Results 221 to 230 of about 98,913 (262)

Epigenetic and Metabolic Changes That Drive Trained Immunity in Response to Microbes and Vaccines

Immunology, EarlyView.
This graphical abstract illustrates how microbial products, vaccines and microbial metabolites activate pattern‐recognition receptor signalling, inducing metabolic rewiring and epigenetic remodelling. These changes establish long‐lasting trained immunity through the functional reprogramming of haematopoietic progenitors and innate immune cells, thereby
Desalegn Abebaw, Aytenew Atnaf, Bantayehu Addis Tegegne, Abebe Fenta, Bantegzie Selabat, Temesgen Baylie, Yonatan Kindie, Zigale Hibstu Teffera, Mekuriaw Belayneh, Mohammed Jemal, Adane Adugna   +10 more
wiley   +1 more source

Aryl hydrocarbon receptor promotes the proliferation and aggressive progression of colorectal cancer under high-fat diet via activating INPP4B/AKT/SGK3 signaling pathway. [PDF]

Front Oncol
Dong Q, Wu T, Yang Y, Yang Y, Gao B, Shi D, Wang H, Yan Y.   +7 more
europepmc   +1 more source

Effects of an integrated parenting and mental health intervention on violence reduction and caregiver mental health among migrant and displaced families from Myanmar: a pragmatic randomized controlled trial

Journal of Child Psychology and Psychiatry, EarlyView.
Background Caregiver mental ill‐health and violence against children are pervasive in conflict and displacement settings with adverse impacts on child mental health and well‐being. Parenting interventions are effective at reducing violence against children but typically prioritize improving parenting knowledge and skills over preventing or treating ...
Amanda Sim, Stephanie Eagling‐Peche, Khaing Zar Lwin, Seema Vyas, Jamie Lachman, G.J. Melendez‐Torres, Tawanchai Jirapramukpitak, Thidar Soe, Th'Blay Moo, Nway Nway Oo, Mary Soan, Win Thandar Kyaw, Greg Tyrosvoutis, Hannah Van Vijfeijken, Jeslyn Brouwers, Eve S. Puffer   +15 more
wiley   +1 more source

Benzo[a]pyrene-induced AHR activation in human ESCs primes premature neurogenesis in cerebral organoids. [PDF]

J Hazard Mater
Jeong B, Yang L, Ranathunge T, Han YG.
europepmc   +1 more source

Functional Mast Cell Testing Identifies Clinically Relevant Cat Sensitisation

Clinical &Experimental Allergy, EarlyView.
Jiakai Wu, Ran Wang, Gail Gauvreau, Ruth P. Cusack, Silvia Bulfone‐Paus, Clare S. Murray, Angela Simpson   +6 more
wiley   +1 more source

Metabolic health, independent of body mass index, is associated with mortality risk in type 1 diabetes

Journal of Diabetes Investigation, EarlyView.
In type 1 diabetes, mortality was highest in metabolically unhealthy underweight patients, and metabolic unhealthiness was associated with higher cardiovascular disease risk across all BMI categories. Comprehensive metabolic management is needed. ABSTRACT Aims/Introduction Although a low body mass index (BMI) is traditionally associated with high ...
Jung A Kim, Jimi Choi, Kyeong Jin Kim, Soo Myoung Shin, Young‐Eun Kim, Kyoung Jin Kim, Hee Young Kim, Nam Hoon Kim, Sin Gon Kim   +8 more
wiley   +1 more source

Activation of aryl hydrocarbon receptor by cigarette smoke induces oxidative stress, autophagy impairment and cellular senescence. [PDF]

Tob Induc Dis
Shi BY, Hu XD, Liu YC, Hu SM, Zhang GX.
europepmc   +1 more source

Corrigendum to "VSMC-derived 3HAA activates AhR to drive abdominal aortic aneurysm formation via the p62-Nrf2 axis" [Redox Biol. 95, (2026), 104256]. [PDF]

Redox Biol
Ramprasath T, Han YM, Ding Y, Carr SM, Zou MH.   +4 more
europepmc   +1 more source