Results 41 to 50 of about 23,001 (200)
eLife, 2023 Fatty acid amide hydrolase (FAAH) degrades the endocannabinoid anandamide. A polymorphism in FAAH (FAAH C385A) reduces FAAH expression, increases anandamide levels, and increases the risk of obesity.
Georgia Balsevich +14 more
doaj +1 more source
Novel hypophysiotropic AgRP2 neurons and pineal cells revealed by BAC transgenesis in zebrafish [PDF]
, 2017 The neuropeptide agouti-related protein (AgRP) is expressed in the arcuate nucleus of the mammalian hypothalamus and plays a key role in regulating food consumption and energy homeostasis.
Buchshtab, A +5 more
core +1 more source
PGC-1α expression in murine AgRP neurons regulates food intake and energy balance
Molecular Metabolism, 2016 Objective: Food intake and whole-body energy homeostasis are controlled by agouti-related protein (AgRP) and pro-opiomelanocortin (POMC) neurons located in the arcuate nucleus of the hypothalamus.
Jonathan F. Gill +3 more
doaj +1 more source
Detecting epistasis via Markov bases [PDF]
, 2010 Rapid research progress in genotyping techniques have allowed large genome-wide association studies. Existing methods often focus on determining associations between single loci and a specific phenotype.
Malaspinas, Anna-Sapfo, Uhler, Caroline
core +1 more source
Maternal nutritional status, C1 metabolism and offspring DNA methylation: a review of current evidence in human subjects. [PDF]
, 2011 : Evidence is growing for the long-term effects of environmental factors during early-life on later disease susceptibility. It is believed that epigenetic mechanisms (changes in gene function not mediated by DNA sequence alteration), particularly DNA ...
Cox, SE +4 more
core +4 more sources
Effect of endurance training on plasma levels of AGRP and HOMA-IR in diabetic rats
Turkish Journal of Kinesiology, 2017 The hypothalamus is a strong central controller of appetite that secretes different neuropeptides including AGRP. Plasma levels of AGRP are effective in controlling obesity and hunger.
Javad Mehrabani +4 more
doaj +2 more sources
Genetic characterization of coat color genes in Brazilian Crioula sheep from a conservation nucleus [PDF]
Pesquisa Agropecuária Brasileira, 2017 : The objective of this work was to identify single nucleotide polymorphisms (SNPs) in resequencing data from MC1R, ASIP, and TYRP1 genes derived from Crioula sheep (Ovis aris) with different coat colors.
Lilian Cristina Gomes Cavalcanti +7 more
doaj +1 more source
BMC Medical Genetics, 2009 Background The agouti related protein (AGRP) is an endogenous antagonist of the melanocortin 4 receptor and is one of the most potent orexigenic factors.
Ignatovica Vita +5 more
doaj +1 more source
The role of the Agouti-Related Protein in energy balance regulation. [PDF]
Cell Mol Life Sci, 2008 The Agouti-Related Protein (AgRP) is a powerful orexigenic peptide that increases food intake when ubiquitously overexpressed or when administered centrally. AgRP-deficiency, on the other hand, leads to increased metabolic rate and a longer lifespan when mice consume a high fat diet.
Ilnytska O, Argyropoulos G.
europepmc +4 more sources
Metabolic effects of diets differing in glycaemic index depend on age and endogenous GIP [PDF]
, 2009 Aims/hypothesis High- vs low-glycaemic index (GI) diets unfavourably affect body fat mass and metabolic markers in rodents. Different effects of these diets could be age-dependent, as well as mediated, in part, by carbohydrate-induced stimulation of ...
A. Abdelrahman +45 more
core +1 more source