Results 171 to 180 of about 271,362 (308)

Anti‐Obesity Pharmacotherapy and Emerging Multimodal Interventions for Obstructive Sleep Apnea

Chronic Diseases and Translational Medicine, EarlyView.
Cellular and molecular mechanisms of obesity‐related obstructive sleep apnea (OSA). ADMA: asymmetric dimethyrarginine, NLRP3: nucleotide‐binding domain, leucine‐rich repeat family, Pyrin domain containing 3, TLR: toll‐like receptors, IL‐1β: interleukin‐1β, IL‐6: interleukin‐6; LPS: lipopolysacharide, ROS: reactive oxygen species, TNF‐α.
Anish Preshy, Cornelius J. Fernandez, Mohammad Hamid Nedai, Joseph M. Pappachan   +3 more
wiley   +1 more source

Is Fel d1 Based Component Resolved Diagnosis Associated With Airway Inflammation in Cat Sensitized Children? [PDF]

Clin Transl Sci
Kaya G, Yüksel H, Taneli F, Yılmaz Ö.
europepmc   +1 more source

Engineering Lipid Nanoparticles for Precision RNA Delivery: Design Principles, Targeting Strategies, and Clinical Prospects

Cancer Nexus, EarlyView.
ABSTRACT Lipid nanoparticles (LNPs) represent the most clinically advanced platform for RNA delivery and have enabled major breakthroughs in vaccines and gene therapies. However, their broader application is still limited by inefficient extrahepatic delivery, immunogenicity, and insufficient control over tissue‐ and cell‐specific targeting. This review
Yu Han, Ying Wang, Xintao Gao, Yan Lei, Yantao Li, Zhiyong Tang   +5 more
wiley   +1 more source

The mTOR Inhibitor Rapamycin Attenuates Ozone-Induced Airway Inflammation and Emphysema In Mice. [PDF]

J Inflamm Res
Tian X, Han L, Huang Y, Zhou Y, Zhang X, Zhang M.   +5 more
europepmc   +1 more source

Cytomorphology and Molecular Profile of Hyalinizing Clear Cell Carcinoma of the Lung: A Case With Mucinous Differentiation

Diagnostic Cytopathology, EarlyView.
ABSTRACT Hyalinizing clear cell carcinoma (HCCC) of the lung is an exceedingly rare salivary gland‐type neoplasm with limited cytomorphologic description. We report a case highlighting these features. A 3 mm incidental left‐airway lesion enlarged to 7 mm over 5 months, prompting radial endobronchial ultrasound (EBUS)‐guided transbronchial biopsy. Touch
Jeffrey Zijie Lin, Lucy Jager
wiley   +1 more source

Mitochondrial pyruvate metabolism in club cells drives airway inflammation. [PDF]

Stem Cell Reports
Wang J, Du C, Hao, Wu Q, Gui B, Li Y, Li K, Li X, Zhang Q, Li L, Chen H.   +10 more
europepmc   +1 more source

RORγt‐APCs: The New Masters of Oral Tolerance

Barrier Immunity, EarlyView.
ABSTRACT Oral tolerance is defined by the hypo‐responsiveness of our body to fed antigens, and its failure can lead to immune‐mediated diseases, such as allergy, chronic inflammation and autoimmune diseases. Decades of research have demonstrated that antigen‐presenting cells (APCs) promote oral tolerance by inducing regulatory T cells (Tregs) and/or ...
Thierry Gauthier, WanJun Chen
wiley   +1 more source

MSC-Exosomes as Novel Therapeutics in Asthma and Allergic Airway Inflammation. [PDF]

Thorac Res Pract
Kurt S, Kimiz-Gebologlu I, Oncel SS.
europepmc   +1 more source

Immunometabolic and Spatiotemporal Control of Tissue‐Resident Memory T Cell Biology

Barrier Immunity, EarlyView.
Tissue‐resident memory T (TRM) cells in barrier tissues provide a frontline defense against invading pathogens. Immune (Signals 1–3) and nutrient (Signal 4) cues play an integral role in directing TRM formation and heterogeneity. The spatial and temporal organization of these signals establishes durable TRM cells across tissues, enabling diverse ...
Jana L. Raynor, Hongbo Chi
wiley   +1 more source

Falcarindiol alleviates airway inflammation and oxidative stress in asthma through Nrf2 pathway activation. [PDF]

Sci Rep
Jiang X, Lai S, Lin Z, Lai F, Wu H.
europepmc   +1 more source