Results 51 to 60 of about 339,684 (208)
Effects of low energy availability on female reproductive function
Reproductive Medicine and Biology, 2022 Background It is known that metabolic and nutritional disturbances induce reproductive dysfunction in females. The main cause of these alterations is reduced gonadotrophin‐releasing hormone (GnRH) secretion from the hypothalamus, and the underlying ...
Takeshi Iwasa +6 more
doaj +1 more source
Integrative Zoology, EarlyView.Social rank in greater long‐tailed hamsters (Tscherskia triton) shapes gut microbiota composition and metabolite profiles. Dominant males exhibit a “high‐vigilance, metabolically activated” phenotype, with elevated aggression and specific gut microbiota enriched in energy‐harvesting taxa and fecal queuine.
Da Zhang, Xiaoming Xu, Zhibin Zhang
wiley +1 more source
Agouti: From mouse to man, from skin to fat
, 2002 The agouti protein regulates pigmentation in the mouse hair follicle producing a black hair with a subapical yellow band. Its effect on pigmentation is achieved by antagonizing the binding of alpha-melanocyte stimulating hormone (alpha-MSH) to ...
van Daal, Angela M. +3 more
core +1 more source
Hypothalamic mTOR signaling mediates the orexigenic action of ghrelin.
PLoS ONE, 2012 Current evidence suggests that ghrelin, a stomach derived peptide, exerts its orexigenic action through specific modulation of Sirtuin1 (SIRT1)/p53 and AMP-activated protein kinase (AMPK) pathways, which ultimately increase the expression of agouti ...
Luís Martins +7 more
doaj +1 more source
Amylin analogues as a novel perspective in anti‐obesity therapy
British Journal of Pharmacology, EarlyView.Abstract Public health systems face a major challenge because of the worldwide obesity epidemic. The number of obese individuals has increased dramatically and, even in Switzerland which may be considered a relatively “lean” country, the numbers are alarmingly high and have reached almost 50% of the adult population.
Thomas A. Lutz
wiley +1 more source
Informal supply chains of wild meat from rural Amazonia and food security in an urban center
Conservation Biology, EarlyView.Abstract Iquitos, the most populated city in the Peruvian Amazon, is a hub in the regional supply chain of wild meat and supplies urban consumers. Studies on wild meat consumption have focused primarily on markets, limiting the scope of species considered to those that are economically valuable and potential inferences from those data.
Fiorella Briceño Huerta +3 more
wiley +1 more source
The melanocortin receptors and their accessory proteins. [PDF]
, 2013 The five melanocortin receptors (MCRs) named MC1R-MC5R have diverse physiological roles encompassing pigmentation, steroidogenesis, energy homeostasis and feeding behavior as well as exocrine function.
Adrian J. L. Clark +12 more
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Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction
Obesity Reviews, EarlyView.Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey +7 more
wiley +1 more source
Mammalian comparative sequence analysis of the Agrp locus. [PDF]
PLoS ONE, 2007 Agouti-related protein encodes a neuropeptide that stimulates food intake. Agrp expression in the brain is restricted to neurons in the arcuate nucleus of the hypothalamus and is elevated by states of negative energy balance.
Christopher B Kaelin +3 more
doaj +1 more source
Middle East Current PsychiatryBackground Appetite regulation involves a complex interplay between peripheral signals and central hypothalamic neuropeptides. Two key hormones in this mechanism are leptin, an adipocyte-derived hormone that suppresses food intake, and Agouti-Related ...
Nehal Mostafa +3 more
doaj +1 more source