Results 191 to 200 of about 98,913 (262)

Sociodemographic, Criminological and Clinical Determinants in Suicide After Release From Prison: A 23‐Year National Cohort Study

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Background Suicide risk is elevated after prison release, but population‐level evidence on temporal risk patterns and associated factors remains limited. We aimed to describe characteristics of individuals who die by suicide after release from Norwegian prisons, compare their suicide mortality with the general population, and examine risk ...
Anne Bukten, Lars Mehlum, Seena Fazel, Nicoline Toresen Lokdam, Torill Tverborgvik, Svetlana Skurtveit, Øystein Bruun Ericson, Louis Favril, Morgan Scarth, Gabriela Rolová, Thomas Clausen, Marianne Riksheim Stavseth   +11 more
wiley   +1 more source

Sinonasal Malignancies in Taiwan (2009-2019): Histologic Distribution, Overall Survival, and Temporal Trends in Hematological Versus Nonhematological Tumors. [PDF]

Laryngoscope Investig Otolaryngol
Wu CH, Lin CH, Liang KL.
europepmc   +1 more source

Stimulant Persistence in Adult ADHD: A Retrospective Analysis of a Large Clinical Cohort

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Introduction Network meta‐analyses suggest dexamphetamines (dAMP) may yield more favourable short‐term outcomes than methylphenidate (MPH) in adults with ADHD, yet evidence on long‐term comparative persistence remains scarce. This study compared 12‐month treatment persistence between MPH and dAMP in a large multicentre cohort and explored ...
R. Wettstein, E. Pirgon, J. Kroesen, V. Navarro‐Ovando, J. C. Kroesen, R. Mathôt, G. Dumont   +6 more
wiley   +1 more source

Lupus Panniculitis Immunoprofiling Reveals a Cytotoxic, Type 1‐Skewed T‐Cell Response With Signs of Metabolic Alteration

Allergy, EarlyView.
Imaging mass cytometry shows lupus panniculitis lesions are dominated by cytotoxic and skin‐homing T cells with abundant macrophages and B‐cell aggregates. Spatial neighborhood analysis reveals organized leukocyte architecture, including B‐cell proximity to naïve T cells and M1 macrophages to cytotoxic T cells.
Milad Ameri, Reihane Ziadlou, Stephan Traidl, Milena Sokolowska, Emmanuel Contassot, Nick Li, Maija Kiuru, Isabel Kolm, Werner Kempf, Emanual Maverakis, Cezmi Akdis, Marie‐Charlotte Brüggen   +11 more
wiley   +1 more source

Deficiency of Mitochondrial Fatty Acid Enzyme, CPT1A, Underlies Airway Epithelial Barrier Dysfunction in Severe Asthma

Allergy, EarlyView.
Mitochondrial fatty acid enzyme, CPT1A, is deficient in the airway epithelium of severe asthma patients. Restoration of CPT1A expression improved epithelial barrier integrity via increasing mitochondrial respiration and ATP production in airway epithelial cells. Restoration of deficient epithelial CPT1A may represent a new treatment approach for severe
Muyun Wang, Haiyang Hu, Kun Wang, Di Wu, Ximing Liao, Jing Gao, Tian Li, Wujian Xu, Shaoyong Gao, Qiang Li, Pankaj Kumar Bhavsar, Wei Gao, Kian Fan Chung   +12 more
wiley   +1 more source

Context-dependent functions of the aryl hydrocarbon receptor in gastrointestinal cancers: from microenvironmental regulation to precision targeted therapy. [PDF]

Front Cell Dev Biol
Ma J, Li S, Qiao Y, Gao Z, Liu J, Song Y, Liu Y, Ji X, Li J, Zhang J, Chang L, Huo B.   +11 more
europepmc   +1 more source

The Origins of Allergy: An Outside‐In, Bioenergetic Hypothesis

Allergy, EarlyView.
ABSTRACT Allergic disease has risen too rapidly for inherited susceptibility to explain it, and the risk variants so far reported lie in the epithelial barrier and in type‐2 immunity. We propose a five‐layer model in which epithelial barrier and bioenergetic dysfunction may precede and promote type‐2 immune deviation rather than arise solely as its ...
Peter K. Smith, Nicholas P. West, Stanley Du Preez, Hugh A. Sampson, Peter W. Hellings, David Price, Liam O'Mahony, Carina Venter, Cezmi A. Akdis, Gil Yosipovitch   +9 more
wiley   +1 more source

The kynurenine pathway in RNA virus infection: immunometabolic control of antiviral defense and viral persistence. [PDF]

Front Immunol
Calderón-Sandate DN, Huerta-Garza MJ, Márquez-Reyna BA, Cañedo-Figueroa DM, Hernández-Rodríguez X, Lira-Hernández FI, Osuna-Ramos JF, Cardoso-Ortiz J, Del Ángel RM, Santos-Mena AO, De Jesús-González LA.   +10 more
europepmc   +1 more source

T Cell Microenvironmental Impacts and Therapeutic Opportunities: Application to Human Testicular Germ Cell Tumors

Andrology, EarlyView.
ABSTRACT Testicular germ cell tumors (TGCT) are the leading malignancy in adolescent and young adult males, yet the immunological and cellular mechanisms governing their tumor microenvironment (TME) remain poorly understood. Here, we present a comprehensive review of TGCT pathobiology with a focus on the immune landscape, particularly the role of tumor‐
R Islam, M Figura, J Heyer, S Lieber, M Huber, KL Loveland, HC Schuppe, Daniela Fietz   +7 more
wiley   +1 more source