Results 161 to 170 of about 99,091 (265)

Vascular age vs. chronological age in operative risk stratification. [PDF]

Front Cardiovasc Med
Sprankle K, Potestio C, Venkatasai S VJ, Matthews M, Mulligan LJ.   +4 more
europepmc   +1 more source

USP5 Stabilizes TGFBR1 to Drive Vascular Smooth Muscle Cell Senescence and Atherosclerosis

Advanced Science, EarlyView.
This study reveals that USP5 drives vascular smooth muscle cell senescence and atherosclerosis by stabilizing TGFBR1, suppressing IDH2, and promoting glycolytic reprogramming, identifying the USP5‐TGFBR1‐IDH2 axis as a potential therapeutic target. ABSTRACT Vascular smooth muscle cell (VSMC) senescence contributes importantly to atherosclerotic plaque ...
Xinhai Cui, Yuanlong Hu, Lin Lin, Lei Zhang, Chao Li, Yunlun Li   +5 more
wiley   +1 more source

The SIRT1-p53 axis drives a ferro-aging-like program and aggravates trophoblast dysfunction in preeclampsia. [PDF]

Front Aging
Hu R, Chen Z, Bian W, Zhang J, Xu X, Xiong H, Xiang S, Ding Y, Qi H, Yang H.   +9 more
europepmc   +1 more source

In Situ Programmable Modulation of Hydrogel Stiffness for Stage‐Adaptive Bone Regeneration

Advanced Science, EarlyView.
Near‐infrared (NIR) irradiation triggers Ca2+ release from thermoresponsive nanocarriers, enabling in situ stiffening of an adaptive hydrogel from a soft to a stiff state, thereby sequentially supporting mesenchymal stromal cell stemness and osteogenic differentiation for stage‐adaptive bone regeneration.
Yuxin Yang, Fan Yang, Lu Wang, Zongtai Li, Weichang Li, Xinchun Zhang   +5 more
wiley   +1 more source

Accelerated Vascular Aging in Women with Prior Preeclampsia: A Review of Epidemiology, Pathophysiological Mechanisms, and Geroprotective Strategies. [PDF]

J Clin Med
Yeo M, Kwak DW, Kim SY, Choi AY, Kwak M, Yang JI.   +5 more
europepmc   +1 more source

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

Advanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni, Qiancheng Zhang, Youhui Jiang, Huiying Yao, Chuqing Zhou, Xiaoyi Tian, Shiyingnan Gao, Jun Zhao, Xinyi Ren, Naxin Xu, Mengshan Fu, Liansheng Zhao, Xueyu Qi, Xueli Yu, Wanjun Guo, Sangmi Chung, Fan Guo, Tao Li   +17 more
wiley   +1 more source

Long-Term Consequences of Preterm Birth: A Lifespan Perspective.

Dev Neurosci
Chalak LF, Vega Ortiz N, Joukhdar J, Goss KN.   +3 more
europepmc   +1 more source

A Review of the Effects of Lifestyle Factors on Skin Aging. [PDF]

Am J Lifestyle Med
Nwaopara A, Woolery-Lloyd H.
europepmc   +1 more source

Delicate Management of Alkaline‐Substrate‐Induced Interfacial Reactions Enables High‐Efficiency and Stable Deep‐Red CsPbI3 Perovskite Light‐Emitting Diodes

Advanced Science, EarlyView.
We develop a magnesium‐doping strategy to delicately modulate the alkaline substrate‐induced reactions, ensuring high‐quality CsPbI3 perovskite emissive layers with substantially improved stability. The resultant deep‐red LEDs demonstrate a high peak external quantum efficiency of 23.62% and an exceptional half‐lifetime stability of 376 h at 20 mA cm−2,
Zhennan Tian, Jun Wu, Haifeng Zhao, Yong Yang, Zexi Chen, Tianxiang Lv, Xuehang Chen, Lei Yang, Ding Zheng, Chunyang Yin, Junsheng Yu, Sai Bai   +11 more
wiley   +1 more source

Mechanisms of inflammation in premature ovarian insufficiency and advances in therapeutic studies. [PDF]

Front Immunol
Chen Y, Xu Y, Lu Y, Li W, Tao F, Zhao Y.
europepmc   +1 more source