Results 61 to 70 of about 356,678 (297)
Theranostics, 2022 Background: Mechanical ventilation (MV) can induce pulmonary fibrosis. This study aims to investigate whether MV-induced pulmonary fibrosis is associated with aerobic glycolysis and seeks to uncover the underlying mechanisms mediated by integrin β3 ...
Shuya Mei +8 more
semanticscholar +1 more source
FAM129B activates Ras and promotes aerobic glycolysis [PDF]
Cell Cycle, 2016 Normal differentiated cells under normoxic conditions rely primarily on mitochondrial oxidative phosphorylation to generate the energy needed for cellular processes by oxidizing glucose-derived pyr...
Jong-Ho, Lee, Haitao, Ji, Zhimin, Lu
openaire +2 more sources
Role of aerobic glycolysis in genetically engineered mouse models of cancer
BMC Biology, 2013 The propensity of cancer cells to convert high levels of glucose to lactate through aerobic glycolysis has been intensively studied in vitro, and is now understood to be a metabolic adaptation that shunts glucose carbons toward building blocks for the ...
Dang Chi V
doaj +1 more source
Research Progress of Warburg Effect in Hepatocellular Carcinoma
Frontiers in Bioscience-LandmarkThe Warburg effect, also called aerobic glycolysis, refers to tumor cells that metabolize glucose through glycolysis even in the presence of oxygen. This rapid breakdown of glucose fuels the fast development, growth, and migration of tumor cells. Lactate,
Yanguang Yang +8 more
doaj +1 more source
Cancer Science, 2021 Improving the chemotherapy resistance of temozolomide (TMZ) is of great significance in the treatment of glioblastoma multiforme (GBM). Long non‐coding RNA just proximal to the X‐inactive specific transcript (JPX) has been proven to be involved in cancer
X. Li +5 more
semanticscholar +1 more source
Aerobic glycolysis tunes
The EMBO Journal, 2015 Increased glucose metabolism and reprogramming toward aerobic glycolysis are a hallmark of cancer cells, meeting their metabolic needs for sustained cell proliferation. Metabolic reprogramming is usually considered as a downstream consequence of tumor development and oncogene activation; growing evidence indicates, however, that metabolism on its turn ...
E. Enzo +11 more
openaire +4 more sources
Journal of Immunology Research, 2021 Mitochondrial Pyruvate Carrier 1 (MPC1), one of the rate-limiting proteins involved in glycolysis metabolism, has been demonstrated as a tumor inhibitor in several cancers.
Manzila Kuerbanjiang +6 more
doaj +1 more source
The roles of glycolysis in osteosarcoma
Frontiers in Pharmacology, 2022 Metabolic reprogramming is of great significance in the progression of various cancers and is critical for cancer progression, diagnosis, and treatment.
Zuxi Feng, Yanghuan Ou, Liang Hao
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Journal of Bone and Mineral Research, 2021 Lgr4, a G‐protein‐coupled receptor, is associated with various physiological and pathological processes including oncogenesis, energy metabolism, and bone remodeling. However, whether Lgr4 is involved in osteoblasts' metabolism is not clear.
Yu-ying Yang +8 more
semanticscholar +1 more source
FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source