Results 31 to 40 of about 12,122 (173)
Frontiers in Systems Neuroscience, 2015 A major question in systems neuroscience is how a single population of neurons can interact with the rest of the brain to orchestrate complex behavioral states. The hypothalamus contains many such discrete neuronal populations that individually regulate
Allison eGraebner +2 more
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Effect of 24 h Fasting on Gene Expression of AMPK, Appetite Regulation Peptides and Lipometabolism Related Factors in the Hypothalamus of Broiler Chicks [PDF]
Asian-Australasian Journal of Animal Sciences, 2012 The 5’-adenosine monophosphate-activated protein kinase (AMPK) is a key part of a kinase-signaling cascade that acts to maintain energy homeostasis. The objective of this experiment was to investigate the possible effects of fasting and refeeding on the ...
Liu Lei, Zhu Lixian
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The Journal of Poultry Science, 2022 Previous studies in mammalian obesity models have suggested that central transforming growth factor-β (TGF-β) controls the gene expression of appetite-regulating neuropeptides and peripheral energy metabolism.
Takaoki Saneyasu +5 more
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AgRP neurons are not indispensable for body weight maintenance in adult mice
Cell Reports, 2023 Summary: In addition to their role in promoting feeding and obesity development, hypothalamic arcuate agouti-related protein/neuropeptide Y (AgRP/NPY) neurons are widely perceived to be indispensable for maintaining normal feeding and body weight in ...
Jing Cai +9 more
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Role of Agouti-Related Protein-Expressing Neurons in Lactation [PDF]
Endocrinology, 2007 Hypothalamic neurons that express agouti-related protein (AgRP) and neuropeptide Y (NPY) are thought to be important for regulation of feeding, especially under conditions of negative energy balance. The expression of NPY and AgRP increases during lactation and may promote the hyperphagia that ensues.
Colin T, Phillips, Richard D, Palmiter
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Psychiatry and Clinical Psychopharmacology, 2019 OBJECTIVES: Bipolar disorder (BD) is a chronic psychiatric disorder with a high prevalence of obesity. There are a number of hypotheses regarding the association between obesity and BD.
Evrim Özkorumak Karagüzel +5 more
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Cannabinoid type 1 receptor-containing axons innervate NPY/AgRP neurons in the mouse arcuate nucleus
Molecular Metabolism, 2017 Objectives: Phytocannabinoids, such as THC and endocannabinoids, are well known to promote feeding behavior and to control energy metabolism through cannabinoid type 1 receptors (CB1R).
Yury M. Morozov +3 more
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eLife, 2023 Fatty acid amide hydrolase (FAAH) degrades the endocannabinoid anandamide. A polymorphism in FAAH (FAAH C385A) reduces FAAH expression, increases anandamide levels, and increases the risk of obesity.
Georgia Balsevich +14 more
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PGC-1α expression in murine AgRP neurons regulates food intake and energy balance
Molecular Metabolism, 2016 Objective: Food intake and whole-body energy homeostasis are controlled by agouti-related protein (AgRP) and pro-opiomelanocortin (POMC) neurons located in the arcuate nucleus of the hypothalamus.
Jonathan F. Gill +3 more
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Contribution of Melanocortin Receptor Exoloops to Agouti-related Protein Binding [PDF]
Journal of Biological Chemistry, 1999 Agouti-related protein (AGRP) is an endogenous antagonist of melanocortin action that functions in the hypothalamic control of feeding behavior. Although previous studies have shown that AGRP binds three of the five known subtypes of melanocortin receptor, the receptor domains participating in binding and the molecular interactions involved are ...
Y K, Yang +5 more
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