Results 191 to 200 of about 17,109 (214)
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Population Differences in the Frequency of the Agouti Signaling Protein g.8818A>G Polymorphism

Pigment Cell Research, 2004
The role of agouti signaling protein (ASIP) in human pigmentation pathways is not definitively understood although its murine homologue regulates, in part, pheomelanogenesis. We have reported an association of a polymorphism in the 3′‐untranslated region of ASIP (g.8818A>G) with dark hair and eye color among a group of European‐Americans (Am J Hum ...
Charnita, Zeigler-Johnson   +5 more
openaire   +2 more sources

Elaborate color patterns of individual chicken feathers may be formed by the agouti signaling protein

General and Comparative Endocrinology, 2012
Hair and feather pigmentation is mainly determined by the distribution of two kinds of melanin, eumelanin and pheomelanin, which produce brown to black and yellow to red colorations, respectively. The agouti signaling protein (ASIP) acts as an antagonist or an inverse agonist of the melanocortin 1 receptor (MC1R), a G protein-coupled receptor for α ...
Chihiro, Yoshihara   +6 more
openaire   +2 more sources

Enterostatin affects cyclic AMP and ERK signaling pathways to regulate Agouti-related Protein (AgRP) expression

Peptides, 2009
Enterostatin, a gut-brain peptide, inhibits dietary fat intake in rats. The purpose of this study was to identify the intracellular signaling pathways that are responsive to enterostatin and that modulate the effects of enterostatin on the expression of Agouti-related protein (AgRP).
Miejung, Park   +2 more
openaire   +2 more sources

Conserved distal promoter of the agouti signaling protein (ASIP) gene controls sexual dichromatism in chickens

General and Comparative Endocrinology, 2012
Brilliant plumage is typical of male birds, thus sexual plumage dichromatism is seen in many avian species; however, the molecular mechanism underlying this remains unclear. The agouti signaling protein (ASIP) is a paracrine factor that stimulates yellow/red pigment (pheomelanin) synthesis and inhibits black/brown pigment (eumelanin) synthesis in ...
Eri, Oribe   +6 more
openaire   +2 more sources

The Interaction of Agouti Signal Protein and Melanocyte Stimulating Hormone to Regulate Melanin Formation in Mammals

Pigment Cell Research, 1996
Important regulatory controls of melanogenesis that operate at the subcellular level to modulate the structural and/or the functional nature of the melanins and melanin granules produced in melanocytes are reviewed. Melanocyte stimulating hormone and agouti signal protein have antagonistic roles and possibly opposing mechanisms of action in the ...
M, Furumura   +4 more
openaire   +2 more sources

109 Agouti-signalling protein impacts blastocyst development in cattle

Reproduction, Fertility and Development, 2022
H. Chaney, J. Current, J. Yao
openaire   +1 more source

Agouti signalling protein (ASIP) gene: molecular cloning, sequence characterisation and tissue distribution in domestic goose

British Poultry Science, 2016
Agouti signalling protein (ASIP) is an endogenous antagonist of melanocortin-1 receptor (MC1R) and is involved in the regulation of pigmentation in mammals. The objective of this study was to identify and characterise the ASIP gene in domestic goose.
J, Zhang   +6 more
openaire   +2 more sources

A polymorphism in the agouti signalling protein (ASIP) is associated with decreased levels of mRNA

Pigment Cell Research, 2006
SummaryTo date, a role for agouti signalling protein (ASIP) in human pigmentation has not been well characterized. It is known that agouti plays a pivotal role in the pigment switch from the dark eumelanin to the light pheomelanin in the mouse. However, because humans do not have an agouti banded hair pattern, its role in human pigmentation has been ...
Voisey, J   +5 more
openaire   +3 more sources

Agouti-signaling protein (ASIP) improves bovine in vitro matured oocyte developmental competence and modulates lipid content

Journal of Assisted Reproduction and Genetics
Bovine embryos produced in vitro are developmentally inferior compared to in vivo derived embryos due to the lack of optimization of the oocyte and embryo culture conditions in vitro. Agouti-signaling protein (ASIP), a secreted protein produced by the bovine oocyte, has been recently shown to aid in acquiring oocyte developmental competence. Therefore,
Heather L. Chaney   +3 more
openaire   +2 more sources

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