Results 201 to 210 of about 224,058 (247)
Retinal aerobic glycolysis revisited.
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AEROBIC GLYCOLYSIS OF X-IRRADIATED THYMOCYTES
The aerobic lactate production of rat thymocyte suspensions incubated at 37 °C for 2 hours was doubled following exposure to approximately 70 r X-radiation. Lower doses down to 18 r also produced a significant increase in aerobic lactate production. Increased lactate accumulation following exposure to 1000 r was observed after incubation for as little ...
K, ARAKI, D K, MYERS
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Increased demand for NAD+ relative to ATP drives aerobic glycolysis [PDF]
Aerobic glycolysis, or preferential fermentation of glucose-derived pyruvate to lactate despite available oxygen, is associated with proliferation across many organisms and conditions.
Raphaël Ferreira +2 more
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Inhibiting aerobic glycolysis suppresses renal interstitial fibroblast activation and renal fibrosis
Chronic kidney diseases generally lead to renal fibrosis. Despite great progress having been made in identifying molecular mediators of fibrosis, the mechanism that governs renal fibrosis remains unclear, and so far no effective therapeutic antifibrosis
Yang Zhou, Junwei Yang, Qi Yuan
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Aerobic Inhibition of Glycolysis
Nature, 1958DURING investigations on the synthesis of sucrose from glucose-1-phosphate and fructose by pea seed extracts it was observed that a glycolytic system was operating in the enzymic digests1,2. The pea extract had been partially purified by precipitation with ammonium sulphate (80 per cent saturation) and dialysis against phosphate buffer at pH. 7.0.
J F, TURNER, L W, MAPSON
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Ubiquitination regulation of aerobic glycolysis in cancer
Life Sciences, 2022Aerobic glycolysis, or the Warburg effect, is regarded as a critical part of metabolic reprogramming and plays a crucial role in the occurrence and development of tumours. Ubiquitination and deubiquitination, essential post-translational modifications, have attracted increasing attention with regards to the regulation of metabolic reprogramming in ...
Yao, Xie +5 more
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Control of aerobic glycolysis in the brain in vitro
Neurochemical Research, 1980Protoveratrine-(5 microM) stimulated aerobic glycolysis of incubated rat brain cortex slices that accompanies the enhanced neuronal influx of Na+ is blocked by tetrodotoxin (3 microM) and the local anesthetics, cocaine (0.1 mM) and lidocaine (0.5 mM).
A M, Benjamin, Z H, Verjee
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Aerobic glycolysis during lymphocyte proliferation
Nature, 1976GLYCOLYSIS, for most mammalian cells, is only a prelude to the complete respiratory oxidation of glucose. Lactate production is usually barely, if at all, detectable in aerobic conditions1. Consequently, when Warburg2,3 observed that various tumours showed active aerobic glycolysis, he postulated that defective tumour cell respiration was the reason ...
Wang, T, Marquardt, C, Foker, J
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Aerobic glycolysis in the ox cornea
Experimental Eye Research, 1969Measurements of lactate production at steady state in aerobic conditions show conclusively that aerobie glycolysis does take place in the intact corneal epithelium of the ox. An earlier report to the contrary ( de Roetth, 1951 ) is resolved when the original data are reevaluated.
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Emerging roles of aerobic glycolysis in breast cancer
Clinical and Translational Oncology, 2019Altered aerobic glycolysis is a well-recognized characteristic of cancer cell energy metabolism, known as the Warburg effect. Even in the presence of abundant oxygen, a majority of tumor cells produce substantial amounts of energy through a high glycolytic metabolism, and breast cancer (BC) is no exception.
Z. Wu, J. Wu, Q. Zhao, S. Fu, J. Jin
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