Results 81 to 90 of about 17,214 (224)

Impact of long‐term maternal high‐fat, high‐sugar feeding on gastric vagal afferent responses and feeding behaviour in mouse offspring

Experimental Physiology, EarlyView.
Abstract Poor maternal nutrition and excessive gestational weight gain predict future development of obesity in offspring. Preclinically, maternal obesity induced by a high‐fat, high‐sugar diet (HFHSD) induces hyperphagia and obesity in offspring. We hypothesized that this might, in part, reflect reduced peripheral gastric vagal afferent (GVA) satiety ...
Georgia S. Clarke, Hui Li, Elaheh Heshmati, Kelly M. Gembus, Stephanie E. O'Hara, Lisa M. Nicholas, Kathryn L. Gatford, Amanda J. Page   +7 more
wiley   +1 more source

The Genetic Basis of Melanism in Abert’s Squirrel (Sciurus aberti)

Animals
Melanism is widespread in different taxa and has been hypothesized to provide adaptive benefits in certain environments. Melanism is typically caused by mutations in one of two regulatory genes: the Melanocortin 1 Receptor (MC1R) or the Agouti Signaling ...
Lake H. Barrett, Dean Fraga, Richard M. Lehtinen   +2 more
doaj   +1 more source

Canonical and non‐canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology

The Journal of Physiology, EarlyView.
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney, Vincent Marcangeli, Krystel Desjardins, Shima Taherkhani, Gilles Gouspillou   +4 more
wiley   +1 more source

Agouti revisited: transcript quantification of the ASIP gene in bovine tissues related to protein expression and localization. [PDF]

PLoS ONE, 2012
Beside its role in melanogenesis, the agouti signaling protein (ASIP) has been related to obesity. The potentially crucial role in adipocyte development makes it a tempting candidate for economic relevant, fat related traits in farm animals.
Elke Albrecht, Katrin Komolka, Judith Kuzinski, Steffen Maak   +3 more
doaj   +1 more source

Asip(Agouti-signaling protein) aggression gene regulate auditory processing genes in mice [PDF]

, 2020
AbstractCovid-19 strategy of lockdown has affected the lives of millions. The strict actions to enclose the epidemic have exposed many households to inner tensions. Domestic violence has been reported to increase during the lockdown. However, the reasons for this phenomenon have not been thoroughly investigated.
Alexandra Mickael, Pavel Klimovich, Patrick Henckel, Norwin Kubick, Michel E Mickael   +4 more
openaire   +1 more source

Insect‐Derived Bioactives for Glycemic Control and Gut Health: A Review

Food Frontiers, Volume 7, Issue 2, March 2026.
Insect‐derived bioactive compounds (e.g., peptides, polysaccharides) effectively regulate blood glucose through dual mechanisms: directly inhibiting carbohydrate‐digesting enzymes and glucose transporters, and indirectly modulating gut microbiota to enhance intestinal barrier integrity.
Chaoyi Lv, Yuanyuan Huang, Mokhtar Dabbour, Benjamin Kumah Mintah, Ronghai He, Haile Ma   +5 more
wiley   +1 more source

Cell type-specific transcriptomics of hypothalamic energy-sensing neuron responses to weight-loss

eLife, 2015
Molecular and cellular processes in neurons are critical for sensing and responding to energy deficit states, such as during weight-loss. Agouti related protein (AGRP)-expressing neurons are a key hypothalamic population that is activated during energy ...
Fredrick E Henry, Ken Sugino, Adam Tozer, Tiago Branco, Scott M Sternson   +4 more
doaj   +1 more source

Loss of AND-34/BCAR3 Expression in Mice Results in Rupture of the Adult Lens [PDF]

, 2009
PURPOSE. AND-34/BCAR3 (Breast Cancer Anti-Estrogen Resistance 3) associates with the focal adhesion adaptor protein, p130CAS/BCAR1. Expression of AND-34 regulates epithelial cell growth pattern, motility, and growth factor dependence.
Bloom, Alexander B., Freddo, Thomas F., Lerner, Adam, Near, Richard I., Seldin, David C., Smith, Richard S., Toselli, Paul A., Vanden Borre, Pierre   +7 more
core   +2 more sources

The emerging role of CAMK1D in diabetes, metabolism and feeding behaviours: A mechanistic systematic review

Clinical and Translational Discovery, Volume 6, Issue 1, February 2026.
This systematic review synthesizes evidence from published studies, GWAS and grey literature (patents) to show that CAMK1D is implicated in diabetes, obesity, insulin resistance and altered feeding behaviours, with diagnostic potential and mechanistic relevance through regulatory binding and tissue‐specific effects.
Livio Tarchi, Annalisa Di Giacomo, Lorenzo Bonacchi, Andrea Di Santo, Paolo Rovero, Chiara Sassoli, Rachele Garella, Roberta Squecco, Gianluca Villa, Romina Nassini, Francesco De Logu, Tiziana Pisano, Valdo Ricca, Giovanni Castellini   +13 more
wiley   +1 more source

Novel hypophysiotropic AgRP2 neurons and pineal cells revealed by BAC transgenesis in zebrafish [PDF]

, 2017
The neuropeptide agouti-related protein (AgRP) is expressed in the arcuate nucleus of the mammalian hypothalamus and plays a key role in regulating food consumption and energy homeostasis.
Buchshtab, A, Cone, RD, Gothilf, Y, Hawkins, TA, Shainer, I, Wilson, SW   +5 more
core   +1 more source