Results 61 to 70 of about 339,684 (208)

The high glycemic index diet was an independent predictor to explain changes in agouti-related protein in obese adolescents

open access: yesNutrición Hospitalaria, 2014
The high glycemic index diet was an independent predictor to explain changes in agouti-related protein in obese adolescents. Background & Aims: The role of diet glycemic index (GI) in the control of orexigenic and anorexigenic factors of the energy ...
Bárbara Dal Molin Netto   +9 more
doaj   +1 more source

The differential expression of MC1R regulators in dorsal and ventral quail plumages during embryogenesis: Implications for plumage pattern formation. [PDF]

open access: yesPLoS ONE, 2017
Melanin pigmentation patterns are ubiquitous in animals and function in crypsis, physical protection, thermoregulation and signalling. In vertebrates, pigmentation patterns formed over large body regions as well as within appendages (hair/feathers) may ...
Thanh-Lan Gluckman, Nicholas I Mundy
doaj   +1 more source

Canonical and non‐canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney   +4 more
wiley   +1 more source

Gene structure of the goldfish agouti-signaling protein: A putative role in the dorsal-ventral pigment pattern of fish

open access: yes, 2005
One of the most successful chromatic adaptations in vertebrates is the dorsal-ventral pigment pattern in which the dorsal skin is darkly colored, whereas the ventrum is light.
Schioth, H.B.   +3 more
core   +1 more source

Liver ERα regulates AgRP neuronal activity in the arcuate nucleus of female mice

open access: yesScientific Reports, 2017
Recent work revealed the major role played by liver Estrogen Receptor α (ERα) in the regulation of metabolic and reproductive functions. By using mutant mice with liver-specific ablation of Erα, we here demonstrate that the hepatic ERα is essential for ...
Valeria Benedusi   +7 more
doaj   +1 more source

Arcuate AgRP neurons and the regulation of energy balance

open access: yesFrontiers in Endocrinology, 2012
The arcuate nucleus of the hypothalamus contains at least two crucial populations of neurons that continuously monitor signals reflecting energy status and promote the appropriate behavioral and metabolic responses to changes in energy demand.
Céline eCansell   +6 more
doaj   +1 more source

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor   +4 more
wiley   +1 more source

Association of Inflammatory and Cardiovascular Proteomics Biomarkers With Indices of Heart Rate Variability in the General Population: KORA S4/FF4 Study

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background We sought to investigate the association between circulating inflammatory and cardiovascular proteomics biomarkers and cardiac autonomic nervous dysfunction–sensitive heart rate variability indices.
Kolade Oluwagbemigun   +14 more
doaj   +1 more source

Role of hormonal and inflammatory alterations in obesity-related reproductive dysfunction at the level of the hypothalamic-pituitary-ovarian axis

open access: yesReproductive Biology and Endocrinology, 2018
Background Besides being a risk factor for multiple metabolic disorders, obesity could affect female reproduction. While increased adiposity is associated with hormonal changes that could disrupt the function of the hypothalamus and the pituitary ...
Michelle Goldsammler   +2 more
doaj   +1 more source

Ovarian hormones and high‐fat diet duration distinctively modulate hypothalamic chemokine profile

open access: yesJournal of Neuroendocrinology, Volume 38, Issue 7, July 2026.
Abstract Excessive intake of saturated fats triggers inflammation in the hypothalamus, a key regulator of energy balance. In the chronic phase of this inflammatory response, bone marrow‐derived and lymphoid cells are chemoattracted to this region, partially mitigating high‐fat diet (HFD)‐induced metabolic impairments.
Alexia Guimaraes Batista Augusto   +8 more
wiley   +1 more source

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