Results 131 to 140 of about 36,790 (258)

Proteolysis at the extracellular matrix interface: Molecular architects and regulators in health and disease

open access: yesThe FEBS Journal, EarlyView.
The extracellular matrix (ECM) is a dynamic scaffold that orchestrates tissue architecture and cellular communication. A critical but underexplored interplay between proteases and cluster of differentiation molecules (CD) governs ECM turnover and directs cell fate.
David Jurnečka   +3 more
wiley   +1 more source

Membrane‐type I metalloproteinase (MT1‐MMP): A key modifier of extracellular matrix microenvironment

open access: yesThe FEBS Journal, EarlyView.
MT1‐MMP: A cellular microenvironment modifier. MT1‐MMP is a major cellular microenvironment modifier, maintaining collagen homeostasis by degrading excess collagen (A), creating a migration path in motile cells such as cancer cells (B), modulating local microenvironmental signaling by cleaving transmembrane receptors (C), and destroying tissue ...
Yoshifumi Itoh, Masaki Inada
wiley   +1 more source

Aggrecan fragmentology – pattern of aggrecan fragments in different diseases [PDF]

open access: yesOsteoarthritis and Cartilage, 2014
Struglics, A.   +2 more
openaire   +2 more sources

Proteolytic remodelling of the extracellular matrix by pericytes

open access: yesThe FEBS Journal, EarlyView.
Pericytes are specialised perivascular cells intimately connected with endothelial cells and essential for the maintenance of vascular beds. They contribute to the formation and remodelling of the extracellular matrix by actively secreting proteases and protease inhibitors.
Tina Burkhard   +4 more
wiley   +1 more source

Thirty Years of Autologous Platelet Concentrates: From Platelet‐Rich Plasma to Platelet‐Rich Fibrin

open access: yesJournal of Periodontal Research, EarlyView.
This review highlights the 30 years of evolution of APCs, with a focus on their clinical applications and recent technological advancements. ABSTRACT Nearly three decades have now passed since autologous platelet concentrates (APCs) were introduced into clinical practice.
Richard J. Miron   +7 more
wiley   +1 more source

The Effects of Dietary Loading on Chondrocytes Transdifferentiation During Postnatal Maxillary Growth

open access: yesOrthodontics &Craniofacial Research, EarlyView.
ABSTRACT Background The mid‐palatal suture is a key growth site for transverse maxillary expansion, yet the cellular mechanisms governing its postnatal development and response to mechanical loading remain poorly defined. This study investigated the contribution of chondrocyte‐derived osteogenesis to maxillary bone formation and the influence of ...
Michael Stark   +5 more
wiley   +1 more source

Degeneration of the intervertebral disc with new approaches for treating low back pain. [PDF]

open access: yes, 2015
This review paper discusses the process of disc degeneration and the current understanding of cellular degradation in patients who present with low back pain.
Binch, AL   +3 more
core  

Oral Mucositis in Oncopediatric Patients: MTX and MMP‐1, MMP‐8, MMP‐13 Gene Polymorphisms

open access: yesOral Diseases, EarlyView.
ABSTRACT Background This study investigates the association between single‐nucleotide polymorphisms (SNPs) in the MMP‐1, MMP‐8, and MMP‐13 genes and the risk of oral mucositis development in paediatric patients with leukaemia and lymphoma who are undergoing methotrexate (MTX) treatment.
Nicole Januário Ribeiro   +6 more
wiley   +1 more source

Advantages of horizontal centrifugation of platelet‐rich fibrin in regenerative medicine and dentistry

open access: yesPeriodontology 2000, EarlyView.
Abstract The aim of this comprehensive review was to evaluate comparative studies on horizontal and fixed‐angle centrifugation methods for preparing platelet‐rich fibrin (PRF). Furthermore, additional studies utilizing horizontal PRF (H‐PRF) were systematically investigated.
Nima Farshidfar   +6 more
wiley   +1 more source

Platelet‐rich plasma (PRP) versus injectable platelet‐rich fibrin (i‐PRF): A systematic review across all fields of medicine

open access: yesPeriodontology 2000, EarlyView.
Abstract This systematic review aimed to evaluate all available evidence across all fields of medicine regarding the comparative effectiveness of platelet‐rich plasma (PRP) versus injectable platelet‐rich fibrin (i‐PRF). A comprehensive search was conducted in PubMed, Scopus, and Web of Science up to September 30, 2024.
Nima Farshidfar   +6 more
wiley   +1 more source

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