Results 211 to 220 of about 98,913 (262)

Early sodium‐glucose co‐transporter 2 inhibitor initiation is associated with improved cardiovascular outcomes in type 2 diabetes and acute coronary syndrome

Diabetic Medicine, EarlyView.
Abstract Aims Sodium‐glucose co‐transporter 2 inhibitors have demonstrated cardiovascular benefits in individuals with type 2 diabetes mellitus, but the optimal timing of initiation in those with acute coronary syndrome is not known. This study aims to assess if early therapy at discharge is superior to delayed or no therapy in reduction in major ...
Muhammad Usman Shah, Joanna Kate Ward, Alun Roebuck, Bala Srinivasan, Paul Edward Squires, Claire Elizabeth Hills, Maxime Inghels, Kelvin Lee   +7 more
wiley   +1 more source

Microbiota-Associated Metabolites as Immunometabolic Regulators of Glomerular Inflammation: Disease-Specific Mechanisms and Therapeutic Opportunities. [PDF]

J Inflamm Res
Hou F, Yang L, Liu W, Liu W, Cui Y, Rui H, Liu B.   +6 more
europepmc   +1 more source

Impact of Intensified Chemoimmunotherapy Regimens in Aggressive Non‐Hodgkin Lymphoma on Reproduction Patterns

European Journal of Haematology, EarlyView.
ABSTRACT Concerns about treatment‐related fertility impairment are common among young adult lymphoma survivors. Evidence on the impact of treatment for aggressive non‐Hodgkin lymphoma (NHL) on future childbearing is limited, although many individuals of reproductive age are affected.
Stefanie Antonilli, Anna Marklund, Joshua Entrop, Caroline E. Dietrich, Ingrid Glimelius, Tarec C. El‐Galaly, Alexander Fosså, Harald Holte, Karin E. Smedby, Knut B. Smeland, Sandra Eloranta   +10 more
wiley   +1 more source

Particulate Matter-Induced Skin Injury: A Dual-Pathway AhR-Nrf2 Framework for Epidermal Homeostasis and Therapeutic Targeting. [PDF]

Int J Mol Sci
Lin CH, Yen CH, Wu YT, Chang HS, Ko HH, Chen YF.   +5 more
europepmc   +1 more source

Indoleamine 2,3‐Dioxygenase 1 as an Adjunctive Histopathological Marker of Cholangitis Activity in Primary Biliary Cholangitis

Hepatology Research, EarlyView.
IDO‐1 immunostaining identifies primary biliary cholangitis even in morphologically subtle bile duct lesions. IDO‐1 expression reflects cholangitis activity and is suppressed by ursodeoxycholic acid treatment, indicating its value as a dynamic diagnostic adjunct rather than a static marker of chronic damage.
Kaori Yoshimura, Shinji Shimoda, Ryoka Masuda, Tram Nguyen Thi, Rui Yang, Quynh Nguyen Thi, Dong Le Thanh, Yuko Tamano, Yasunori Sato, Taro Yamashita, Kenichi Harada   +10 more
wiley   +1 more source

A case report series of influenza A virus-induced pulmonary disease with diverse clinical manifestations. [PDF]

Front Med (Lausanne)
Guo L, Zhang Y, Niu X, Zhang D.
europepmc   +1 more source

Trans‐resveratrol alleviates inflammation and improves skin barrier function via aryl hydrocarbon receptor pathway in human reconstructed epidermis

International Journal of Cosmetic Science, EarlyView.
In a cytokine‐challenged human epidermal model, trans‐resveratrol reduces inflammation (IL‐1α) and oxidative stress markers (CYP1A1, CYP1B1), while modulating the expression of barrier‐related genes (LOR, OCLN) and differentiation‐associated CASP14. This supports its role as a multifunctional active for sensitive and compromised skin.
Irini M. Dijkhoff, Sandeep Keshavan, Regina G. Daré, Alke Petri‐Fink, Marc Eeman, Agnès Tessier, Barbara Rothen‐Rutishauser   +6 more
wiley   +1 more source

Pretreatment of keratinocytes with Galactomyces ferment filtrate (GFF) promotes stress resiliency in an in vitro oxidative stress model

International Journal of Cosmetic Science, EarlyView.
GFF pretreatment enhances keratinocyte protection against oxidative stress by mitigating stress‐induced biomolecular changes and gene expression dysregulation. GFF‐pretreated keratinocytes maintain healthy epidermal biology post‐stress, preserving mitochondrial function and proliferative capacity.
Lisa C. Green, Tim Reichling, Holly A. Rovito, Jodie Reed, Xingtao Wei, John M. Snowball, Tom Cambron, Tomohiro Hakozaki   +7 more
wiley   +1 more source

Epidemiology and health burden of infective endocarditis: a comparative analysis of Australian vs global trends from 1990 to 2021

Internal Medicine Journal, EarlyView.
Abstract Background Infective endocarditis (IE) is an uncommon but life‐threatening disease with evolving patient risk profiles and management strategies. However, its impact on the Australian healthcare system has not been described. Aims To quantify the healthcare burden of IE in Australia over time in the past three decades and compare outcomes with
David M. Chye, Kate L. Drummond, Thalys Sampaio Rodrigues, Elizabeth Paratz, Robert Horvath, Eugene Athan, Louise M. Burrell, Natasha E. Holmes, Olivia C. Smibert, Anoop N. Koshy   +9 more
wiley   +1 more source

Compensatory pathways in tryptophan metabolism and immune regulation following IDO inhibition. [PDF]

Mol Biol Rep
Gontijo I, Camurça M, Kfoury JR.
europepmc   +1 more source