Results 61 to 70 of about 23,001 (200)

Hypothalamic mTOR signaling mediates the orexigenic action of ghrelin.

PLoS ONE, 2012
Current evidence suggests that ghrelin, a stomach derived peptide, exerts its orexigenic action through specific modulation of Sirtuin1 (SIRT1)/p53 and AMP-activated protein kinase (AMPK) pathways, which ultimately increase the expression of agouti ...
Luís Martins, Diana Fernández-Mallo, Marta G Novelle, María J Vázquez, Manuel Tena-Sempere, Rubén Nogueiras, Miguel López, Carlos Diéguez   +7 more
doaj   +1 more source

Activity Based Anorexia as an Animal Model for Anorexia Nervosa–A Systematic Review [PDF]

, 2019
Anorexia nervosa (AN) is a severe eating disorder affecting around 1 per 100 persons. However, the knowledge about its underlying pathophysiology is limited.
Schalla, Martha A., Stengel, Andreas
core   +1 more source

Effect of eight weeks aerobic exercise on plasma level of agouti-related protein, glycated hemoglobin and glucose in non-active type II diabetic women

مجله دانشگاه علوم پزشکی گرگان, 2015
Background and Objective: Diabetes mellitus is the most common type of metabolic diseases which is characterized with hyperglycemia due to implicit or relative insulin deficiency. Diabetes mellitus is acutely related to obesity.
Ghiasi E, Dabbagh Manesh MH, Daryanoosh F, Nazemzadeghan Gh   +3 more
doaj  

Mammalian comparative sequence analysis of the Agrp locus. [PDF]

PLoS ONE, 2007
Agouti-related protein encodes a neuropeptide that stimulates food intake. Agrp expression in the brain is restricted to neurons in the arcuate nucleus of the hypothalamus and is elevated by states of negative energy balance.
Christopher B Kaelin, Gregory M Cooper, Arend Sidow, Gregory S Barsh   +3 more
doaj   +1 more source

Pathophysiology of melanocortin receptors and their accessory proteins. [PDF]

, 2018
The melanocortin receptors (MCRs) and their accessory proteins (MRAPs) are involved in regulation of a diverse range of endocrine pathways. Genetic variants of these components result in phenotypic variation and disease. The MC1R is expressed in skin and
A.J.L. Clark, Anderson, Asai, Balthasar, Begriche, Benjannet, Bishop, Box, Buggy, Bultman, Butler, Butler, Böhm, Chakraborty, Chaly, Chan, Chan, Chan, Chen, Chen, Chen, Cheung, Chida, Chung, Chung, Clark, Clark, Clark, Clark, Coll, Collet, Cone, Cone, Cooray, Cooray, Cooray, Cui, D'Orazio, do Carmo, Elias, Enriori, Farooqi, Feng, Flier, Friedman, Gee, Ghamari-Langroudi, Girardet, Gonzalez-Rey, Gorrigan, Greenfield, Huszar, Jarrett, Kievit, Kim, L.F. Chan, Landi, Lee, Lee, Lembertas, Lim, Lovett, Lowry, Lu, Manceau, Markison, Marks, Marsh, Martinelli, Metherell, Metherell, Miller, Mirshahi, Morgan, Morgan, Morgan, Mountjoy, Mountjoy, Ni, Nimura, Novoselova, O'Rahilly, Ogawa, Ollmann, Padilla, Palmer, Pasquali, Pelleymounter, Raadsheer, Rached, Raimondi, Robbins, Robles-Espinoza, Rodrigues, Roselli-Rehfuss, Rouault, Roy, Schauer, Scott, Sebag, Sebag, Shen, Shenker, Simamura, Smith, Smith, Sohn, Srisai, Swords, T.V. Novoselova, Tao, Turan, Ulrich-Lai, Vaisse, Valverde, Vinson, Webb, Webb, Weber, Williams, Xu, Xu, Yang, Yeo, Young, Zhang, Zhang   +126 more
core   +2 more sources

The relationship between Agouti related protein and leptin in patients with methamphetamine use disorder

Middle East Current Psychiatry
Background Appetite regulation involves a complex interplay between peripheral signals and central hypothalamic neuropeptides. Two key hormones in this mechanism are leptin, an adipocyte-derived hormone that suppresses food intake, and Agouti-Related ...
Nehal Mostafa, Wael M. Fathy, Nada El Sayed Selim, Eman Ahmed Abdullah   +3 more
doaj   +1 more source

Arcuate AgRP neurons and the regulation of energy balance

Frontiers in Endocrinology, 2012
The arcuate nucleus of the hypothalamus contains at least two crucial populations of neurons that continuously monitor signals reflecting energy status and promote the appropriate behavioral and metabolic responses to changes in energy demand.
Céline eCansell, Raphaël G.P Denis, Aurélie eJoly-Amado, Julien eCastel, Julien eCastel, Serge H Luquet, Serge H Luquet   +6 more
doaj   +1 more source

The differential expression of MC1R regulators in dorsal and ventral quail plumages during embryogenesis: Implications for plumage pattern formation. [PDF]

PLoS ONE, 2017
Melanin pigmentation patterns are ubiquitous in animals and function in crypsis, physical protection, thermoregulation and signalling. In vertebrates, pigmentation patterns formed over large body regions as well as within appendages (hair/feathers) may ...
Thanh-Lan Gluckman, Nicholas I Mundy
doaj   +1 more source

Liver ERα regulates AgRP neuronal activity in the arcuate nucleus of female mice

Scientific Reports, 2017
Recent work revealed the major role played by liver Estrogen Receptor α (ERα) in the regulation of metabolic and reproductive functions. By using mutant mice with liver-specific ablation of Erα, we here demonstrate that the hepatic ERα is essential for ...
Valeria Benedusi, Sara Della Torre, Nico Mitro, Donatella Caruso, Alessandra Oberto, Claire Tronel, Clara Meda, Adriana Maggi   +7 more
doaj   +1 more source

Physiopathological Implications of 7TM Receptors [PDF]

, 2010
Seven-transmembrane (7TM) receptors are one of the most important proteins involved in perception of extracellular stimuli and regulation of variety of intracellular signaling pathways.
Cygankiewicz, Adam
core   +2 more sources