Melatonin - leptin interaction and obesity-related genes
Most living organisms have circadian clocks which maintain rhythm in internal cycles of behavior, physiology, and metabolism, allowing them to anticipate the earth's 24-hour rota-tion.
Emine İnci Balkan, Bülent Gündüz
doaj +1 more source
Hypothalamic Melanocortin System on Feeding Regulation in Birds: A Review
Regulation of feed intake in chickens represents a complex homeostatic mechanism involving multiple levels of control. Understanding the regulation of feeding behavior can be a very important theme in animal production.
Takashi Bungo +2 more
doaj +1 more source
The Melanocortin System in Atlantic Salmon (Salmo salar L.) and Its Role in Appetite Control
The melanocortin system is a key neuroendocrine network involved in the control of food intake and energy homeostasis in vertebrates. Within the hypothalamus, the system comprises two main distinct neuronal cell populations that express the neuropeptides
Tharmini Kalananthan +7 more
doaj +1 more source
Epigenetic Contributions to the Relationship between Cancer and Dietary Intake of Nutrients, Bioactive Food Components, and Environmental Toxicants [PDF]
Cancer encompasses a highly heterogeneous group of diseases. It is thought that transition from promotion to progression in carcinogenesis may be driven primarily by epigenetic abnormalities.
L. Joseph Su +4 more
core +1 more source
Entwicklung der Adipositas und Neuropeptidexpression bei Melanokortin-4-Rezeptor-defizienten Mäusen unter besonderer Berücksichtigung der Haltungsbedingungen [PDF]
Der Melanokortin-4-Rezeptor-Defekt (mit einer Prävalenz von 2-6% in einem adipösen Patientenkollektiv) ist die bisher am häufigsten nachgewiesene monogenetische Form der Adipositas beim Menschen.
Schmidt, Ingrid (Prof. Dr.) +1 more
core +1 more source
Structural and Molecular Evolutionary Analysis of Agouti and Agouti-Related Proteins
Agouti (ASIP) and Agouti-related protein (AgRP) are endogenous antagonists of melanocortin receptors that play critical roles in the regulation of pigmentation and energy balance, respectively, and which arose from a common ancestral gene early in vertebrate evolution.
Jackson, Pilgrim J. +6 more
openaire +2 more sources
Determinants of body weight regulation in humans
Body weight is regulated by the ability of hypothalamic neurons to orchestrate behavioral, endocrine and autonomic responses via afferent and efferent pathways to the brainstem and the periphery.
Milene Moehlecke +5 more
doaj +1 more source
CNS Control of Glucose Metabolism: Response to Environmental Challenges [PDF]
Over the last 15 years, considerable work has accumulated to support the role of the CNS in regulating postprandial glucose levels. As discussed in the first section of this review, the CNS receives and integrates information from afferent neurons ...
Arble, Deanna M., Sandoval, Darleen A.
core +1 more source
Astrocytes: New Targets of Melanocortin 4 Receptor Actions [PDF]
Astrocytes exert a wide variety of functions with paramount importance in brain physiology. After injury or infection, astrocytes become reactive and they respond by producing a variety of inflammatory mediators that help maintain brain homeostasis. Loss
Carniglia, Lila +4 more
core +1 more source
Hypothalamic melanortin receptor (MCR) activation inhibits appetite. Neuropeptide Y (NPY) and Agouti Related Protein (AgRP) are coexpressed in some hypothalamic neurons and stimulate feeding, NPY via inhibition of MCR-expressing neurons, and AgRP via ...
E. N. Makarova +2 more
doaj +1 more source

