Results 101 to 110 of about 23,001 (200)

Az ""alacsony T3 szindróma"" kialakulásáért felelős központi idegrendszeri szabályozó mechanizmusok tanulmányozása patkányban = Central regulatory mechanisms involved in the development of the 'low T3 syndrome' [PDF]

, 2008
A pályázat fő célja az éhezés és fertőzés hatására kialakuló centrális hipotiroidizmus kialakulásáért felelős központi idegrendszeri szabályozó mechanizmusok tanulmányozása volt.
Fekete, Csaba, Liposits, Zsolt, Wittmann, Gábor   +2 more
core  

Discovery of Molecular Interactions of the Human Melanocortin-4 Receptor (hMC4R) Asp189 (D189) Amino Acid with the Endogenous G-Protein-Coupled Receptor (GPCR) Antagonist Agouti-Related Protein (AGRP) Provides Insights to AGRP's Inverse Agonist Pharmacology at the hMC4R. [PDF]

ACS Chem Neurosci, 2021
Ericson MD, Haslach EM, Schnell SM, Freeman KT, Xiang ZM, Portillo FP, Speth R, Litherland SA, Haskell-Luevano C.   +8 more
europepmc   +1 more source

The coding sequence of the ASIP gene is identical in nine wild-type coloured cattle breeds [PDF]

, 2011
The aim of this study was to ascertain the role of the Agouti signaling peptide (ASIP) gene coding region in the Agouti locus variation within wild-type coat colour in cattle.
Arranz, J.J. (J.), Fernández, Itziar, Goyache, Félix, Gómez, Enrique, Royo, L.J. (Luis), Álvarez, Isabel   +5 more
core  

Cellular and metabolic function of GIRK1 potassium channels expressed by arcuate POMC and NPY/AgRP neurons

Molecules and Cells
: It is well known that the G protein-gated inwardly rectifying K+ (GIRK) channels are critical to maintain excitability of central neurons. GIRK channels consist of 4 subunits and GIRK1/GIRK2 heterotetramers are considered to be the neuronal prototype ...
Yeeun Choi, Eun-Seon Yoo, Youjin Oh, Jong-Woo Sohn   +3 more
doaj   +1 more source

UCP2 mediates mitochondrial dynamics to induce AgRP neuronal activity

Molecular Metabolism
Objectives: The hypothalamic agouti-related protein (AgRP)- expressing neurons regulate feeding and whole-body energy homeostasis. A growing body of evidence indicates that changes in mitochondrial dynamics, such as fission and fusion, play a crucial ...
Sungho Jin, Nal Ae Yoon, Zhong-Wu Liu, Ciro Menale, Jung Dae Kim, Nadia Diano, Sabrina Diano   +6 more
doaj   +1 more source

Agouti-Related Protein [PDF]

, 2020
openaire   +1 more source

Opioidergic signaling contributes to food-mediated suppression of AgRP neurons

Cell Reports
Summary: Opioids are generally known to promote hedonic food consumption. Although much of the existing evidence is primarily based on studies of the mesolimbic pathway, endogenous opioids and their receptors are widely expressed in hypothalamic appetite
Nilufer Sayar-Atasoy, Yavuz Yavuz, Connor Laule, Chunyang Dong, Hyojin Kim, Jacob Rysted, Kyle Flippo, Debbie Davis, Iltan Aklan, Bayram Yilmaz, Lin Tian, Deniz Atasoy   +11 more
doaj   +1 more source

FTO promotes weight gain via altering Kif1a splicing and axonal vesicle trafficking in AgRP neurons

The EMBO Journal
N6-methyladenosine (m6A) is an abundant chemical RNA modification involved in the regulation of many biological processes. The m6A demethylase FTO (fat mass and obesity-associated protein) is known to affect body weight, but its systemic context and ...
Daisuke Kohno, Reika Kawabata-Iwakawa, Sotaro Ichinose, Shigetomo Suyama, Kazuto Ohashi, Winda Ariyani, Tetsushi Sadakata, Hiromi Yokota-Hashimoto, Ryosuke Kobayashi, Takuro Horii, Vina Yanti Susanti, Ayumu Konno, Haruka Tsuneoka, Chiharu Yoshikawa, Sho Matsui, Akihiro Harada, Toshihiko Yada, Izuho Hatada, Hirokazu Hirai, Masahiko Nishiyama, Tsutomu Sasaki, Tadahiro Kitamura   +21 more
doaj   +1 more source

Hypothalamic regulation of food intake : focus on the anx/anx mouse [PDF]

, 2010
The main goal of this thesis is to increase the knowledge about one of the most important tasks of the brain, the hypothalamic regulation of food intake. The hypothalamus is considered to be the brain s main center for regulation of food intake and it is
Nilsson, Ida
core  

Mouse circadian plasma leptin and active ghrelin rhythms under ad libitum and scheduled feeding [PDF]

, 2007
Thesis (M.S.) University of Alaska Fairbanks, 2007Light is the strongest timing cue for the circadian system, but non-photic cues can also entrain the master circadian clock, i.e., suprachiasmatic nuclei (SCN).
Wan, Haiting
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