Results 91 to 100 of about 23,001 (200)

Editorial: Glucosensing impact on glucose metabolism: From fish to mammals

Frontiers in Endocrinology, 2023
Xiao-Chen Yuan, Ya-Xiong Tao
doaj   +1 more source

RESTING PLASMA AgRP LEVELS RESPONSE TO EXERCISE-CONJUGATED DIET AND ONLY DIET IN OVERWEIGHT AND OBESE SEDENTARY FEMALES [PDF]

, 2012
Agouti-related peptide (AgRP) is an orexigenic neuropeptide produced mainly in the arcuate nucleus (ARC) of the hypothalamus, which leads to positive energy balance.
Amir Rashidlamir, Firoozeh Delphan, Mahmoud Delphan   +2 more
core  

Feeding Stimulates Sphingosine-1-Phosphate Mobilization in Mouse Hypothalamus. [PDF]

, 2019
Previous studies have shown that the sphingolipid-derived mediator sphingosine-1-phosphate (S1P) reduces food intake by activating G protein-coupled S1P receptor-1 (S1PR1) in the hypothalamus.
Misto, Alessandra, Piomelli, Daniele, Realini, Natalia, Vozella, Valentina   +3 more
core   +1 more source

Adrenalectomy alters the sensitivity of the central nervous system melanocortin system [PDF]

, 2003
Removal of adrenal steroids by adrenalectomy (ADX) reduces food intake and body weight in rodents and prevents excessive weight gain in many genetic and dietary models of obesity. Thus, glucocorticoids appear to play a key role to promote positive energy
Clegg, DJ, Drazen, Deborah L., Drazen, DL, Schwartz, Michael W., Schwartz, MW, Seeley, Randy J., Seeley, RJ, van Dijk, G, Woods, SC, Woods, Stephen C., Wortman, Matthew D., Wortman, MD   +11 more
core   +2 more sources

Feeding Rhythm-Induced Hypothalamic Agouti-Related Protein Elevation via Glucocorticoids Leads to Insulin Resistance in Skeletal Muscle. [PDF]

Int J Mol Sci, 2021
Shiuchi T, Otsuka A, Shimizu N, Chikahisa S, Séi H.   +4 more
europepmc   +1 more source

Effects of Agouti Related Protein and Androgens on Growth

Journal of Applied Sciences, 2003
A dominant mutation at the agouti locus on mouse chromosome 2 is a promoter of overeating and increased linear growth. Agouti related protein, which can be produced using bacteria can be used to reproduce the same growing effect. Androgens are known to promote leanness and increased growth.
openaire   +1 more source

Emerging Signaling Pathway in Arcuate Feeding-Related Neurons: Role of the Acbd7

Frontiers in Neuroscience, 2017
The understanding of the mechanisms whereby energy balance is regulated is essential to the unraveling of the pathophysiology of obesity. In the last three decades, focus was put on the metabolic role played by the hypothalamic neurons expressing ...
Damien Lanfray, Denis Richard
doaj   +1 more source

The association between neuropeptide levels, lifestyle and BMI in postpartum women – a follow-up study [PDF]

, 2017
“The association between neuropeptide levels, lifestyle and BMI in postpartum women – a follow-up study” Author: Ameli Ingemansson. Supervisor: Ulrika Andersson Hall.
Ingemansson, Ameli
core  

Sucrose overconsumption impairs AgRP neuron dynamics and promotes palatable food intake

Cell Reports
Summary: Rapid gut-brain communication is critical to maintain energy balance and is disrupted in diet-induced obesity. In particular, the role of carbohydrate overconsumption in the regulation of interoceptive circuits in vivo requires further ...
Carolyn M. Lorch, Nikolas W. Hayes, Jessica L. Xia, Stefan W. Fleps, Hayley E. McMorrow, Haley S. Province, Joshua A. Frydman, Jones G. Parker, Lisa R. Beutler   +8 more
doaj   +1 more source

Anorexigenic and Orexigenic Hormone Modulation of Mammalian Target of Rapamycin Complex 1 Activity and the Regulation of Hypothalamic Agouti-Related Protein mRNA Expression

Neurosignals, 2012
Activation of mammalian target of rapamycin 1 (mTORC1) by nutrients, insulin and leptin leads to appetite suppression (anorexia). Contrastingly, increased AMP-activated protein kinase (AMPK) activity by ghrelin promotes appetite (orexia).
Kenneth R. Watterson, Dawn Bestow, Jennifer Gallagher, D. Lee Hamilton, Fiona B. Ashford, Paul J. Meakin, Michael L.J. Ashford   +6 more
doaj   +1 more source