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Aryl Hydrocarbon Receptor (AHR) Ligands as Selective AHR Modulators (SAhRMs)
International Journal of Molecular Sciences, 2020 The aryl hydrocarbon receptor (AhR) was first identified as the intracellular protein that bound and mediated the toxic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD, dioxin) and dioxin-like compounds (DLCs).
Arul Jayaraman, Un-Ho Jin, Stephen Safe
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The Landscape of AhR Regulators and Coregulators to Fine-Tune AhR Functions
International Journal of Molecular Sciences, 2021 The aryl-hydrocarbon receptor (AhR) is a ligand-activated transcription factor that mediates numerous cellular responses. Originally investigated in toxicology because of its ability to bind environmental contaminants, AhR has attracted enormous ...
Ursula Grohmann +2 more
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AHR in the Intestinal Microenvironment: Safeguarding Barrier Function
Nature Reviews Gastroenterology and Hepatology, 2021Brigitta Stockinger +2 more
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How the AHR Became Important in Cancer: The Role of Chronically Active AHR in Cancer Aggression
International Journal of Molecular Sciences, 2021Jessica E Kenison +2 more
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Role of AHR Ligands in Skin Homeostasis and Cutaneous Inflammation
Cells, 2021Francisco Sánchez Madrid +2 more
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IL4I1 Is a Metabolic Immune Checkpoint That Activates the AHR and Promotes Tumor Progression
Cell, 2020Martina Seiffert +2 more
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AhR and Cancer: From Gene Profiling to Targeted Therapy
International Journal of Molecular Sciences, 2021Nina Tardif +2 more
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