Agouti Related Protein (AgRP) is Upregulated in Cushing's Syndrome
Experimental and Clinical Endocrinology & Diabetes, 2005 Alpha melanocyte-stimulating hormone (alpha-MSH) is an agonist at the melanocortin 3 (MC3-R) and melanocortin 4 (MC4-R) receptors. Alpha-MSH stimulates corticosterone release from rat and human adrenal cells. Patients with Cushing's syndrome have elevated levels of serum alpha-MSH.
Dhillo, WS +8 more
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Neuroendocrine and Molecular Interactions in Eating Disorders [PDF]
Psikiyatride Güncel Yaklaşımlar, 2014 There are three basic pillars for the development of eating disorders: genetic predisposition, neuro-endocrine-molecular changes in the brain and metabolic response to it.
Selma Bozkurt Zincir
doaj +1 more source
Nutrition, Epigenetics, and Diseases [PDF]
, 2014 Increasing epidemiological evidence suggests that maternal nutrition and environmental exposure early in development play an important role in susceptibility to disease in later life.
Jang, Hyeran, Serra, Carlo
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The Emerging Role of Ten-Eleven Translocation 1 in Epigenetic Responses to Environmental Exposures. [PDF]
, 2020 Mounting evidence from epidemiological studies and animal models has linked exposures to environmental factors to changes in epigenetic markers, especially in DNA methylation.
Brown, Anthony P, Ji, Hong, Zhu, Tao
core
Frontiers in Neuroscience, 2018 Genetic manipulation of teleost endocrine systems started with transgenic overexpression of pituitary growth hormone. Such strategies enhance growth and reduce fertility, but the fish still breed.
Vance L. Trudeau
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Effects of low energy availability on female reproductive function
Reproductive Medicine and Biology, 2022 Background It is known that metabolic and nutritional disturbances induce reproductive dysfunction in females. The main cause of these alterations is reduced gonadotrophin‐releasing hormone (GnRH) secretion from the hypothalamus, and the underlying ...
Takeshi Iwasa +6 more
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Gene expression analysis indicates CB1 receptor upregulation in the hippocampus and neurotoxic effects in the frontal cortex 3 weeks after single-dose MDMA administration in Dark Agouti rats. [PDF]
, 2013 BACKGROUND: 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") is a widely used recreational drug known to impair cognitive functions on the long-run.
A Alttoa +95 more
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Plasma Levels of Agouti-Related Protein Are Increased in Obese Men [PDF]
The Journal of Clinical Endocrinology & Metabolism, 2001 To investigate the relationship between peripheral blood levels of agouti-related protein (AGRP) and various parameters of obesity, we measured the plasma level of AGRP in 15 obese and 15 nonobese men and evaluated its relationship with body mass index (BMI), body fat weight, and visceral, sc, and total fat areas measured by computed tomography ...
A, Katsuki +10 more
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Hauptgeneffekt auf die Entstehung exzremer Adipositas bei Kindern und Jugendlichen durch funktionell relevante Mutationen des Melanocortin 4 Rezeptor-Gens [PDF]
, 2004 Adipositas stellt in unserer Gesellschaft zunehmend nicht nur ein Problem für die Gesundheit und Lebensqualität des Betroffenen, sondern auch eine sozioökonomische Belastung für die Gemeinschaft dar.
Hebebrand, Prof. Dr. Johannes +1 more
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Hedgehog Pathway Activation Alters Ciliary Signaling in Primary Hypothalamic Cultures [PDF]
, 2019 Primary cilia dysfunction has been associated with hyperphagia and obesity in both ciliopathy patients and mouse models of cilia perturbation. Neurons throughout the brain possess these solitary cellular appendages, including in the feeding centers of ...
Antonellis, Patrick J. +7 more
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