Results 41 to 50 of about 12,122 (173)

Effect of endurance training on plasma levels of AGRP and HOMA-IR in diabetic rats

Turkish Journal of Kinesiology, 2017
The hypothalamus is a strong central controller of appetite that secretes different neuropeptides including AGRP. Plasma levels of AGRP are effective in controlling obesity and hunger.
Javad Mehrabani, Maryam Sedighianrad, Nasrin Ramezani, Hadi Nobari, Reza Bagheri   +4 more
doaj   +2 more sources

Genetic characterization of coat color genes in Brazilian Crioula sheep from a conservation nucleus [PDF]

Pesquisa Agropecuária Brasileira, 2017
: The objective of this work was to identify single nucleotide polymorphisms (SNPs) in resequencing data from MC1R, ASIP, and TYRP1 genes derived from Crioula sheep (Ovis aris) with different coat colors.
Lilian Cristina Gomes Cavalcanti, José Carlos Ferrugem Moraes, Danielle Assis de Faria, Concepta Margaret McManus, Alcebiades Renato Nepomuceno, Carlos José Hoff de Souza, Alexandre Rodrigues Caetano, Samuel Rezende Paiva   +7 more
doaj   +1 more source

Association between a rare SNP in the second intron of human Agouti related protein gene and increased BMI

BMC Medical Genetics, 2009
Background The agouti related protein (AGRP) is an endogenous antagonist of the melanocortin 4 receptor and is one of the most potent orexigenic factors.
Ignatovica Vita, Pirags Valdis, Kapa Ivo, Kalnina Ineta, Schiöth Helgi B, Klovins Janis   +5 more
doaj   +1 more source

Neuroendocrine and Molecular Interactions in Eating Disorders [PDF]

Psikiyatride Güncel Yaklaşımlar, 2014
There are three basic pillars for the development of eating disorders: genetic predisposition, neuro-endocrine-molecular changes in the brain and metabolic response to it.
Selma Bozkurt Zincir
doaj   +1 more source

Strategies for inducing diabetes in laboratory animals: Advances from chemical, surgical, immunologic, dietary, and genetic approaches

Animal Models and Experimental Medicine, EarlyView.
This review summarizes the principal experimental approaches used to induce diabetes in animal models. Strategies include chemical agents (streptozotocin, alloxan, dithizone, gold thioglucose), dietary interventions (high‐fat and high‐sugar diets), surgical methods (total or partial pancreatectomy), genetic models (db/db, ob/ob, Goto‐Kakizaki [GK ...
Milad Faraji, Maedeh Faraji, Nasrin Kazemipour   +2 more
wiley   +1 more source

Facing the Challenges of Neuropeptide Gene Knockouts: Why Do They Not Inhibit Reproduction in Adult Teleost Fish?

Frontiers in Neuroscience, 2018
Genetic manipulation of teleost endocrine systems started with transgenic overexpression of pituitary growth hormone. Such strategies enhance growth and reduce fertility, but the fish still breed.
Vance L. Trudeau
doaj   +1 more source

Effects of low energy availability on female reproductive function

Reproductive Medicine and Biology, 2022
Background It is known that metabolic and nutritional disturbances induce reproductive dysfunction in females. The main cause of these alterations is reduced gonadotrophin‐releasing hormone (GnRH) secretion from the hypothalamus, and the underlying ...
Takeshi Iwasa, Saki Minato, Junki Imaizumi, Atsuko Yoshida, Takako Kawakita, Kanako Yoshida, Yuri Yamamoto   +6 more
doaj   +1 more source

The liver‐brain axis: A multidimensional regulatory network implicated in Alzheimer's disease pathogenesis and clinical implications

Animal Models and Experimental Medicine, EarlyView.
Schematic diagram of the core pathways of the liver‐brain axis in regulating AD. The liver regulates cerebral Aβ deposition, tau phosphorylation, and neuroinflammation through pathways such as metabolic detoxification (urea cycle, ketone body metabolism, glutathione antioxidant system), molecular secretion (APOE, CRP, FGF21, IGF‐1), and Aβ clearance ...
Ning Zhang, Wei Chen, Meng Wang
wiley   +1 more source

Plasma Levels of Agouti-Related Protein Are Increased in Obese Men [PDF]

The Journal of Clinical Endocrinology & Metabolism, 2001
To investigate the relationship between peripheral blood levels of agouti-related protein (AGRP) and various parameters of obesity, we measured the plasma level of AGRP in 15 obese and 15 nonobese men and evaluated its relationship with body mass index (BMI), body fat weight, and visceral, sc, and total fat areas measured by computed tomography ...
A, Katsuki, Y, Sumida, E C, Gabazza, S, Murashima, T, Tanaka, M, Furuta, R, Araki-Sasaki, Y, Hori, K, Nakatani, Y, Yano, Y, Adachi   +10 more
openaire   +2 more sources

The association between neural crest‐derived glia and melanocyte lineages throughout development and disease

Developmental Dynamics, EarlyView.
Abstract Neural crest cells are a transient cell population that emerges from the dorsal neural tube during neurulation and migrates extensively throughout the embryo. Among their diverse derivatives, glial cells (such as Schwann and satellite ganglionic cells) and melanocytes represent two major lineages. In vitro studies suggested they share a common
Chaya Kalcheim
wiley   +1 more source