Results 181 to 190 of about 959,384 (214)
Some of the next articles are maybe not open access.
Journal of Mammalian Evolution, 2010
Agouti is a common pigmentation phenotype in mammals including primates. Mutations in the agouti signaling protein gene (ASIP) are known to result in non-agouti black hairs in laboratory mice. It is still unclear whether sequence variation in ASIP is linked with the agouti/non-agouti phenotypes in macaques (Genus Macaca). To address this issue, we have
Takayoshi Shotake +2 more
exaly +2 more sources
Agouti is a common pigmentation phenotype in mammals including primates. Mutations in the agouti signaling protein gene (ASIP) are known to result in non-agouti black hairs in laboratory mice. It is still unclear whether sequence variation in ASIP is linked with the agouti/non-agouti phenotypes in macaques (Genus Macaca). To address this issue, we have
Takayoshi Shotake +2 more
exaly +2 more sources
Agouti signaling protein and other factors modulating differentiation and proliferation of immortal melanoblasts [PDF]
Developmental Dynamics, 2001 AbstractThe melanocyte lineage potentially forms an attractive model system for studies in cell differentiation, developmental genetics, cell signaling, and melanoma, because differentiated cells produce the visible pigment melanin. Immortal lines of murine melanoblasts (melanocyte precursors) have been described previously, but induction of ...
Elena V Sviderskaya +2 more
exaly +3 more sources
Bioactive Motifs of Agouti Signal Protein
Experimental Cell Research, 2000The switch between the synthesis of eu- and pheomelanins is modulated by the interaction of two paracrine signaling molecules, alpha-melanocyte stimulating hormone (MSH) and agouti signal protein (ASP), which interact with melanocytes via the MSH receptor (MC1R).
V M, Virador +4 more
openaire +2 more sources
Agouti‐Related Proteins (AGRPs) and Agouti‐Signaling Peptide (ASIP) in Fish and Chicken
Annals of the New York Academy of Sciences, 2005Abstract: We performed an intensive search on sequence databases to identify orthologues of ASIP and AGRP peptides in a number of different species, revealing a number of genomic fragments coding for the C‐terminal part of agouti‐related motifs, different from annotated peptide sequences, including one fragment from chicken, two from zebrafish, two ...
Janis, Klovins, Helgi B, Schiöth
openaire +2 more sources
European Journal of Pharmacology, 2021
Microvascular changes and retinal degeneration precede diabetic retinopathy. Oxidative stress alters several intracellular signaling pathways, which form the basis of diabetic retinopathy.
Heba Al‐Hussaini +2 more
semanticscholar +1 more source
Microvascular changes and retinal degeneration precede diabetic retinopathy. Oxidative stress alters several intracellular signaling pathways, which form the basis of diabetic retinopathy.
Heba Al‐Hussaini +2 more
semanticscholar +1 more source
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 2023
We investigated the involvement of agouti-signaling proteins (ASIPs) in morphological pigmentation and physiological color change in flatfishes. We isolated ASIP1 and 2 mRNAs from the skin of starry flounder (Platichthys stellatus), and compared their ...
Duk-Young Kang, Hyo-Chan Kim
semanticscholar +1 more source
We investigated the involvement of agouti-signaling proteins (ASIPs) in morphological pigmentation and physiological color change in flatfishes. We isolated ASIP1 and 2 mRNAs from the skin of starry flounder (Platichthys stellatus), and compared their ...
Duk-Young Kang, Hyo-Chan Kim
semanticscholar +1 more source
Agouti Signal Protein Regulation in Human Melanoma Cells
Pigment Cell Research, 2003Production of the pigment eumelanin is controlled by α‐melanocyte stimulating hormone (α‐MSH) stimulation of melanocortin 1 receptor (Mc1r), whereas production of pheomelanin results from agouti antagonism of α‐MSH signalling through Mc1r. The role of agouti in mouse pigmentation has been extensively investigated but a role for agouti signalling ...
Voisey, Joanne +2 more
openaire +3 more sources
Expression of Agouti Signaling Protein gene (ASIP) in Pigs
Nihon Chikusan Gakkaiho, 2005 OKUMURA, Naohiko +2 more
exaly +3 more sources
General and Comparative Endocrinology, 2012
Hair and feather pigmentation is mainly determined by the distribution of two kinds of melanin, eumelanin and pheomelanin, which produce brown to black and yellow to red colorations, respectively. The agouti signaling protein (ASIP) acts as an antagonist or an inverse agonist of the melanocortin 1 receptor (MC1R), a G protein-coupled receptor for α ...
Chihiro Yoshihara +6 more
semanticscholar +3 more sources
Hair and feather pigmentation is mainly determined by the distribution of two kinds of melanin, eumelanin and pheomelanin, which produce brown to black and yellow to red colorations, respectively. The agouti signaling protein (ASIP) acts as an antagonist or an inverse agonist of the melanocortin 1 receptor (MC1R), a G protein-coupled receptor for α ...
Chihiro Yoshihara +6 more
semanticscholar +3 more sources
Polymorphism of the Goat Agouti Signaling Protein Gene and Its Relationship with Coat Color in Italian and Spanish Breeds [PDF]
Biochemical Genetics, 2011 Agouti signaling protein (ASIP) is one of the key players in the modulation of hair pigmentation in mammals. Binding to the melanocortin 1 receptor, ASIP induces the synthesis of phaeomelanin, associated with reddish brown, red, tan, and yellow coats. We
B. Badaoui +10 more
semanticscholar +2 more sources