Results 51 to 60 of about 20,021 (258)

Motivation to Eat—AgRP Neurons and Homeostatic Need [PDF]

Cell Metabolism, 2015
Activation of AgRP neurons potently induces feeding behaviors; however, whether this activity is involved in motivations of feeding behavior is unclear. A recent study in Nature (Betley et al., 2015) reports that AgRP neuron activity conditions learned behavior by transmitting a negative-valence signal: linking AgRP neurons to the preference of ...
Yang, Dengbao, Liu, Tiemin, Williams, Kevin W.   +2 more
openaire   +2 more sources

Hypoxia inducible factor-dependent upregulation of Agrp in glomus type I cells of the carotid body

Molecular Metabolism
Agouti-related peptide (AgRP) is a well-established potent orexigenic peptide primarily expressed in hypothalamic neurons. Nevertheless, the expression and functional significance of extrahypothalamic AgRP remain poorly understood.
Luis Leon-Mercado, Ivan Menendez-Montes, Jonathan Tao, Bandy Chen, David P. Olson, C. Mackaaij, C.G.J. Cleypool, Laurent Gautron   +7 more
doaj   +1 more source

Steady-state energy balance in animal models of obesity and weight loss [PDF]

, 2016
Supported by European Union Seventh Framework Programme (FP7/2007-2013, n°266408 (Full4Health)), the Joint Programme of the Medical Faculty of Norwegian University of Science and Technology (NTNU) and St. Olav’s University Hospital, the Liaison Committee
Barrett, Perry, Cassie, Nikki, Chen, Duan, Johannessen, Helene, Kulseng, Bård, Olsen, Magnus Kringstad, Takeuchi, Koji, Zhao, Chun-Mei   +7 more
core   +2 more sources

TET3 epigenetically controls feeding and stress response behaviors via AGRP neurons

The Journal of Clinical Investigation, 2022
The TET family of dioxygenases promote DNA demethylation by oxidizing 5-methylcytosine to 5-hydroxymethylcytosine (5hmC). Hypothalamic agouti-related peptide–expressing (AGRP-expressing) neurons play an essential role in driving feeding, while also ...
Di Xie, Bernardo Stutz, Feng Li, Fan Chen, Haining Lv, Matija Sestan-Pesa, Jonatas Catarino, Jianlei Gu, Hongyu Zhao, Christopher E. Stoddard, Gordon G. Carmichael, Marya Shanabrough, Hugh S. Taylor, Zhong-Wu Liu, Xiao-Bing Gao, Tamas L. Horvath, Yingqun Huang   +16 more
doaj   +1 more source

MaxElide and clause structure in Scottish Gaelic [PDF]

, 2014
No abstract ...
Thoms, Gary
core   +2 more sources

Temporal Control of Appetite by AgRP Clocks [PDF]

Cell Metabolism, 2019
Neuronal control of diurnal appetitive drive is not well understood. In this issue, a study by Cedernaes et al. (2019) elucidates a key role of AgRP neuronal clocks and delineates the cell-type-specific transcriptional landscape in the temporal regulation of hunger.
openaire   +2 more sources

The role of GluN2A and GluN2B NMDA receptor subunits in AgRP and POMC neurons on body weight and glucose homeostasis

Molecular Metabolism, 2015
Objective: Hypothalamic agouti-related peptide (AgRP) and pro-opiomelanocortin (POMC) expressing neurons play critical roles in control of energy balance.
Aykut Üner, Gabriel H.M. Gonçalves, Wenjing Li, Matheus Porceban, Nicole Caron, Milena Schönke, Eric Delpire, Kenji Sakimura, Christian Bjørbæk   +8 more
doaj   +1 more source

Vagal Blocking for Obesity Control : a Possible Mechanism-Of-Action [PDF]

, 2016
14 September 2016 Erratum to: Vagal Blocking for Obesity Control: a Possible Mechanism-Of-Action Helene Johannessen, David Revesz, Yosuke Kodama, Nikki Cassie, Karolina P Skibicka, Perry Barrett, Suzanne Dickson, Jens Holst, Jens Rehfeld, Geoffrey van ...
Adan, Roger, Barrett, Perry, Ben-Menachem, Elinor, Cassie, Nikki, Chen, Duan, Dickson, Suzanne, Holst, Jens, Johannessen, Helene, Kodama, Yosuke, Kulseng, Bård, Rehfeld, Jens, Revesz, David, Skibicka, Karolina P, van der Plasse, Geoffrey, Zhao, Chun-Mei   +14 more
core   +1 more source

Activity Based Anorexia as an Animal Model for Anorexia Nervosa–A Systematic Review [PDF]

, 2019
Anorexia nervosa (AN) is a severe eating disorder affecting around 1 per 100 persons. However, the knowledge about its underlying pathophysiology is limited.
Schalla, Martha A., Stengel, Andreas
core   +1 more source

Reducing hypothalamic AGRP by RNA interference increases metabolic rate and decreases body weight without influencing food intake

BMC Neuroscience, 2002
Background Several lines of evidence strongly suggest that agouti-related peptide (AGRP) plays a key role in the regulation of metabolic function but ablation of the AGRP gene has no apparent effect on metabolic function.
Mastaitis Jason W, Mizuno Tooru M, Makimura Hideo, Agami Reuven, Mobbs Charles V   +4 more
doaj   +1 more source