated in Alzheimer's disease pathogenesis and clinical implications

Animal Models and Experimental Medicine, EarlyView.
Schematic diagram of the core pathways of the liver‐brain axis in regulating AD. The liver regulates cerebral Aβ deposition, tau phosphorylation, and neuroinflammation through pathways such as metabolic detoxification (urea cycle, ketone body metabolism, glutathione antioxidant system), molecular secretion (APOE, CRP, FGF21, IGF‐1), and Aβ clearance ...
Ning Zhang, Wei Chen, Meng Wang
wiley   +1 more source

Systemic lupus erythematosus and glycation proces

Central European Journal of Immunology, 2020
Systemic lupus erythematosus (SLE) is a disease of unclear causes, which leads to major immunological disorders. It is characterized by an abnormal immune system activity resulting in the production of autoantibodies.
Agnieszka Nowak, Brygida Przywara-Chowaniec, Krystyna Tyrpień-Golder, Ewa Nowalany-Kozielska   +3 more
doaj   +1 more source

Advanced glycation end-products in liver diseases: Meta analysis

, 2021
A meta-analysis examining serum levels of advanced glycation end-products in non-alcoholic fatty-liver disease (NAFLD) and alcoholic liver disease (ALD).
Kamil Litwinowicz
core   +1 more source