Results 151 to 160 of about 101,264 (202)

Premature Aging in Fibromyalgia

Current Aging Science, 2015
Chronic pain is highly prevalent in older adults, and until recently, was considered to be common but relatively "benign." Mounting evidence, however, suggests that some of the 116 million US adults who suffer from chronic pain are also at an increased risk for developing age-related diseases prematurely, suffering earlier cognitive and physical ...
Afton L, Hassett, Daniel J, Clauw, David A, Williams   +2 more
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Premature Aging and Alcoholism

International Journal of the Addictions, 1982
The proposition is frequently put forth in the literature dealing with alcohol abuse that the process which underlies the cognitive impairment found in chronic alcoholics is premature aging of the central nervous system (Fitzhugh et al., 1965; Kish and Cheney, 1969; Goldstein and Shelly, 1971; Smith et al., 1971; Jones and Parsons, 1972; Kleinknecht ...
W R, Leber, O A, Parsons
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Premature aging in uremia

Molecular and Cellular Biochemistry, 2006
Guanidinosuccinic acid is an aberrant metabolite isolated 40 years ago in the blood and urine of uremic subjects and a suspect in the toxicity associated with renal failure. It plays a minor role in the bleeding diathesis of uremia, contributes to the methyl group deficiency of dialysis patients, and is a factor in the premature atherosclerosis of end ...
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Etiological Factors and Premature Aging

JAMA, 1962
AGING IS an interesting subject which is receiving increasing attention in many fields. There is an ever-enlarging body of information which indicates that many of the phenomena which were previously regarded as "natural" processes resulting from old age are actually due to specific disease processes.
J M, KNOX, E G, COCKERELL, R G, FREEMAN
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Premature Birth and Age at Onset of Puberty

Epidemiology, 2012
Premature birth is associated with poor metabolic health in both sexes, potentially via earlier pubertal timing.We examined the associations of gestational age and premature birth (< 37 weeks gestation) with age at onset of puberty (Tanner stage II for breast or genitalia development).
Lam, TH, Schooling, CM, Hui, LL, Leung, GM   +3 more
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Growth Hormone and Premature Ageing

Nature, 1973
IT has often been suggested that the immune system may be involved in ageing1–4 Fabris et al.5 claim that such immune deficiencies are caused by inadequate stimulation of the lymphoid system by growth hormone (GH). They compared mice with inherited pituitary dwarfism (homozygotes for Snell's dwarf mutation, dw) with normal mice from the same stock. The
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Searching for clues to premature aging

Trends in Endocrinology & Metabolism, 2002
Hutchinson-Gilford Progeria syndrome is a rare developmental disorder affecting most of the organ systems in a manner that mimics natural aging but at a markedly accelerated rate. A recent workshop at the NIH, aimed at further understanding the aging process, took an in-depth look at this complex syndrome.
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Rejuvenating premature aging

Nature Medicine, 2008
Two commonly prescribed drugs, statins and aminobisphosphonates, may be helpful in combating the rare aging disorder, Hutchinson-Gilford progeria syndrome (pages 767–772).
Eran Meshorer, Yosef Gruenbaum
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Premature Aging

2012
Cockayne Syndrome – De Barsy Syndrome – Hallermann-Streiff Syndrome – Hutchinson-Gilford Progeria – Werner ...
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Delaying premature aging

Science, 2018
Premature Aging Cells from patients with Hutchinson-Gilford progeria syndrome (HGPS) have defects in nuclear architecture that lead to premature cellular senescence. Larrieu et al. investigated the mechanisms by which a small molecule called remodelin improves the phenotype of HGPS cells (see the Focus by Wilson).
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