Results 101 to 110 of about 339,203 (181)

Emergent behaviour and phase transitions in spatially distributed multi-cellular metabolic networks [PDF]

open access: yesarXiv
Overflow metabolism is a ubiquitous phenomenon whereby cells in aerobic conditions excrete byproducts of glycolysis, such as lactate or acetate, into the medium in a seemingly wasteful and polluting fashion. Whilst overflow may confer microbes a fitness advantage by allowing them to overcome a finite oxidative capacity, its occurrence in higher ...
arxiv  

Reply to Saint-Antonin: Low-oxygen-tolerant animals predate oceanic anoxic events [PDF]

open access: yesarXiv, 2015
It is has been assumed for over half a century that the earliest animals were obligate aerobes with relatively high oxygen requirements. However, the conserved biochemistry and widespread phylogenetic distribution of anaerobic energy metabolism in animals suggests a deep ancestral possession of the genes and enzymes necessary for a facultative ...
arxiv  

Sirt3 regulated apoptosis and aerobic glycolysis during renal interstitial fibrosis

open access: yesLinchuang shenzangbing zazhi
Objective To observe the expression of silent information regulator 3 (Sirt3), detect the level of aerobic glycolysis in renal fibrosis model and explore the role of Sirt3 in renal interstitial fibrosis.
Yong-hong Jian   +6 more
doaj   +1 more source

National Bias of International Gymnastics Judges during the 2013-2016 Olympic Cycle [PDF]

open access: yesarXiv, 2018
National bias in sports judging is a well-known issue and has been observed in several sports: judges, in the aggregate, give higher marks to athletes of the same nationality. In this work, we study the national bias of international gymnastics judges during the 2013-2016 Olympic cycle.
arxiv  

Interferon Gamma Induces Reversible Metabolic Reprogramming of M1 Macrophages to Sustain Cell Viability and Pro-Inflammatory Activity

open access: yesEBioMedicine, 2018
Classical activation of M1 macrophages with lipopolysaccharide (LPS) is associated with a metabolic switch from oxidative phosphorylation to glycolysis.
Feilong Wang   +8 more
doaj  

P53 Orchestrates Cancer Metabolism: Unveiling Strategies to Reverse the Warburg Effect [PDF]

open access: yesarXiv
Cancer cells exhibit significant alterations in their metabolism, characterised by a reduction in oxidative phosphorylation (OXPHOS) and an increased reliance on glycolysis, even in the presence of oxygen. This metabolic shift, known as the Warburg effect, is pivotal in fuelling cancer's uncontrolled growth, invasion, and therapeutic resistance.
arxiv  

Petri nets in modelling glucose regulating processes in the liver [PDF]

open access: yesarXiv
Diabetes is a chronic condition, considered one of the civilization diseases, that is characterized by sustained high blood sugar levels. There is no doubt that more and more people is going to suffer from diabetes, hence it is crucial to understand better its biological foundations.
arxiv  

LncRNA MAFG-AS1 Accelerates Cell Migration, Invasion and Aerobic Glycolysis of Esophageal Squamous Cell Carcinoma Cells via miR-765/PDX1 Axis

open access: yesCancer Management and Research, 2020
Cui-juan Qian1 ,* Zhu-rong Xu1 ,* Lu-yan Chen,1 Yi-chao Wang,2 Jun Yao1 1Institute of Tumor, School of Medicine, Taizhou University, Taizhou, Zhejiang 318000, People’s Republic of China; 2Department of Medical Laboratory, Taizhou Central Hospital ...
Qian C, Xu Z, Chen L, Wang Y, Yao J
doaj  

R-2-hydroxyglutarate attenuates aerobic glycolysis in leukemia by targeting the FTO/m6A/PFKP/LDHB axis.

open access: yesMolecules and Cells, 2021
Y. Qing   +28 more
semanticscholar   +1 more source

Loss of Abhd5 Promotes Colorectal Tumor Development and Progression by Inducing Aerobic Glycolysis and Epithelial-Mesenchymal Transition

open access: yesCell Reports, 2014
Summary: How cancer cells shift metabolism to aerobic glycolysis is largely unknown. Here, we show that deficiency of α/β-hydrolase domain-containing 5 (Abhd5), an intracellular lipolytic activator that is also known as comparative gene identification 58
Juanjuan Ou   +11 more
doaj  

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