Results 81 to 90 of about 21,330 (209)

Soluble Epoxide Hydrolase Inhibition Regulates Septoclast Activity to Promote Long Bone Growth and Fracture Healing by Enhancing Endothelial‐to‐Mesenchymal Notch Signalling

Cell Proliferation, EarlyView.
The sEH inhibitor TPPU upregulates endothelial HIF‐1α, activating the NOTCH signalling pathway between endothelial cells and mesenchymal stem cells. This promotes the differentiation and formation of FABP5+ septoclasts, enhances their participation in endochondral ossification, and ultimately improves longitudinal bone growth and fracture healing ...
Weixian Chen, Liangliang Liu, Xumeng Wang, Juanjuan Li, Jingyi Zhang, Xiaoli Shi, Qing Sun, Xu Chang, Jing Zhang, Jie Zhao, Fu Wang   +10 more
wiley   +1 more source

Comparison of the effects of triamcinolone acetonide or platelet-rich plasma on expression of extracellular matrix-related genes in equine healthy chondrocytes in vitro

Ciência Rural
: In healthy cartilage, chondrocytes maintain an expression of collagens and proteoglycans and are sensitive to growth factors and cytokines that either enhance or reduce type II collagen synthesis. In osteoarthritis, pro-inflammatory cytokines, such as
Heloisa Einloft Palma, Miguel Gallio, Gabriele Biavaschi da Silva, Camila Cantarelli, Kalyne Bertolin, Patrícia Wolkmer, Julien Wergutz, Luciana Maria Fontanari Krause, Alexandre Krause, Alfredo Quites Antoniazzi, Karin Erica Brass, Flavio Desessards De La Corte   +11 more
doaj   +1 more source

Thirty Years of Autologous Platelet Concentrates: From Platelet‐Rich Plasma to Platelet‐Rich Fibrin

Journal of Periodontal Research, EarlyView.
This review highlights the 30 years of evolution of APCs, with a focus on their clinical applications and recent technological advancements. ABSTRACT Nearly three decades have now passed since autologous platelet concentrates (APCs) were introduced into clinical practice.
Richard J. Miron, Nathan E. Estrin, Paras Ahmad, Nima Farshidfar, Masako Fujioka‐Kobayashi, Yufeng Zhang, Mario Romandini, Reinhard Gruber   +7 more
wiley   +1 more source

BMP-2 shows characteristic extracellular patterns in osteoarthritic cartilage: a preliminary report

GMS Interdisciplinary Plastic and Reconstructive Surgery DGPW, 2013
To determine bone morphogenetic protein (BMP)-2 protein and Aggrecan in osteoarthritic and healthy cartilage with special regard to localization and degree of cartilage damage 95 samples representing osteoarthritic cartilage and 17 samples out of normal ...
Pester, Julia K., Stumpfe, Stephanie, Steinert, Susanne, Marintschev, Ivan, Aurich, Matthias, Hofmann, Gunther O.   +5 more
doaj   +1 more source

The Effects of Dietary Loading on Chondrocytes Transdifferentiation During Postnatal Maxillary Growth

Orthodontics &Craniofacial Research, EarlyView.
ABSTRACT Background The mid‐palatal suture is a key growth site for transverse maxillary expansion, yet the cellular mechanisms governing its postnatal development and response to mechanical loading remain poorly defined. This study investigated the contribution of chondrocyte‐derived osteogenesis to maxillary bone formation and the influence of ...
Michael Stark, Paria Dehghanian, Ying Liu, LouisBruno Ruest, Matthew J. Kesterke, Yan Jing   +5 more
wiley   +1 more source

Oral Mucositis in Oncopediatric Patients: MTX and MMP‐1, MMP‐8, MMP‐13 Gene Polymorphisms

Oral Diseases, EarlyView.
ABSTRACT Background This study investigates the association between single‐nucleotide polymorphisms (SNPs) in the MMP‐1, MMP‐8, and MMP‐13 genes and the risk of oral mucositis development in paediatric patients with leukaemia and lymphoma who are undergoing methotrexate (MTX) treatment.
Nicole Januário Ribeiro, Larissa Helena Tissi, Mateus Tissot Escobar, Ana Maria Gondim Valença, Ricardo Lehtonen Rodrigues Souza, Naila Francis Paulo de Oliveira, Maria Cristina Leme Godoy Santos   +6 more
wiley   +1 more source

The structure and function of cartilage proteoglycans [PDF]

European Cells & Materials, 2006
Cartilage contains a variety of proteoglycans that are essential for its normal function. These include aggrecan, decorin, biglycan, fibromodulin and lumican. Each proteoglycan serves several functions that are determined by both its core protein and its
P J Roughley
doaj  

Advantages of horizontal centrifugation of platelet‐rich fibrin in regenerative medicine and dentistry

Periodontology 2000, EarlyView.
Abstract The aim of this comprehensive review was to evaluate comparative studies on horizontal and fixed‐angle centrifugation methods for preparing platelet‐rich fibrin (PRF). Furthermore, additional studies utilizing horizontal PRF (H‐PRF) were systematically investigated.
Nima Farshidfar, Karol Alí Apaza Alccayhuaman, Nathan E. Estrin, Paras Ahmad, Anton Sculean, Yufeng Zhang, Richard J. Miron   +6 more
wiley   +1 more source

Platelet‐rich plasma (PRP) versus injectable platelet‐rich fibrin (i‐PRF): A systematic review across all fields of medicine

Periodontology 2000, EarlyView.
Abstract This systematic review aimed to evaluate all available evidence across all fields of medicine regarding the comparative effectiveness of platelet‐rich plasma (PRP) versus injectable platelet‐rich fibrin (i‐PRF). A comprehensive search was conducted in PubMed, Scopus, and Web of Science up to September 30, 2024.
Nima Farshidfar, Mohammad Amin Amiri, Nathan E. Estrin, Paras Ahmad, Anton Sculean, Yufeng Zhang, Richard J. Miron   +6 more
wiley   +1 more source

Understanding exosomes in regenerative dentistry

Periodontology 2000, EarlyView.
Abstract Background Regenerative dentistry is shifting from cell‐based strategies to cell‐free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication.
Paras Ahmad, Anton Sculean, Richard J. Miron   +2 more
wiley   +1 more source