Results 111 to 120 of about 29,689 (270)
Aggrecan: A target molecule of autoimmune reactions
Pathology & Oncology Research, 1996 Aggrecan in cartilage forms aggregates with hyaluronan and link protein, embedded in a collagen network. It accounts for the compressive stiffness and resilience of the hyaline cartilage. Many forms of inflammatory arthritis were shown to be accompanied with aggrecan degradation and loss from the cartilage. The loss of this major component of cartilage
Edit I, Buzás +2 more
openaire +2 more sources
Periodontology 2000, EarlyView.Abstract This systematic review aimed to evaluate all available evidence across all fields of medicine regarding the comparative effectiveness of platelet‐rich plasma (PRP) versus injectable platelet‐rich fibrin (i‐PRF). A comprehensive search was conducted in PubMed, Scopus, and Web of Science up to September 30, 2024.
Nima Farshidfar +6 more
wiley +1 more source
Patients with rheumatoid arthritis have an altered circulatory aggrecan profile
BMC Musculoskeletal Disorders, 2008 Background Rheumatoid arthritis (RA) is a chronic auto-immune disease with extensive articular cartilage destruction. Aggrecan depletion, mediated by aggrecanases is one of the first signs of early cartilage erosion.
Mueller Andreas +10 more
doaj +1 more source
Internalization of Aggrecan G1 Domain Neoepitope ITEGE in Chondrocytes Requires CD44 [PDF]
, 2010 Wataru Ariyoshi +4 more
openalex +1 more source
BioMed Research International, 2014 The chondroitin sulfate proteoglycans (CSPGs) aggrecan, versican, and brevican are large aggregating extracellular matrix molecules that inhibit axonal growth of the mature central nervous system (CNS).
K. Demircan +13 more
semanticscholar +1 more source
Experimental Physiology, EarlyView.Abstract Knee osteoarthritis is experienced by hundreds of millions of people worldwide and is a major cause of disability. Although enhancing physical activity levels and the participation in exercise programmes has been proved to improve the debilitating illness of osteoarthritis, many do not engage in recommended levels of physical activity.
Karl Morgan +3 more
wiley +1 more source
The structure and function of cartilage proteoglycans [PDF]
European Cells & Materials, 2006 Cartilage contains a variety of proteoglycans that are essential for its normal function. These include aggrecan, decorin, biglycan, fibromodulin and lumican. Each proteoglycan serves several functions that are determined by both its core protein and its
P J Roughley
doaj
Elevated aggrecan mRNA in early murine osteoarthritis
Osteoarthritis and Cartilage, 1997 Male STR/ort mice develop osteoarthritis in the tibial articular cartilage. Low grade histological lesions first appear between 10-20 weeks of age. A previous study showed that the level of aggrecan, the major cartilage proteoglycan, is approximately twofold greater in the tibial cartilage of 16-19-week-old STR/ort mice compared with that in normal ...
Gaffen, John D. +2 more
openaire +2 more sources
JOR SPINE, Volume 9, Issue 1, March 2026.Methodological overview of primary bovine NP and AF cell culture. Pro‐ and anti‐inflammatory gene and protein expression analyses were performed after 24 h of pro‐inflammatory stimulus, followed by 3 days of cotreating cells with sex hormones in addition to pro‐inflammatory cytokines.
Jeffrey L. Hutchinson +2 more
wiley +1 more source
A comprehensive atlas of Aggrecan, Versican, Neurocan and Phosphacan expression across time in wildtype retina and in retinal degeneration [PDF]
, 2022 Ayako Matsuyama +4 more
openalex +1 more source