Results 61 to 70 of about 20,021 (258)
Effects of Thymoquinone on Hypothalamic NPY and AgRP Gene Expression in Intact and Hypothyroidism- Model Rats [PDF]
Journal of Advanced Biomedical Sciences, 2022 Background & Objective: Thymoquinone is the most important compound of Nigella sativa, which stimulates the activity of thyroid axis in healthy individuals and people with hypothyroidism.
Nasrin Ghahremani, Fariba Mahmoudi
doaj
Pediatric Investigation, EarlyView.Monogenic and syndromic obesity in children often arises from defects in the leptin–melanocortin pathway. Understanding these rare genetic causes not only clarifies mechanisms of appetite regulation but also enables precision therapies, offering hope beyond lifestyle interventions.
Hadel Khalil +2 more
wiley +1 more source
Does an acute bout of high intensity interval exercise suppress appetite in obese women?
Pedagogy of Physical Culture and Sports, 2020 Purpose: The aim of this study was to investigate the 24 hour response of appetite and energy intake and the amount of Agouti-Related Protein to the high intensity interval exercise in obese untrained women.
Sepideh Khalaj, Bahman Mirzaei
doaj +1 more source
Cell Reports, 2023 Summary: Resting metabolic rate (RMR) adaptation occurs during obesity and is hypothesized to contribute to failed weight management. Angiotensin II (Ang-II) type 1 (AT1A) receptors in Agouti-related peptide (AgRP) neurons contribute to the integrative ...
Kirthikaa Balapattabi +16 more
doaj +1 more source
Amylin analogues as a novel perspective in anti‐obesity therapy
British Journal of Pharmacology, EarlyView.Abstract Public health systems face a major challenge because of the worldwide obesity epidemic. The number of obese individuals has increased dramatically and, even in Switzerland which may be considered a relatively “lean” country, the numbers are alarmingly high and have reached almost 50% of the adult population.
Thomas A. Lutz
wiley +1 more source
Cold-induced hyperphagia requires AgRP neuron activation in mice [PDF]
eLife, 2020 To maintain energy homeostasis during cold exposure, the increased energy demands of thermogenesis must be counterbalanced by increased energy intake. To investigate the neurobiological mechanisms underlying this cold-induced hyperphagia, we asked whether agouti-related peptide (AgRP) neurons are activated when animals are placed in a cold environment ...
Jennifer D Deem +14 more
openaire +3 more sources
Literacy in the development of L2 morphosyntax. [PDF]
, 2017 Pre-publication version of: Vainikka, A., M. Young-Scholten, C. Ijuin and S. Jarad. 2017 Literacy in the development of L2 morphosyntax. Proceedings of the 12th LESLLA symposium, Granada.
Vainikka, Anne Marjatta
core +1 more source
Clinical Obesity, Volume 15, Issue 2, April 2025.Summary Chronic stress, characterized by increased long‐term exposure to the glucocorticoid hormone cortisol, is increasingly linked to obesity development. Still, various knowledge gaps persist, including on underlying pathophysiological mechanisms. The aim of the current review is to provide the latest insights on the connection between stress and ...
Robin Lengton +4 more
wiley +1 more source
AGRP neurons modulate fasting-induced anxiolytic effects
Translational Psychiatry, 2019 AbstractRecent studies indicate that activation of hypothalamic Agouti-related protein (Agrp) neurons can increase forage-related/repetitive behavior and decrease anxiety levels. However, the impact of physiological hunger states and food deprivation on anxiety-related behaviors have not been clarified.
Changhong Li +7 more
openaire +2 more sources
p53 and energy balance: meeting hypothalamic AgRP neurons [PDF]
Cell Stress, 2018 Cancer cells feature strong metabolic changes to cope with the high energy demand for cell growth and division. Given the importance of metabolic reprogramming in tumor development, it seems logical that tumor suppressors and oncogenes are also regulating the molecular pathways controlling these processes.
Omar Al-Massadi +2 more
openaire +3 more sources