Results 101 to 110 of about 29,689 (270)

Lixisenatide attenuates advanced glycation end products (AGEs)-induced degradation of extracellular matrix in human primary chondrocytes

Artificial Cells, Nanomedicine, and Biotechnology, 2019
Osteoarthritis (OA) poses a growing threat to the health of the global population. Accumulation of advanced glycation end-products (AGEs) has been shown to upregulate expression of degradative enzymes such as matrix metalloproteinases (MMPs) and a ...
Xin Li, Fangteng Jia, Zhengqing Zhu, Lanfeng Huang   +3 more
doaj   +1 more source

The relationship between the aggrecan VNTR polymorphism and its content in lumbar intervertebral discs

, 2022
P. Pękala, D. Felkle, K. Dykas, A. Jarosz, P. Elnazir, T. Konopka, J. A. Walocha, J. Dulinska-Litewka   +7 more
openalex   +1 more source

Thirty Years of Autologous Platelet Concentrates: From Platelet‐Rich Plasma to Platelet‐Rich Fibrin

Journal of Periodontal Research, EarlyView.
This review highlights the 30 years of evolution of APCs, with a focus on their clinical applications and recent technological advancements. ABSTRACT Nearly three decades have now passed since autologous platelet concentrates (APCs) were introduced into clinical practice.
Richard J. Miron, Nathan E. Estrin, Paras Ahmad, Nima Farshidfar, Masako Fujioka‐Kobayashi, Yufeng Zhang, Mario Romandini, Reinhard Gruber   +7 more
wiley   +1 more source

Genotype and phenotype in patients with ACAN gene variants: Three cases and literature review

Molecular Genetics & Genomic Medicine
Objective To characterize the phenotype spectrum, diagnosis, and response to growth‐promoting therapy in patients with ACAN variants causing familial short stature. Methods Three families with ACAN variants causing short stature were reported.
Wei Tang, Ke‐Mi Wu, Qiong Zhou, Yan‐Fei Tang, Jun‐Fen Fu, Guan‐Ping Dong, Chao‐Chun Zou   +6 more
doaj   +1 more source

BMP-2 shows characteristic extracellular patterns in osteoarthritic cartilage: a preliminary report

GMS Interdisciplinary Plastic and Reconstructive Surgery DGPW, 2013
To determine bone morphogenetic protein (BMP)-2 protein and Aggrecan in osteoarthritic and healthy cartilage with special regard to localization and degree of cartilage damage 95 samples representing osteoarthritic cartilage and 17 samples out of normal ...
Pester, Julia K., Stumpfe, Stephanie, Steinert, Susanne, Marintschev, Ivan, Aurich, Matthias, Hofmann, Gunther O.   +5 more
doaj   +1 more source

Effects of Proteinase Inhibitors on Aggrecan Catabolism in Chondrocyte Cultures^a [PDF]

, 1994
Carl R. Flannery, John D. Sandy
openalex   +1 more source

Genetic and Molecular Determinants of Familial Transmission of Skeletal Malocclusions

Orthodontics &Craniofacial Research, EarlyView.
ABSTRACT Families studies conducted in different ethnic populations worldwide have helped elucidate the molecular and genetic factors involved in the development of skeletal class III malocclusion. Therefore, the aim of this study is to provide an updated summary.
Alexandra Dehesa‐Santos, Lucia Carreño‐Gomez, Rosa Yañez‐Vico, Alejandro Iglesias‐Linares   +3 more
wiley   +1 more source

Comparison of the effects of triamcinolone acetonide or platelet-rich plasma on expression of extracellular matrix-related genes in equine healthy chondrocytes in vitro

Ciência Rural
: In healthy cartilage, chondrocytes maintain an expression of collagens and proteoglycans and are sensitive to growth factors and cytokines that either enhance or reduce type II collagen synthesis. In osteoarthritis, pro-inflammatory cytokines, such as
Heloisa Einloft Palma, Miguel Gallio, Gabriele Biavaschi da Silva, Camila Cantarelli, Kalyne Bertolin, Patrícia Wolkmer, Julien Wergutz, Luciana Maria Fontanari Krause, Alexandre Krause, Alfredo Quites Antoniazzi, Karin Erica Brass, Flavio Desessards De La Corte   +11 more
doaj   +1 more source

Advantages of horizontal centrifugation of platelet‐rich fibrin in regenerative medicine and dentistry

Periodontology 2000, EarlyView.
Abstract The aim of this comprehensive review was to evaluate comparative studies on horizontal and fixed‐angle centrifugation methods for preparing platelet‐rich fibrin (PRF). Furthermore, additional studies utilizing horizontal PRF (H‐PRF) were systematically investigated.
Nima Farshidfar, Karol Alí Apaza Alccayhuaman, Nathan E. Estrin, Paras Ahmad, Anton Sculean, Yufeng Zhang, Richard J. Miron   +6 more
wiley   +1 more source

Mature bovine articular cartilage contains abundant aggrecan that is C-terminally truncated at Ala719-Ala720, a site which is readily cleaved by m-calpain [PDF]

, 2004
Hidefumi Oshita, John D. Sandy, Kiichi Suzuki, Atsushi Akaike, Yun Bai, Tomohiro Sasaki, Katsuji Shimizu   +6 more
openalex   +1 more source