Results 61 to 70 of about 339,203 (181)
Aerobic glycolysis: beyond proliferation.
Frontiers in Immunology, 2015 Aerobic glycolysis has been generally associated with cancer cell proliferation, but fascinating and novel data show that it is also coupled to a series of further cellular functions. In this Mini Review we will discuss some recent findings to illustrate
William eJones, Katiuscia eBianchi
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Glycolysis in Chronic Liver Diseases: Mechanistic Insights and Therapeutic Opportunities
Cells, 2023 Chronic liver diseases (CLDs) cover a spectrum of liver diseases, ranging from nonalcoholic fatty liver disease to liver cancer, representing a growing epidemic worldwide with high unmet medical needs.
Hengdong Qu +5 more
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Cancer Science, 2021 Improving the chemotherapy resistance of temozolomide (TMZ) is of great significance in the treatment of glioblastoma multiforme (GBM). Long non‐coding RNA just proximal to the X‐inactive specific transcript (JPX) has been proven to be involved in cancer
X. Li +5 more
semanticscholar +1 more source
Cell & Bioscience, 2023 Purpose The oncoprotein KAI1 C-terminal interacting tetraspanin (KITENIN; vang-like 1) promotes cell metastasis, invasion, and angiogenesis, resulting in shorter survival times in cancer patients. Here, we aimed to determine the effects of KITENIN on the
Mücahit Varlı +6 more
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Journal of Bone and Mineral Research, 2021 Lgr4, a G‐protein‐coupled receptor, is associated with various physiological and pathological processes including oncogenesis, energy metabolism, and bone remodeling. However, whether Lgr4 is involved in osteoblasts' metabolism is not clear.
Yu-ying Yang +8 more
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Cell Death and Disease, 2020 Metabolic switch from oxidative phosphorylation to aerobic glycolysis, which is also called the Warburg effect, is a hallmark of osteosarcoma (OS) and leads to the enhancement of cell chemoresistance, growth, metastasis, and invasion.
Yifei Shen +6 more
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Constant Growth Rate Can Be Supported by Decreasing Energy Flux and Increasing Aerobic Glycolysis
Cell Reports, 2014 Fermenting glucose in the presence of enough oxygen to support respiration, known as aerobic glycolysis, is believed to maximize growth rate. We observed increasing aerobic glycolysis during exponential growth, suggesting additional physiological roles ...
Nikolai Slavov +4 more
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eLife, 2017 Rapidly proliferating cells switch from oxidative phosphorylation to aerobic glycolysis plus glutaminolysis, markedly increasing glucose and glutamine catabolism.
Lindsey Araujo +4 more
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PKM2 coordinates glycolysis with mitochondrial fusion and oxidative phosphorylation
Protein & Cell, 2019 A change in the metabolic flux of glucose from mitochondrial oxidative phosphorylation (OXPHOS) to aerobic glycolysis is regarded as one hallmark of cancer. However, the mechanisms underlying the metabolic switch between aerobic glycolysis and OXPHOS are
Tong Li +5 more
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Molecular Medicine, 2021 Background Reprogrammed glucose metabolism of enhanced Warburg effect (or aerobic glycolysis) is considered as a hallmark of cancer. Long non-coding RNAs (lncRNAs) have been certified to play a crucial role in tumor progression. The current study aims to
Peng Deng +6 more
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